17-ketotrilostane has been researched along with dihydrotestosterone in 6 studies
| Studies (17-ketotrilostane) | Trials (17-ketotrilostane) | Recent Studies (post-2010) (17-ketotrilostane) | Studies (dihydrotestosterone) | Trials (dihydrotestosterone) | Recent Studies (post-2010) (dihydrotestosterone) |
|---|---|---|---|---|---|
| 6 | 0 | 1 | 9,325 | 307 | 1,517 |
| Protein | Taxonomy | 17-ketotrilostane (IC50) | dihydrotestosterone (IC50) |
|---|---|---|---|
| Plasma kallikrein | Homo sapiens (human) | 0.0031 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.54 | |
| Sex hormone-binding globulin | Homo sapiens (human) | 0.0038 | |
| Progesterone receptor | Oryctolagus cuniculus (rabbit) | 0.44 | |
| Progesterone receptor | Homo sapiens (human) | 7.3 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 0.36 | |
| Sex hormone-binding globulin | Rattus norvegicus (Norway rat) | 0.023 | |
| Androgen receptor | Homo sapiens (human) | 0.0048 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.4041 | |
| Androgen receptor | Mus musculus (house mouse) | 0.001 | |
| Mineralocorticoid receptor | Rattus norvegicus (Norway rat) | 2.1 | |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | 0.0026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McGee, JP; Shaw, PN | 1 |
| McGee, JP; Palin, KJ; Potter, C; Shaw, PN | 1 |
| Benziger, DP; Brown, RR; Stroshane, RM | 1 |
| Andrews, RS; Earnshaw, RJ; Mitchell, R; Powles, P; Robertson, WR; Robinson, DT | 1 |
| Andrews, RS; Powles, P; Robinson, DT | 1 |
| Behrend, EN; Boothe, DM; Lee, HP; McGraw, AL; Whitley, EM | 1 |
6 other study(ies) available for 17-ketotrilostane and dihydrotestosterone
| Article | Year |
|---|---|
The pharmacokinetics of trilostane and ketotrilostane in an interconverting system in the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Dihydrotestosterone; Male; Oxidative Phosphorylation Coupling Factors; Rats; Rats, Inbred Strains | 1992 |
High-performance liquid chromatographic analysis of trilostane and ketotrilostane in rat plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Dihydrotestosterone; Rats; Spectrophotometry, Ultraviolet | 1991 |
High-performance liquid chromatographic assay for trilostane and its major metabolite, 17-ketotrilostane, in human plasma.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Dihydrotestosterone; Humans; Time Factors | 1985 |
The bioavailability and metabolism of trilostane in normal subjects, a comparative study using high pressure liquid chromatographic and quantitative cytochemical assays.
Topics: Adult; Biological Availability; Chromatography, High Pressure Liquid; Dihydrotestosterone; Histocytochemistry; Humans; Male; Reference Values | 1984 |
Determination of trilostane and ketotrilostane in human plasma by high-performance liquid chromatography.
Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dihydrotestosterone; Gas Chromatography-Mass Spectrometry; Humans | 1984 |
Determination of the concentrations of trilostane and ketotrilostane that inhibit ex vivo canine adrenal gland synthesis of cortisol, corticosterone, and aldosterone.
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Aldosterone; Animals; Corticosterone; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hydrocortisone; In Vitro Techniques; Potassium | 2011 |