17-ketosteroids has been researched along with androstan-17-one* in 1 studies
1 other study(ies) available for 17-ketosteroids and androstan-17-one
Article | Year |
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Control of obesity in Avy/a mice by 5alpha-androstan-17-one.
Treating VY/WfL-Avy/a mice with 5 alpha-androston-17-one, a mammalian glucose-6-phosphate dehydrogenase inhibitor, prevented the mice from becoming obese. The weight difference between treated and control Avy/a mice was mainly due to a decreased accumulation of triacylglycerol. The compound did not suppress appetite, had no detectable toxicity and did not affect the lipogenesis rates in the liver and carcass. The weight-controlling effect of 5alpha-androstan-17-one in Avy/a mice was reversible upon withdrawal of treatment. Topics: 17-Ketosteroids; Androstanes; Animals; Female; Glucosephosphate Dehydrogenase; Liver; Male; Mice; Mice, Inbred A; Obesity; Triglycerides | 1978 |