18f-faza and carbon-11-methionine

In the present case, we report the first experience of a patient with high-grade glioma who underwent dual F-FAZA PET/CT imaging for intratumoral hypoxia assessment, before treatment, and for therapy monitoring in the suspicious of recurrence, as part of a clinical research protocol. In addition, despite the diagnosis of glioblastoma, the patient at 3 years from diagnosis was alive and underwent C-methionine simultaneous PET/MRI for disease monitoring after treatment, showing stability of disease. The multitracer capability of PET in assessing different and complementary metabolic features along with the use of a last-generation scanner as PET/MRI in brain oncology are here enlighten.

Topics: Adult; Amino Acids; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Neoplasm Grading; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Tumor Hypoxia