18-ethynyldeoxycorticosterone has been researched along with desoxycorticosterone in 5 studies
| Studies (18-ethynyldeoxycorticosterone) | Trials (18-ethynyldeoxycorticosterone) | Recent Studies (post-2010) (18-ethynyldeoxycorticosterone) | Studies (desoxycorticosterone) | Trials (desoxycorticosterone) | Recent Studies (post-2010) (desoxycorticosterone) |
|---|---|---|---|---|---|
| 5 | 1 | 0 | 7,588 | 52 | 284 |
| Protein | Taxonomy | 18-ethynyldeoxycorticosterone (IC50) | desoxycorticosterone (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 3 | Rattus norvegicus (Norway rat) | 8.4 | |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | 1.9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiou, S; Gomez-Sanchez, CE; Yamakita, N | 2 |
| Holbert, GW; Johnston, JO; Wright, CL | 1 |
| Foecking, MF; Gomez-Sanchez, CE; Gomez-Sanchez, EP; Zhou, MY | 1 |
| Cozza, EN; Gomez-Sanchez, CE; Matković, L | 1 |
1 trial(s) available for 18-ethynyldeoxycorticosterone and desoxycorticosterone
| Article | Year |
|---|---|
Enzyme-activated inhibitors of steroidal hydroxylases.
Topics: Adrenal Cortex Hormones; Androstenedione; Animals; Aromatase Inhibitors; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Drug Tolerance; Estrogens; Humans; Male; Mineralocorticoids; Pargyline; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases; Zona Glomerulosa | 1995 |
4 other study(ies) available for 18-ethynyldeoxycorticosterone and desoxycorticosterone
| Article | Year |
|---|---|
Inhibition of aldosterone biosynthesis by 18-ethynyl-deoxycorticosterone.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Cells, Cultured; Desoxycorticosterone; Dose-Response Relationship, Drug; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Time Factors; Zona Glomerulosa | 1991 |
18-Ethynyl-deoxycorticosterone inhibition of steroid production is different in freshly isolated compared to cultured calf zona glomerulosa cells.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Analysis of Variance; Angiotensin II; Animals; Cattle; Cells, Cultured; Desoxycorticosterone; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Potassium; Zona Fasciculata; Zona Glomerulosa | 1993 |
Inhibition of steroidogenesis in rat adrenal cells by 18-ethynyldeoxycorticosterone: evidence for an alternative pathway of aldosterone biosynthesis.
Topics: Adrenal Glands; Aldosterone; Animals; Cells, Cultured; Desoxycorticosterone; Rats; Rats, Sprague-Dawley | 1997 |
Inhibition of aldosterone production in rat adrenal mitochondria by 18-ethynyl-11-deoxycorticosterone: a simple model for kinetic interpretation of mechanism-based inhibitors.
Topics: Adrenal Cortex; Aldosterone; Animals; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Desoxycorticosterone; Enzyme Inhibitors; Kinetics; Mitochondria; Models, Biological; NADP; Rats; Zona Glomerulosa | 2001 |