17-ketosteroids has been researched along with 11-ketoetiocholanolone* in 3 studies
3 other study(ies) available for 17-ketosteroids and 11-ketoetiocholanolone
| Article | Year |
|---|---|
Urinary 17-ketosteroids in cystic fibrosis.
Topics: 17-Ketosteroids; Adolescent; Androsterone; Child; Child, Preschool; Cystic Fibrosis; Etiocholanolone; Female; Humans; Infant; Infant, Newborn; Male | 1981 |
Effect of dexamethasone and ACTH on the secretion pattern of fractionated 17-ketosteroids in hirsutism.
Urinary steroid fractionations of 17-ketosteroids were carried out in 3 normally-ovulating young women and in 2 women with hirsutism. Dehydroepiandrosterone, aetiocholanolone, androsterone, 11 beta-hydroxyaetiocholanolone, 11 beta-hydroxyandrosterone, 11-oxoaetiocholanolone and 11-oxondrosterone were determined quantitatively by paper chromatography. Both patients had decreased levels of 11-deoxy and 11-oxy-17-ketosteroids compared with the normals. The ready suppression of 11-oxy-17-ketosteroids and the poor suppression of 11-deoxy-17-ketosteroids by dexamethasone in both patients suggests an ovarian origin of 11-deoxy-17-ketosteroids. Supporting evidence for an ovarian origin in Case 1 was furnished by the poor suppression of testosterone by dexamethasone and lack of response to ACTH stimulation of the adrenal glands. The presented data emphasize that the precursor of 11-deoxy-17-ketosteroids of ovarian origin, possibly testosterone, may well be the cause of hirsutism in both patients. Topics: 17-Ketosteroids; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Adult; Androsterone; Dehydroepiandrosterone; Dexamethasone; Etiocholanolone; Female; Hirsutism; Humans; Ovary | 1979 |
Laboratory medicine. Series on clinical testing. 2. Fractionation of urinary ketosteroids. Procedure and clinical significance.
Ketosteroids, the excretory metabolities of adrenal and gonadal steroids, can be analyzed individually in urine by a simple extraction procedure followed by separation and quantitation by the use of gas/liquid chromatography. The ketosteroids quantitatively detected by the technique are androsterone, etiocholanolone, dehydroepiandrosterone, 11-hydroxyandrosterone, 11-hydroxyetiocholanolone, 11-ketandrosterone, and 11-ketoetiocholanolone. Other steroid metabolities detected are pregnanediol, pregnanetriol, delta5-pregnenetriol, and 11-ketopregnanetriol. In comparison with concentrations of these steroids observed in urine specimens collected from healthy individuals, abnormal results occur in specimens from patients with testicular disease, Cushing's syndrome, adrenal hyperplasia, and several types of female hirsutism. Characteristic profiles for each of these diseases are presented. Topics: 11-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Androsterone; Chemical Fractionation; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Hirsutism; Humans; Ketosteroids; Male; Pregnanediol; Pregnanetriol; Pregnenes | 1978 |