17-octadecynoic acid and 20-hydroxy-5,8,11,14-eicosatetraenoic acid

17-octadecynoic acid has been researched along with 20-hydroxy-5,8,11,14-eicosatetraenoic acid in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (32.14)18.2507
2000's19 (67.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Imig, JD; Kaldunski, M; Ortiz de Montellano, PR; Roman, RJ; Sui, Z; Zou, AP1
Imig, JD; Ortiz de Montellano, PR; Roman, RJ; Sui, Z; Zou, AP1
Falck, JR; Fleming, JT; Gebremedhin, D; Harder, DR; Jacobs, ER; Roman, RJ; Zou, AP1
Birks, EK; Harder, DR; Imig, JD; Lange, AR; Liard, JF; Lombard, JH; Narayanan, J; Roman, RJ1
Balazy, M; Falck, JR; Lu, M; Reddy, KM; Wang, W; Zhu, Y1
Falcone, JC; Grider, JS; Jackson, BA; Kilpatrick, EL; Ott, CE1
Ito, O; Roman, RJ1
Faraci, FM; Sobey, CG1
Benzoni, D; Bernard, N; Messer-Létienne, I; Roman, RJ; Sassard, J1
Bloswick, BP; Chen, WB; Lasker, JM; Powell, PK; Wilson, PD; Wolf, I1
Falck, JR; Frisbee, JC; Lombard, JH1
Escalante, B; López-Sánchez, P; Martínez-Ayala, S; Rios, A; Sánchez-Mendoza, A; Vázquez-Cruz, B1
Alonso-Galicia, M; Falck, JR; Kunert, MP; Lombard, JH; Roman, RJ1
Falck, JR; Frisbee, JC; Krishna, UM; Lombard, JH; Roman, RJ1
Falck, JR; Frisbee, JC; Lombard, JH; Murali Krishna, U; Roman, RJ1
Abe, M; Arima, S; Chiba, Y; Endo, Y; Ito, O; Ito, S; Kohagura, K; Omata, K1
Cambj-Sapunar, L; Harder, DR; Hudetz, AG; Kametani, S; Kehl, F; Maier, KG; Miyata, N; Okamoto, H; Roman, RJ; Schulte, ML; Zagorac, D1
Falck, JR; Gisolfi, CV; Krishna, UM; Looft-Wilson, RC1
Grider, JS; Jackson, BA; Ott, CE1
Dietz, JR; Landon, CS; Lee, SJ; Nazian, SJ1
Campbell, WB; Endsley, MP; Falck, JR; Gross, ER; Gross, GJ; Isbell, MA; Moore, JM; Nithipatikom, K1
Caron, N; Declèves, AE; El Hajjam, A; Falck, JR; Joly, E; Kramp, R1
Acquier, A; Kirchheimer, C; Mendez, CF; Nowicki, S1
Bridges, AS; Hall, JE; Kornbluth, S; Paine, MF; Tidwell, RR; Wang, MZ; Wu, JQ; Zeldin, DC1
Gebremedhin, D; Harder, DR; Yamaura, K1
Guo, L; Leu, C; Li, Y; Tang, X; Wang, Z; Zheng, X; Zhu, D1
Ao, Y; Cheng, H; Li, Y; Lv, X; Peng, R; Wan, J; Yang, J1
Gu, F; Gu, RM; Kong, S; Liu, L; Wang, L; Wang, M; Wang, WH; Wu, P; Yang, L; Zhai, Y; Zhang, C; Zhang, J; Zhang, Y1

Other Studies

28 other study(ies) available for 17-octadecynoic acid and 20-hydroxy-5,8,11,14-eicosatetraenoic acid

ArticleYear
Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: Animals; Arachidonic Acid; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Homeostasis; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Medulla; Kinetics; Male; Miconazole; Microcirculation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation

1994
Cytochrome P-450 inhibitors alter afferent arteriolar responses to elevations in pressure.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arterioles; Cytochrome P-450 Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney; Kidney Cortex; Miconazole; Microsomes; Muscle, Smooth, Vascular; Oxazines; Perfusion; Rats; Rats, Sprague-Dawley; Renal Circulation

1994
20-HETE is an endogenous inhibitor of the large-conductance Ca(2+)-activated K+ channel in renal arterioles.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Animals; Arachidonic Acid; Arterioles; Calcium; Cytochrome P-450 Enzyme System; Electric Conductivity; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Renal Circulation; Vasoconstriction

1996
Identification of a putative microvascular oxygen sensor.
    Circulation research, 1996, Volume: 79, Issue:1

    Topics: Animals; Base Sequence; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Microcirculation; Mixed Function Oxygenases; Molecular Probes; Molecular Sequence Data; Muscle, Skeletal; Oxygen; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction

1996
Effect of angiotensin II on the apical K+ channel in the thick ascending limb of the rat kidney.
    The Journal of general physiology, 1996, Volume: 108, Issue:6

    Topics: Angiotensin II; Animals; Cell Membrane; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Loop of Henle; Naphthalenes; NG-Nitroarginine Methyl Ester; Patch-Clamp Techniques; Penicillamine; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sodium

1996
P450 arachidonate metabolites mediate bradykinin-dependent inhibition of NaCl transport in the rat thick ascending limb.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Bradykinin; Calcium; Cyclic GMP; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney Tubules, Distal; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride

1997
Role of 20-HETE in elevating chloride transport in the thick ascending limb of Dahl SS/Jr rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Animals; Biological Transport; Chlorides; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Epithelial Cells; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Kidney Medulla; Loop of Henle; Male; Membrane Potentials; Mixed Function Oxygenases; Rats; Rats, Inbred Dahl; Rats, Inbred Lew; Rats, Sprague-Dawley

1999
Role of soluble guanylate cyclase in dilator responses of the cerebral microcirculation.
    Brain research, 1999, Mar-13, Volume: 821, Issue:2

    Topics: Acetylcholine; Adenosine; Animals; Brain; Cerebral Arteries; Cerebrovascular Circulation; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Growth Inhibitors; Guanylate Cyclase; Hydroxyeicosatetraenoic Acids; Indazoles; Microcirculation; Nitric Oxide; Nitroprusside; Oxadiazoles; Platelet Aggregation Inhibitors; Quinoxalines; Rabbits; Solubility; Vasodilation; Vasodilator Agents

1999
20-Hydroxyeicosatetraenoic acid and renal function in Lyon hypertensive rats.
    European journal of pharmacology, 1999, Aug-13, Volume: 378, Issue:3

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Body Weight; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Heptanoic Acids; Hydroxyeicosatetraenoic Acids; Hypertension; In Vitro Techniques; Kidney; Male; Miconazole; Organ Size; Oxygenases; Rats; Receptors, Thromboxane; Renal Circulation; Systole; Vascular Resistance; Vasodilation

1999
Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11.
    The Journal of biological chemistry, 2000, Feb-11, Volume: 275, Issue:6

    Topics: Antibodies; Arachidonic Acid; Blood Pressure; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Hydroxylation; Immunohistochemistry; Kidney; Kidney Tubules; Kinetics; Liver; Microsomes; Vasoconstrictor Agents

2000
Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5

    Topics: Acetylcholine; Amides; Angiotensin II; Animals; Arterioles; Blood Pressure; Cardiovascular Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Hypertension, Renal; Male; Microscopy, Video; Mixed Function Oxygenases; Muscle, Skeletal; Nitroprusside; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sulfones

2000
Angiotensin II modulates ion transport in rat proximal tubules through CYP metabolites.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: Adrenalectomy; Angiotensin II; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Indomethacin; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Ouabain; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes

2000
Cytochrome P-450 omega-hydroxylase: a potential O(2) sensor in rat arterioles and skeletal muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:4

    Topics: Amides; Animals; Arterioles; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Kidney; Liver; Male; Mixed Function Oxygenases; Muscle, Skeletal; Oxygen; Rats; Rats, Sprague-Dawley; Sulfones; Vasoconstriction

2001
20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats.
    Microcirculation (New York, N.Y. : 1994), 2001, Volume: 8, Issue:1

    Topics: Amides; Animals; Arteries; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Mixed Function Oxygenases; Muscle, Skeletal; Potassium Channel Blockers; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Sulfones; Vascular Resistance

2001
Altered mechanisms underlying hypoxic dilation of skeletal muscle resistance arteries of hypertensive versus normotensive Dahl rats.
    Microcirculation (New York, N.Y. : 1994), 2001, Volume: 8, Issue:2

    Topics: Animals; Arachidonic Acid; Arteries; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Hypertension; Hypoxia; In Vitro Techniques; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Dahl; Vascular Resistance; Vasodilation

2001
Involvement of cytochrome P450 metabolites in the vascular action of angiotensin II on the afferent arterioles.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Arterioles; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Miconazole; Norepinephrine; Rabbits; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2001
20-HETE contributes to the acute fall in cerebral blood flow after subarachnoid hemorrhage in the rat.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:4

    Topics: Amidines; Animals; Carbon Dioxide; Cerebrovascular Circulation; Enzyme Inhibitors; Erythrocytes; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Microscopy, Video; Partial Pressure; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Subarachnoid Hemorrhage; Time Factors

2002
20-HETE pathway antagonists inhibit rat small mesenteric artery tone.
    Microvascular research, 2002, Volume: 64, Issue:2

    Topics: Amides; Animals; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Mesenteric Arteries; Pressure; Rats; Rats, Sprague-Dawley; Sulfones

2002
Dopamine D1 receptor-dependent inhibition of NaCl transport in the rat thick ascending limb: mechanism of action.
    European journal of pharmacology, 2003, Jul-25, Volume: 473, Issue:2-3

    Topics: Animals; Benzazepines; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney Medulla; Male; Naphthalenes; Phospholipases A; Phospholipases A2; Pyrones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Signal Transduction; Sodium Chloride; Staurosporine

2003
Cytochrome P-450 metabolites in endothelin-stimulated cardiac hormone secretion.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:5

    Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Cytochrome P-450 Enzyme System; Endothelin-1; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Myocardium; Myocytes, Cardiac; Peptide Fragments; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley

2004
Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway.
    Circulation research, 2004, Oct-15, Volume: 95, Issue:8

    Topics: 8,11,14-Eicosatrienoic Acid; Amides; Animals; Arachidonic Acids; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Fatty Acids, Unsaturated; Female; Hydroxyeicosatetraenoic Acids; Isoenzymes; Male; Miconazole; Microsomes; Mixed Function Oxygenases; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Sulfones

2004
Changes in renal haemodynamics induced by indomethacin in the rat involve cytochrome P450 arachidonic acid-dependent epoxygenases.
    Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:10

    Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hemodynamics; Hydroxyeicosatetraenoic Acids; Indomethacin; Kidney; Male; Miconazole; Rats; Rats, Wistar; Renal Circulation; Vasodilation

2004
Role of 20-HETE in D1/D2 dopamine receptor synergism resulting in the inhibition of Na+-K+-ATPase activity in the proximal tubule.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:5

    Topics: Animals; Colforsin; Diglycerides; Dopamine; Dopamine Agonists; Drug Synergism; Fatty Acids, Unsaturated; Fenoldopam; Hydroxyeicosatetraenoic Acids; Kidney Tubules, Proximal; Male; Protein Kinase C-alpha; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions; Tissue Distribution

2007
Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11

    Topics: Amidines; Antibodies; Antiparasitic Agents; Arachidonic Acid; Benzamidines; Benzoflavones; Butyrophenones; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Intestinal Mucosa; Intestines; Kinetics; Methylation; Microsomes; Oxygenases; Piperidines; Prodrugs; Recombinant Proteins; Stereoisomerism

2007
Role of 20-HETE in the hypoxia-induced activation of Ca2+-activated K+ channel currents in rat cerebral arterial muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1

    Topics: Animals; Antioxidants; Calcium; Cell Hypoxia; Cerebral Arteries; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Cytochrome P-450 CYP4A; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Hydroxylation; In Vitro Techniques; Ion Channel Gating; Male; Mass Spectrometry; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Signal Transduction; Spectrometry, Fluorescence; Spin Labels; Superoxides; Tetraethylammonium; Vasodilation

2008
20-Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells.
    European journal of pharmacology, 2008, Jun-24, Volume: 588, Issue:1

    Topics: Annexin A5; Apoptosis; Benzimidazoles; Blotting, Western; Caspase 3; Caspase 9; Chromatin; Coloring Agents; Culture Media, Serum-Free; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondrial Membranes; Myocytes, Smooth Muscle; Propidium; Proto-Oncogene Proteins c-bcl-2; Pulmonary Artery; Tetrazolium Salts; Thiazoles

2008
Cytochrome P450 omega-hydroxylase inhibition reduces cardiomyocyte apoptosis via activation of ERK1/2 signaling in rat myocardial ischemia-reperfusion.
    European journal of pharmacology, 2008, Oct-31, Volume: 596, Issue:1-3

    Topics: Amides; Amidines; Animals; Apoptosis; Caspase 3; Cytochrome P-450 CYP4A; Enzyme Activation; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Reperfusion Injury; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Signal Transduction; Sulfones

2008
CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10 pS chloride channel in the rat thick ascending limb.
    Kidney international, 2009, Volume: 76, Issue:8

    Topics: Animals; Arachidonic Acid; Chloride Channels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Hydroxyeicosatetraenoic Acids; Hydroxylation; In Vitro Techniques; Indomethacin; Ion Channel Gating; Loop of Henle; Male; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors

2009