Page last updated: 2024-09-05

17 alpha-hydroxyprogesterone caproate and norethindrone

17 alpha-hydroxyprogesterone caproate has been researched along with norethindrone in 12 studies

Compound Research Comparison

Studies
(17 alpha-hydroxyprogesterone caproate)
Trials
(17 alpha-hydroxyprogesterone caproate)
Recent Studies (post-2010)
(17 alpha-hydroxyprogesterone caproate)
Studies
(norethindrone)
Trials
(norethindrone)
Recent Studies (post-2010) (norethindrone)
517882514,295884303

Protein Interaction Comparison

ProteinTaxonomy17 alpha-hydroxyprogesterone caproate (IC50)norethindrone (IC50)
Estrogen receptorHomo sapiens (human)0.808
Glucocorticoid receptorHomo sapiens (human)0.433
Progesterone receptorHomo sapiens (human)0.0032
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.433
Androgen receptorRattus norvegicus (Norway rat)0.0711
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.433
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.433
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.433
Sodium-dependent serotonin transporterHomo sapiens (human)4.537

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kollman, PA; Lee, DL; Marsh, FJ; Wolff, ME1
Fujimoto, J; Fujita, H; Nakata, Y; Okada, H1
Bruen, JA; Hick, JF; Kurland, LT; Noller, KL; O'Fallon, WM; Resseguie, LJ1
Bokhman, IaV; Tkeshelashvili, VT; VishnevskiÄ­, AS1
Rodriguez, L; Schindler, C1
Pavlovich, T; Schindler, C1
Schindler, C1
Schindler, C; Schober, J1
Sang, GW1
Koetsawang, S1
Giwa-Osagie, OF1

Reviews

4 review(s) available for 17 alpha-hydroxyprogesterone caproate and norethindrone

ArticleYear
Pharmacodynamic effects of once-a-month combined injectable contraceptives.
    Contraception, 1994, Volume: 49, Issue:4

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Algestone Acetophenide; China; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Estradiol; Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Latin America; Medroxyprogesterone Acetate; Norethindrone

1994
Once-a-month injectable contraceptives: efficacy and reasons for discontinuation.
    Contraception, 1994, Volume: 49, Issue:4

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Algestone Acetophenide; Clinical Trials, Phase III as Topic; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Estradiol; Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Medroxyprogesterone Acetate; Multicenter Studies as Topic; Norethindrone; Randomized Controlled Trials as Topic

1994
Metabolic effects of once-a-month combined injectable contraceptives. The World Health Organization Task Force on Long-Acting Systemic Agents for Fertility Regulation, Geneva, Switzerland.
    Contraception, 1994, Volume: 49, Issue:5

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Algestone Acetophenide; Carbohydrate Metabolism; Contraceptive Agents, Female; Estradiol; Female; Hemostasis; Humans; Hydroxyprogesterones; Injections; Lipid Metabolism; Medroxyprogesterone Acetate; Norethindrone

1994
Facts about once-a-month injectable contraceptives: memorandum from a WHO meeting.
    Bulletin of the World Health Organization, 1993, Volume: 71, Issue:6

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Animals; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Estradiol; Estrogen Antagonists; Estrogens, Conjugated (USP); Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Medroxyprogesterone Acetate; Norethindrone; World Health Organization

1993

Other Studies

8 other study(ies) available for 17 alpha-hydroxyprogesterone caproate and norethindrone

ArticleYear
Quantitative relationships between steroid structure and binding to putative progesterone receptors.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:9

    Topics: Androstenes; Animals; Guinea Pigs; Humans; Hydroxyprogesterones; Protein Binding; Rabbits; Receptors, Progesterone; Sheep; Steroids; Structure-Activity Relationship

1977
[Hormone dependency and progestogen therapy in the treatment of endometrial cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:10

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Cell Division; Female; Humans; Hydroxyprogesterones; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasms, Hormone-Dependent; Norethindrone; Tamoxifen; Tumor Stem Cell Assay; Uterine Neoplasms

1987
Congenital malformations among offspring exposed in utero to progestins, Olmsted County, Minnesota, 1936-1974.
    Fertility and sterility, 1985, Volume: 43, Issue:4

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Abnormalities, Drug-Induced; Ethisterone; Female; Fetal Death; Humans; Hydroxyprogesterones; Infant, Newborn; Male; Maternal-Fetal Exchange; Medroxyprogesterone; Minnesota; Norethindrone; Pregnancy; Prenatal Exposure Delayed Effects; Progesterone; Progestins

1985
[Planning of the treatment of atypical hyperplasia of the endometrium in patients with uterine myoma].
    Voprosy onkologii, 1984, Volume: 30, Issue:3

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Adult; Age Factors; Chlormadinone Acetate; Combined Modality Therapy; Contraceptives, Oral, Combined; Dilatation and Curettage; Drug Combinations; Drug Therapy, Combination; Endometrial Hyperplasia; Ethynodiol Diacetate; Female; Humans; Hydroxyprogesterones; Leiomyoma; Mestranol; Middle Aged; Norethindrone; Time Factors; Uterine Neoplasms

1984
[Comparative studies of the effect on the in vitro growth of endometrial cancers of hydroxyprogesterone caproate, norethisterone acetate and D-norgestrel].
    Zentralblatt fur Gynakologie, 1984, Volume: 106, Issue:7

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Cells, Cultured; Drug Evaluation, Preclinical; Drug Resistance; Female; Humans; Hydroxyprogesterones; Norethindrone; Norethindrone Acetate; Norgestrel; Uterine Neoplasms

1984
[Comparison of the results of gestagen therapy of cancer of the corpus uteri with a preliminary study of tumor cell culture sensitivity to the preparations].
    Voprosy onkologii, 1982, Volume: 28, Issue:3

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Cells, Cultured; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Female; Humans; Hydroxyprogesterones; Norethindrone; Norgestrel; Progesterone Congeners; Uterine Neoplasms

1982
[Use of gestagens to control in vitro growth of endometrial carcinoma (author's transl)].
    Zentralblatt fur Gynakologie, 1981, Volume: 103, Issue:5

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Cells, Cultured; Drug Resistance; Female; Humans; Hydroxyprogesterones; Norethindrone; Norgestrel; Progestins; Uterine Neoplasms

1981
[Results obtained from gestagen treatment of patients for endometrial carcinoma, with particular reference to results obtained from in vitro tests before treatment (author's transl)].
    Zentralblatt fur Gynakologie, 1981, Volume: 103, Issue:12

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Drug Resistance; Female; Humans; Hydroxyprogesterones; Neoplasm Staging; Norethindrone; Norethindrone Acetate; Norgestrel; Uterine Neoplasms

1981