17-hydroxywortmannin has been researched along with px-866 in 1 studies
| Studies (17-hydroxywortmannin) | Trials (17-hydroxywortmannin) | Recent Studies (post-2010) (17-hydroxywortmannin) | Studies (px-866) | Trials (px-866) | Recent Studies (post-2010) (px-866) |
|---|---|---|---|---|---|
| 15 | 0 | 1 | 35 | 8 | 25 |
| Protein | Taxonomy | 17-hydroxywortmannin (IC50) | px-866 (IC50) |
|---|---|---|---|
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | 0.088 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 3.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cinque, M; Gaydos, C; Hollander, I; Kaplan, J; Lucas, J; Tischler, M; Toral-Barza, L; Young, M; Yu, K; Zask, A | 1 |
1 other study(ies) available for 17-hydroxywortmannin and px-866
| Article | Year |
|---|---|
Synthesis and structure-activity relationships of ring-opened 17-hydroxywortmannins: potent phosphoinositide 3-kinase inhibitors with improved properties and anticancer efficacy.
Topics: Androstadienes; Animals; Antineoplastic Agents; Benzopyrans; Cell Line, Tumor; Crystallography, X-Ray; Indenes; Mice; Mice, Nude; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Solubility; Stereoisomerism; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2008 |