17-ethynyl-5-estrane-3,17-diol has been researched along with norethindrone in 4 studies
*Norethindrone: A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for CONTRACEPTION. [MeSH]
*Norethindrone: A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for CONTRACEPTION. [MeSH]
| Studies (17-ethynyl-5-estrane-3,17-diol) | Trials (17-ethynyl-5-estrane-3,17-diol) | Recent Studies (post-2010) (17-ethynyl-5-estrane-3,17-diol) | Studies (norethindrone) | Trials (norethindrone) | Recent Studies (post-2010) (norethindrone) |
|---|---|---|---|---|---|
| 5 | 0 | 1 | 4,295 | 884 | 303 |
| Protein | Taxonomy | 17-ethynyl-5-estrane-3,17-diol (IC50) | norethindrone (IC50) |
|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | 0.808 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.433 | |
| Progesterone receptor | Homo sapiens (human) | 0.0032 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.433 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.0711 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.433 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.433 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.433 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 4.537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, GF; Curts, SW; Wren, DL | 1 |
| García, GA; Garza-Flores, J; Menjívar, M; Pérez-Palacios, G; Vilchis, F | 1 |
| Angeles, A; Chávez, B; García, GA; Pérez, AE; Pérez-Palacios, G; Vilchis, F | 1 |
| Jordan, N; Loo, JC; Menzies, JA; Watanabe, H | 1 |
4 other study(ies) available for 17-ethynyl-5-estrane-3,17-diol and norethindrone
| Article | Year |
|---|---|
Synthesis of 5 beta,17 alpha-19-norpregn-20-yne-3 beta,17-diol and of 5 beta,17 alpha-19-norpregn-20-yne-3 alpha,17-diol, human metabolites of norethindrone.
Topics: Humans; Molecular Structure; Norethindrone; Norethynodrel | 1991 |
A-ring reduction enhances the antigonadotropic potency of norethisterone.
Topics: Animals; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Isomerism; Luteinizing Hormone; Male; Norethindrone; Norethynodrel; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1986 |
Evidence that a non-aromatizable metabolite of norethisterone induces estrogen-dependent pituitary progestin receptors.
Topics: Animals; Cytosol; Estrogens; Female; Kinetics; Molecular Conformation; Norethindrone; Norethynodrel; Organ Size; Ovariectomy; Oxidation-Reduction; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Receptors, Progesterone; Stereoisomerism; Uterus | 1986 |
HPLC-RIA of a metabolite of norethindrone in human plasma, 17 alpha-ethinyl-5 beta-estrane-3 alpha, 17 beta-diol, following conjugate hydrolysis.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrolysis; Norethindrone; Norethynodrel; Radioimmunoassay | 1983 |