17-hydroxy-4-7-10-13-15-19-docosahexaenoic-acid and tris(2-carboxyethyl)phosphine
17-hydroxy-4-7-10-13-15-19-docosahexaenoic-acid has been researched along with tris(2-carboxyethyl)phosphine* in 1 studies
Other Studies
1 other study(ies) available for 17-hydroxy-4-7-10-13-15-19-docosahexaenoic-acid and tris(2-carboxyethyl)phosphine
Article | Year |
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Gram scale synthesis of specialized pro-resolving mediator 17(S)-HDHA using lipoxygenase enhanced by water-soluble reducing agent TCEP.
17(S)-Hydroxy docosahexaenoic acid (17(S)-HDHA) is a specialized pro-resolving mediator. The oxidation of docosahexaenoic acid (DHA) to 17(S)-HDHA using soybean lipoxygenase was accomplished in the presence of the reducing agent TCEP in high yield and high enantio excess. We demonstrated application of this strategy to the synthesis of other fatty acids and to gram scale synthesis of 17(S)-HDHA. Topics: Borohydrides; Dithiothreitol; Docosahexaenoic Acids; Glycine max; Linolenic Acids; Lipoxygenase; Oxidation-Reduction; Phosphines; Reactive Oxygen Species; Solubility; Stereoisomerism; Water | 2016 |