Page last updated: 2024-09-04

18-ethynyldeoxycorticosterone and aldosterone

18-ethynyldeoxycorticosterone has been researched along with aldosterone in 3 studies

Compound Research Comparison

Studies
(18-ethynyldeoxycorticosterone)
Trials
(18-ethynyldeoxycorticosterone)
Recent Studies (post-2010)
(18-ethynyldeoxycorticosterone)
Studies
(aldosterone)
Trials
(aldosterone)
Recent Studies (post-2010) (aldosterone)
51025,3331,5174,169

Protein Interaction Comparison

ProteinTaxonomy18-ethynyldeoxycorticosterone (IC50)aldosterone (IC50)
Mineralocorticoid receptor Homo sapiens (human)0.0048
Mineralocorticoid receptorRattus norvegicus (Norway rat)0.043

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiou, S; Gomez-Sanchez, CE; Yamakita, N1
Foecking, MF; Gomez-Sanchez, CE; Gomez-Sanchez, EP; Zhou, MY1
Cozza, EN; Gomez-Sanchez, CE; Matković, L1

Other Studies

3 other study(ies) available for 18-ethynyldeoxycorticosterone and aldosterone

ArticleYear
Inhibition of aldosterone biosynthesis by 18-ethynyl-deoxycorticosterone.
    Endocrinology, 1991, Volume: 129, Issue:5

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Cells, Cultured; Desoxycorticosterone; Dose-Response Relationship, Drug; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Time Factors; Zona Glomerulosa

1991
Inhibition of steroidogenesis in rat adrenal cells by 18-ethynyldeoxycorticosterone: evidence for an alternative pathway of aldosterone biosynthesis.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 62, Issue:2-3

    Topics: Adrenal Glands; Aldosterone; Animals; Cells, Cultured; Desoxycorticosterone; Rats; Rats, Sprague-Dawley

1997
Inhibition of aldosterone production in rat adrenal mitochondria by 18-ethynyl-11-deoxycorticosterone: a simple model for kinetic interpretation of mechanism-based inhibitors.
    Journal of biochemistry, 2001, Volume: 129, Issue:3

    Topics: Adrenal Cortex; Aldosterone; Animals; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Desoxycorticosterone; Enzyme Inhibitors; Kinetics; Mitochondria; Models, Biological; NADP; Rats; Zona Glomerulosa

2001