Page last updated: 2024-09-03

18-oxocortisol and 18-hydroxycortisol

18-oxocortisol has been researched along with 18-hydroxycortisol in 30 studies

Compound Research Comparison

Studies (18-oxocortisol)	Trials (18-oxocortisol)	Recent Studies (post-2010) (18-oxocortisol)	Studies (18-hydroxycortisol)	Trials (18-hydroxycortisol)	Recent Studies (post-2010) (18-hydroxycortisol)
56	2	14	61	2	11

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (20.00)	18.7374
1990's	9 (30.00)	18.2507
2000's	6 (20.00)	29.6817
2010's	6 (20.00)	24.3611
2020's	3 (10.00)	2.80

Authors

Authors	Studies
Ulick, S	1
Foecking, MF; Ganguly, A; Gomez-Sanchez, CE; Holland, OB; Zager, PG	1
Ferris, MW; Foecking, MF; Gomez-Sanchez, CE; Gomez-Sanchez, EP	1
Clore, JN; Estep, HL; Gomez-Sanchez, CE; Watlington, CO	1
Ganguly, A; Gill, JR; Gomez-Sanchez, CE; Gordon, RD	1
Gomez-Sanchez, CE; Gordon, RD; Hamlet, SM; Klemm, SA; Tunny, TJ	1
Gomez-Sanchez, CE; Gomez-Sanchez, EP; Holland, OB	1
Gomez-Sanchez, CE; Miyazaki, S; Morita, H; Mune, T; Yamakita, N; Yasuda, K; Yoshida, H	1
Chavarri, MR; Cozza, EN; Foecking, MF; Gomez-Sanchez, CE	1
Chiba, H	4
Miyachi, Y; Shimojo, M; Ueshiba, H	1
Gómez-Sánchez, CE	1
Aupetit-Faisant, B; Corvol, P; Curnow, KM; Foekling, M; Gomez-Sanchez, C; Jeunemaitre, X; Mulatero, P; Pascoe, L; Veglio, F	1
Gomez-Sanchez, CE; Miyazaki, S; Mune, T; Nakai, T; Yamakita, N; Yasuda, K; Yoshida, H	1
Chiandussi, L; di Cella, SM; Gomez-Sanchez, CE; Mengozzi, G; Milan, A; Mulatero, P; Veglio, F; Williams, TA	1
Aycock, K; Christensen, V; Gomez-Sanchez, CE; Gomez-Sanchez, EP; Morra di Cella, S; Mulatero, P; Veglio, F; Zhu, Z	1
Connell, JM; Davies, E; Fraser, R; Freel, EM; Friel, EC; Shakerdi, LA; Wallace, AM	1
Bernhardt, M; Bernhardt, R; Connell, JM; Davies, E; Fraser, R; Freel, EM; Ingram, M; Ingram, R; Wallace, AM	1
Mulatero, P	1
di Cella, SM; Gomez-Sanchez, CE; Gomez-Sanchez, EP; Manzo, M; Mengozzi, G; Monticone, S; Mulatero, P; Rabbia, F; Schiavone, D; Terzolo, M; Veglio, F	1
Arai, Y; Gomez-Sanchez, CE; Honma, S; Ito, S; Iwakura, Y; Kudo, M; Morimoto, R; Nakamura, Y; Okuyama, M; Omata, K; Ono, Y; Rainey, WE; Sasamoto, H; Sasano, H; Satoh, F; Seiji, K; Takase, K; Yamashita, K	1
Gomez-Sanchez, CE; Lenders, JWM; Reincke, M; Williams, TA	1
Fukusaki, E; Higashi, T; Nishikawa, T; Nishimoto, K; Ohtsuki, S; Shimma, S; Suematsu, M; Sugiura, Y; Sugiyama, E; Takeo, E; Uemura, T; Yasuda, M	1
Beuschlein, F; Feuchtinger, A; Gomez-Sanchez, C; Kirchner, T; Knösel, T; Kunzke, T; Ludwig, P; Murakami, M; Reincke, M; Rhayem, Y; Strom, TM; Sun, N; Walch, AK; Williams, TA	1
Ishii, K; Morimoto, R; Sasano, H; Satoh, F; Tezuka, Y; Turcu, AF; Udager, AM; Yamazaki, Y; Zhao, L	1
Chang, CC; Chang, YL; Chen, GY; Chen, PT; Lee, BC; Lin, YH; Liu, KL; Weng, TI; Wu, VC	1
Ozeki, Y; Shibata, H	1

Reviews

6 review(s) available for 18-oxocortisol and 18-hydroxycortisol

Article	Year
Two uncommon causes of mineralocorticoid excess. Syndrome of apparent mineralocorticoid excess and glucocorticoid-remediable aldosteronism. Endocrinology and metabolism clinics of North America, 1991, Volume: 20, Issue:2 Topics: Glucocorticoids; Humans; Hydrocortisone; Hyperaldosteronism; Mineralocorticoids; Syndrome	1991
[18-Hydroxycortisol (18-OH-F) and 18-oxocortisol (18-oxoF)]. Nihon rinsho. Japanese journal of clinical medicine, 1995, Volume: 53 Su Pt 2 Topics: Humans; Hydrocortisone; Methods	1995
Primary aldosteronism and its variants. Cardiovascular research, 1998, Volume: 37, Issue:1 Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex Function Tests; Adrenal Gland Neoplasms; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hyperplasia; Incidence; Zona Glomerulosa	1998
[18-hydroxycortisol, 18-oxocortisol, and 6 beta-hydroxycortisol]. Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57 Suppl Topics: Humans; Hydrocortisone; Hyperaldosteronism	1999
[18-Hydroxycortisol, 18-oxocortisol, and 6beta-hydroxycortisol]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8 Topics: ACTH Syndrome, Ectopic; Adrenal Cortex Diseases; Adrenocortical Hyperfunction; Biomarkers; Chromatography, High Pressure Liquid; Cushing Syndrome; Diagnosis, Differential; Humans; Hydrocortisone; Hyperaldosteronism; Immunoenzyme Techniques; Pituitary ACTH Hypersecretion; Radioimmunoassay; Reference Values; Specimen Handling	2005
DIAGNOSIS OF ENDOCRINE DISEASE: 18-Oxocortisol and 18-hydroxycortisol: is there clinical utility of these steroids? European journal of endocrinology, 2018, Volume: 178, Issue:1 Topics: Biomarkers; Diagnosis, Differential; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Male	2018

Trials

1 trial(s) available for 18-oxocortisol and 18-hydroxycortisol

Article	Year
ACTH Stimulation Maximizes the Accuracy of Peripheral Steroid Profiling in Primary Aldosteronism Subtyping. The Journal of clinical endocrinology and metabolism, 2021, 09-27, Volume: 106, Issue:10 Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Cosyntropin; Diagnostic Techniques, Endocrine; Female; Humans; Hydrocortisone; Hyperaldosteronism; Male; Middle Aged; Predictive Value of Tests; Steroids; Stimulation, Chemical	2021

Article

Year

ACTH Stimulation Maximizes the Accuracy of Peripheral Steroid Profiling in Primary Aldosteronism Subtyping.

The Journal of clinical endocrinology and metabolism, 2021, 09-27, Volume: 106, Issue:10

Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Cosyntropin; Diagnostic Techniques, Endocrine; Female; Humans; Hydrocortisone; Hyperaldosteronism; Male; Middle Aged; Predictive Value of Tests; Steroids; Stimulation, Chemical

2021

Other Studies

23 other study(ies) available for 18-oxocortisol and 18-hydroxycortisol

Article	Year
18-oxocortisol: effect of dexamethasone, ACTH and sodium restriction. Journal of steroid biochemistry, 1989, Volume: 32, Issue:3 Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Desoxycorticosterone; Dexamethasone; Diet, Sodium-Restricted; Female; Humans; Hydrocortisone; Male; Middle Aged	1989
Synthesis of 18-hydroxycortisol and 18-oxocortisol in bovine adrenal slices. Journal of steroid biochemistry, 1989, Volume: 33, Issue:4A Topics: Adrenal Glands; Aldosterone; Animals; Cattle; Hydrocortisone; In Vitro Techniques; Radioimmunoassay	1989
Effect of chronic adrenocorticotropin stimulation on the excretion of 18-hydroxycortisol and 18-oxocortisol. The Journal of clinical endocrinology and metabolism, 1988, Volume: 67, Issue:2 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Humans; Hydrocortisone; Male; Stimulation, Chemical; Tetrahydrocortisol; Tetrahydrocortisone	1988
Glucocorticoid-suppressible aldosteronism: a disorder of the adrenal transitional zone. The Journal of clinical endocrinology and metabolism, 1988, Volume: 67, Issue:3 Topics: Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Animals; Child; Dexamethasone; Female; Humans; Hydrocortisone; Hyperaldosteronism; In Vitro Techniques; Male; Middle Aged; Rana catesbeiana	1988
Adrenal transitional zone steroids, 18-oxo and 18-hydroxycortisol, useful in the diagnosis of primary aldosteronism, are ACTH-dependent. Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:4 Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Chromatography, High Pressure Liquid; Dexamethasone; Humans; Hydrocortisone; Hyperaldosteronism; Radioimmunoassay; Spectrophotometry, Ultraviolet	1988
Role of 18-hydroxylated cortisols in hypertension. Journal of steroid biochemistry, 1987, Volume: 27, Issue:4-6 Topics: Humans; Hydrocortisone; Hypertension; Renin	1987
Simultaneous measurement of plasma 18-oxocortisol and 18-hydroxycortisol levels in normal man. European journal of endocrinology, 1994, Volume: 131, Issue:1 Topics: Adrenocorticotropic Hormone; Adult; Dexamethasone; Female; Humans; Hydrocortisone; Male; Posture; Reference Values	1994
Synthesis of 18-hydroxycortisol and 18-oxocortisol in bovine adrenal zona glomerulosa mitochondria. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 203, Issue:3 Topics: 18-Hydroxycorticosterone; Aldosterone; Animals; Binding, Competitive; Cattle; Corticosterone; Dithionite; Hydrocortisone; Kinetics; Mitochondria; NADP; Spectrophotometry; Zona Glomerulosa	1993
18-Hydroxycortisol and 18-oxocortisol in Cushing's syndrome. Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Hyperplasia; Male; Middle Aged	1997
Recombinant CYP11B genes encode enzymes that can catalyze conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol, and 18-oxocortisol. The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:11 Topics: Case-Control Studies; Catalysis; Cortodoxone; Cytochrome P-450 CYP11B2; Gene Conversion; Genetic Code; Genetic Testing; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Renin; Steroid 11-beta-Hydroxylase	1998
Regulation of 18-oxocortisol and 18-hydroxycortisol by the renin-angiotensin system and ACTH in man. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:3 Topics: 18-Hydroxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Dexamethasone; Diet; Humans; Hydrocortisone; Japan; Male; Posture; Renin; Renin-Angiotensin System; Sodium	1993
Glucocorticoid remediable aldosteronism: low morbidity and mortality in a four-generation italian pedigree. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:7 Topics: Adult; Aldosterone; Blood Pressure; Crossing Over, Genetic; Cytochrome P-450 CYP11B2; Female; Glucocorticoids; Humans; Hydrocortisone; Hyperaldosteronism; Italy; Male; Middle Aged; Pedigree; Phenotype; Pregnancy; Pregnancy Complications; Steroid 11-beta-Hydroxylase	2002
A time-resolved fluoroimmunoassay for 18-oxocortisol and 18-hydroxycortisol. Development of a monoclonal antibody to 18-oxocortisol. The Journal of steroid biochemistry and molecular biology, 2002, Volume: 82, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Biomarkers; Female; Fluoroimmunoassay; Humans; Hydrocortisone; Hyperaldosteronism; Male; Mice	2002
Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:9 Topics: Adult; Animals; CHO Cells; Cortisone; Cricetinae; Cytochrome P-450 CYP11B2; Dexamethasone; Humans; Hydrocortisone; Male; Steroid 11-beta-Hydroxylase; Transfection; Zona Fasciculata; Zona Glomerulosa	2004
Endogenous corticosteroid biosynthesis in subjects after bilateral adrenalectomy. Clinical endocrinology, 2007, Volume: 66, Issue:5 Topics: Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrenalectomy; Adult; Aged; Aldosterone; Dexamethasone; Female; Gas Chromatography-Mass Spectrometry; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Postoperative Period; Radioimmunoassay; Renin; Tetrahydrocortisol; Tetrahydrocortisone	2007
A new form of hereditary primary aldosteronism: familial hyperaldosteronism type III. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8 Topics: Humans; Hydrocortisone; Hyperaldosteronism; Steroid 11-beta-Hydroxylase	2008
[18-Hydroxycortisol, 18-oxocortisol, and 6beta-hydroxycortisol]. Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 7 Topics: Adult; Child; Humans; Hydrocortisone; Hyperaldosteronism	2010
18-hydroxycorticosterone, 18-hydroxycortisol, and 18-oxocortisol in the diagnosis of primary aldosteronism and its subtypes. The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:3 Topics: 18-Hydroxycorticosterone; Adult; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension	2012
Measurement of peripheral plasma 18-oxocortisol can discriminate unilateral adenoma from bilateral diseases in patients with primary aldosteronism. Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:5 Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Biomarkers; Diagnosis, Differential; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Hyperaldosteronism; Male; Middle Aged; Reproducibility of Results; Retrospective Studies; Tomography, X-Ray Computed	2015
Tandem Mass Spectrometry Imaging Reveals Distinct Accumulation Patterns of Steroid Structural Isomers in Human Adrenal Glands. Analytical chemistry, 2019, 07-16, Volume: 91, Issue:14 Topics: Adrenal Glands; Aldosterone; Glucocorticoids; Humans; Hydrocortisone; Isomerism; Mineralocorticoids; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Steroids; Tandem Mass Spectrometry	2019
In situ metabolomics of aldosterone-producing adenomas. JCI insight, 2019, 09-05, Volume: 4, Issue:17 Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Calcium Channels, L-Type; Cohort Studies; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genotype; Humans; Hydrocortisone; Hyperaldosteronism; Male; Metabolomics; Middle Aged; Mutation; Phenotype; Steroid 11-beta-Hydroxylase	2019
Optimizing adrenal vein sampling in primary aldosteronism subtyping through LC-MS/MS and secretion ratios of aldosterone, 18-oxocortisol, and 18-hydroxycortisol. Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:8 Topics: Adrenocorticotropic Hormone; Aldosterone; Chromatography, Liquid; Humans; Hydrocortisone; Hyperaldosteronism; Retrospective Studies; Steroids; Tandem Mass Spectrometry	2023
Utility of 18-hydroxycortisol and 18-oxocortisol: potential markers of aldosterone-producing adenomas. Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:10 Topics: Adenoma; Aldosterone; Chromatography, Liquid; Humans; Hydrocortisone; Hyperaldosteronism; Tandem Mass Spectrometry	2023