17 alpha-hydroxyprogesterone caproate has been researched along with ketoconazole in 2 studies
| Studies (17 alpha-hydroxyprogesterone caproate) | Trials (17 alpha-hydroxyprogesterone caproate) | Recent Studies (post-2010) (17 alpha-hydroxyprogesterone caproate) | Studies (ketoconazole) | Trials (ketoconazole) | Recent Studies (post-2010) (ketoconazole) |
|---|---|---|---|---|---|
| 517 | 88 | 251 | 6,202 | 706 | 1,269 |
| 517 | 88 | 251 | 149 | 0 | 120 |
| Protein | Taxonomy | 17 alpha-hydroxyprogesterone caproate (IC50) | ketoconazole (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Homo sapiens (human) | 2.6 | |
| 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | Homo sapiens (human) | 0.34 | |
| 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | Mus musculus (house mouse) | 0.36 | |
| Bile salt export pump | Homo sapiens (human) | 3.44 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens (human) | 1.5811 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 6.7 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 4.6771 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.2303 | |
| Steroid 21-hydroxylase | Homo sapiens (human) | 6.655 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 0.06 | |
| Aromatase | Homo sapiens (human) | 1.4111 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 2.0802 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 5.425 | |
| Cholesterol side-chain cleavage enzyme, mitochondrial | Rattus norvegicus (Norway rat) | 3.32 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 1.067 | |
| Cytochrome P450 2A2 | Rattus norvegicus (Norway rat) | 0.456 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 0.38 | |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 0.4519 | |
| Translocator protein | Rattus norvegicus (Norway rat) | 3.76 | |
| Cytochrome P450 7A1 | Rattus norvegicus (Norway rat) | 1.2975 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 0.5179 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 3.8 | |
| Thromboxane-A synthase | Homo sapiens (human) | 2.165 | |
| Gonadotropin-releasing hormone receptor | Rattus norvegicus (Norway rat) | 2 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.531 | |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.0078 | |
| Cytochrome P450 4F2 | Homo sapiens (human) | 1.6 | |
| 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | Homo sapiens (human) | 0.4144 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.9036 | |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | 0.19 | |
| Cytochrome P450 7A1 | Mus musculus (house mouse) | 1.2975 | |
| Lanosterol 14-alpha demethylase | Rattus norvegicus (Norway rat) | 0.083 | |
| Epoxide hydrolase 1 | Homo sapiens (human) | 0.04 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.774 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.2535 | |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.04 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.014 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
1 review(s) available for 17 alpha-hydroxyprogesterone caproate and ketoconazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 other study(ies) available for 17 alpha-hydroxyprogesterone caproate and ketoconazole
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |