17-alpha-hydroxyprogesterone and pregnenolone

17-alpha-hydroxyprogesterone has been researched along with pregnenolone in 97 studies

Research

Studies (97)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (38.14)	18.7374
1990's	26 (26.80)	18.2507
2000's	22 (22.68)	29.6817
2010's	8 (8.25)	24.3611
2020's	4 (4.12)	2.80

Authors

Authors	Studies
Kollman, PA; Lee, DL; Marsh, FJ; Wolff, ME	1
Dunn, WJ; Grigoras, S; Koehler, MG	1
Chapman, D; Jain, AN; Koile, K	1
Good, AC; Peterson, SJ; Richards, WG	1
Good, AC; Richards, WG; So, SS	1
Platt, DE; Silverman, BD	1
Crippen, GM	1
Karplus, M; So, SS	1
Hamprecht, FA; Kubinyi, H; Mietzner, T	1
Strassburg, CP; Tukey, RH	1
Clementi, S; Cruciani, G; McLay, I; Pastor, M; Pickett, S	1
Baumann, K; Stiefl, N	1
Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H	1
Higashiura, K; Kotani, T	1
Bohl, CE; Chang, C; Chen, J; Dalton, JT; Miller, DD; Mohler, ML; Swaan, PW	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N	1
Bellavance, E; Luu-The, V; Poirier, D	1
Babalola, GO; Shapiro, BH	1
Li, PS	2
Laskey, JW; Phelps, PV	1
Roby, KF; Terranova, PF	1
Lorence, MC; Mason, JI; Murry, BA; Trant, JM	1
Armstrong, DT; Calaresu, FR; Morley, P	1
Dhont, M; Hinting, A; Serreyn, R; Vandekerckhove, D; Vanluchene, E	1
Aida, K; Barry, TP; Hanyu, I; Okumura, T	1
Adamo, MV; Balducci, R; Boscherini, B; Cives, C; Mangiantini, A; Toscano, V	1
Canario, AV; Scott, AP	1
Balm, PH; Lambert, JD; Wendelaar Bonga, SE	1
Fenske, M	1
Deslypere, JP; Vermeulen, A	1
Ali, SA; Lambert, JG; Schoonen, WG; Van den Hurk, R; Van Oordt, PG	1
Benais, JP; Bonete, R; Dreux, C; Fiet, J; Gourmel, B; Gueux, B; Lacroix, C; Villette, JM	1
Claus, M; Schöneshöfer, M	1
Dufau, ML; Knox, GF	1
Chambaz, EM; Cochet, C; Feige, JJ	1
Donaldson, A; Jeffcoate, SL; O'Shaughnessy, PJ; Pearce, S; Sufi, SB	1
Aida, K; Asahina, K; Hibiya, T; Suzuki, K; Tamaoki, B	1
Gower, DB; Kwan, TK; Taylor, NF; Watson, D	1
Banerjee, S; Mahato, SB; Podder, S	1
Benraad, TJ; Hofman, JA; Kloppenborg, PW; Smals, AG; Weusten, JJ	1
Koyle, MA; Lemmi, C; Rajfer, J; Sikka, SC	1
Makino, K; Miura, K; Ojima, M; Okuyama, M; Sasano, N; Yasuda, K	1
Goldring, NB; Orly, J	1
Belanger, A; Chen, YD; Gibori, G; Khan, I	1
Forsberg, JG; Tenenbaum, A	1
Corcelle-Cerf, F; Kolanowski, J; Lambert, F; Lammerant, J	1
Apter, D; Perheentupa, J; Voutilainen, R	1
Bermúdez, JA; Gómez, S; González Garza, MT; Herrera, J; Montalvo, I; Sotelo, A	1
Corda, R; Faedda, A; Fanni, V; Loche, S; Nurchi, AM; Pintor, C	1
Bhatia, K; Mead, RA; Ravindra, R	1
Antila, E; Leikola, A; Tähkä, S	1
D'Ambrogio, G; Facchini, V; Genazzani, AR; Inaudi, P; Massafra, C	1
Ekholm, C; Hedin, L; Hillensjö, T	1
Eriksson, CJ; Härkönen, M; Leinonen, P; Widenius, TV; Ylikahri, RH	1
Greenwald, GS; Kim, I	1
Greenwald, GS; Silavin, SL	1
Kagawa, N; Katagiri, M; Waterman, MR	1
Ahn, RS; Kwon, HB	1
Ahn, RS; Bai, DG; Ko, SK; Kwon, HB; Yoon, YD	1
Goff, AK; Leduc, S; Poitras, P; Vaillancourt, D	1
Ahn, RS; Im, WB; Kim, K; Kwon, HB; Lee, CC; Lee, WK	1
Estabrook, RW; Mason, JI; Swart, AC; Swart, P; Waterman, MR	1
Acosta, CK; Kim, HK; Rao, PN	1
Adachi, S; Ando, Y; Fujii, E; Iioka, H; Morikawa, H; Morimoto, K; Okamura, Y; Oku, M; Otsuki, T	1
Fostier, A; Gaignon, JL; Mugnier, C	1
Achstetter, T; Cauet, G; Degryse, E; Spagnoli, R	1
Beaujean, D; Do-Rego, JL; Leprince, J; Luu-The, V; Mensah-Nyagan, AG; Pelletier, G; Tonon, MC; Vaudry, H	1
Barrantes, FJ; Bouzat, C; Garbus, I	1
Cánepa, DF; Cigorraga, SB; Meroni, SB; Pellizzari, EH	1
Bouchard, C; Gagnon, J; Leon, AS; Rankinen, T; Rao, DC; Skinner, JS; Ukkola, O; Wilmore, JH	1
Dorner, M; Falk, W; Schölmerich, J; Straub, RH; Vogl, D	1
Auchus, RJ; LeHoux, JG; Mathieu, AP	1
Auchus, RJ; Flück, CE; Miller, WL	1
HECHTER, O; JACOBSEN, RP; JEANLOZ, RW; LEVY, H; PINCUS, G; SCHENKER, V	1
LANTHIER, A; SANDOR, T	1
EIK-NES, KB; HAGEN, AA	1
HAGERMAN, D; SOBREVILLA, L; VILLEE, C	1
Fujimoto, S; Nomura, E; Sugawara, T	1
Azziz, R; Boots, LS; Moran, C; Reyna, R	1
Bloch, E; Kostellow, A; Morrill, GA; Schatz, F	1
Bunker, AM; Kushnir, MM; Meikle, AW; Owen, WE; Pattison, EG; Roberts, WL; Rockwood, AL	1
Bunker, AM; Kushnir, MM; Meikle, AW; Owen, WE; Pattison, EG; Phanslkar, AR; Roberts, WL; Rockwood, AL; Sandrock, T; Terry, AH	1
Dacou-Voutetakis, A; Dracopoulou, M; Magnisali, P; Mataragas, M; Moutsatsou, P	1
Chen, W; Sheu, HM; Tsai, JC; Tsai, SJ; Zouboulis, CC	1
Aketo, T; Nakagawa, S; Tachikawa, E; Yamato, S; Yamazaki, N	1
Aronsson, B; Bergquist, J; Kushnir, MM; Sandstedt, P; Söndergaard, HP	1
Arlt, W; de Herder, WW; de Jong, FH; Feelders, RA; Hofland, J; Hofland, LJ; Steenbergen, J; Taylor, AE; van der Pas, R; van Koetsveld, PM	1
DeVore, NM; Petrunak, EM; Porubsky, PR; Scott, EE	1
Bertini, ES; Biagini, G; Cusmai, R; Gecz, J; Giannone, G; Lucchi, C; Rustichelli, C; Specchio, N; Terracciano, A; Trivisano, M; Ubertini, GM; Vigevano, F	1
Borba, LA; Canisso, IF; Curcio, BR; Feijó, LS; Müller, V; Nogueira, CEW; Toribio, RE	1
Bonnet, F; Bouzerara, A; Ferecatu, I; Fournier, T; Fraichard, C; Garnier, A; Gerbaud, P; Guibourdenche, J; Hébert-Schuster, M; Hernandez, I; Trabado, S	1
Cao, B; Gong, C; Li, W; Liang, X; Liu, M; Meng, X; Qin, M; Su, C; Wei, L; Wu, D	1
Akıncı, E; Bal, C; Erel, Ö; Eser, F; Güner, R; Hasanoglu, İ; Kalem, AK; Kayaaslan, B; Sezer, S; Yılmaz, G	1
Babayev, E; Duncan, FE; Shea, LD; Woodruff, TK; Xu, M	1
Bouty, A; Dijoud, F; Ecochard, R; Mallet, D; Mouriquand, P; Mure, PY; Plotton, I; Pourquet, A; Renault, L; Rigaud, C; Roucher, F; Sanlaville, D; Teoli, J	1

Reviews

2 review(s) available for 17-alpha-hydroxyprogesterone and pregnenolone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Fetal Leydig cell culture--an in vitro system for the study of trophic hormone and GnRH receptors and actions. Journal of steroid biochemistry, 1985, Volume: 23, Issue:5B Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Histocytochemistry; Hydroxyprogesterones; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Pregnancy; Pregnenolone; Rats; Steroid 17-alpha-Hydroxylase; Testosterone; Time Factors	1985

Article

Year

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

Annual review of pharmacology and toxicology, 2000, Volume: 40

Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Fetal Leydig cell culture--an in vitro system for the study of trophic hormone and GnRH receptors and actions.

Journal of steroid biochemistry, 1985, Volume: 23, Issue:5B

Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Histocytochemistry; Hydroxyprogesterones; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Pregnancy; Pregnenolone; Rats; Steroid 17-alpha-Hydroxylase; Testosterone; Time Factors

1985

Trials

2 trial(s) available for 17-alpha-hydroxyprogesterone and pregnenolone

Article	Year
Adrenocortical hyperresponsiveness to corticotropin in polycystic ovary syndrome patients with adrenal androgen excess. Fertility and sterility, 2004, Volume: 81, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperandrogenism; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Prospective Studies; Steroid 17-alpha-Hydroxylase; Testosterone	2004
Cortisol, progesterone, 17αOHprogesterone, and pregnenolone in foals born from mare's hormone-treated for experimentally induced ascending placentitis. Theriogenology, 2019, Jan-01, Volume: 123 Topics: 17-alpha-Hydroxyprogesterone; Animals; Animals, Newborn; Anti-Bacterial Agents; Clonixin; Contraceptive Agents, Female; Estradiol; Female; Horse Diseases; Horses; Hydrocortisone; Placenta Diseases; Pregnancy; Pregnenolone; Progesterone; Progestins; Random Allocation; Streptococcal Infections; Streptococcus equi; Trenbolone Acetate; Trimethoprim, Sulfamethoxazole Drug Combination	2019

Article

Year

Adrenocortical hyperresponsiveness to corticotropin in polycystic ovary syndrome patients with adrenal androgen excess.

Fertility and sterility, 2004, Volume: 81, Issue:1

Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperandrogenism; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Prospective Studies; Steroid 17-alpha-Hydroxylase; Testosterone

2004

Cortisol, progesterone, 17αOHprogesterone, and pregnenolone in foals born from mare's hormone-treated for experimentally induced ascending placentitis.

Theriogenology, 2019, Jan-01, Volume: 123

Topics: 17-alpha-Hydroxyprogesterone; Animals; Animals, Newborn; Anti-Bacterial Agents; Clonixin; Contraceptive Agents, Female; Estradiol; Female; Horse Diseases; Horses; Hydrocortisone; Placenta Diseases; Pregnancy; Pregnenolone; Progesterone; Progestins; Random Allocation; Streptococcal Infections; Streptococcus equi; Trenbolone Acetate; Trimethoprim, Sulfamethoxazole Drug Combination

2019

Other Studies

93 other study(ies) available for 17-alpha-hydroxyprogesterone and pregnenolone

Article	Year
Quantitative relationships between steroid structure and binding to putative progesterone receptors. Journal of medicinal chemistry, 1977, Volume: 20, Issue:9 Topics: Androstenes; Animals; Guinea Pigs; Humans; Hydroxyprogesterones; Protein Binding; Rabbits; Receptors, Progesterone; Sheep; Steroids; Structure-Activity Relationship	1977
The role of solvent-accessible surface area in determining partition coefficients. Journal of medicinal chemistry, 1987, Volume: 30, Issue:7 Topics: Diffusion; Solubility; Solvents; Structure-Activity Relationship	1987
Compass: predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark. Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15 Topics: Algorithms; Models, Molecular; Models, Statistical; Molecular Conformation; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Surface Properties; Transcortin	1994
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods. Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20 Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship	1993
Structure-activity relationships from molecular similarity matrices. Journal of medicinal chemistry, 1993, Feb-19, Volume: 36, Issue:4 Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin	1993
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11 Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone	1996
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data. Journal of medicinal chemistry, 1997, Sep-26, Volume: 40, Issue:20 Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin	1997
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 1. Method and validations. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Algorithms; Models, Chemical; Molecular Structure; Neural Networks, Computer; Protein Binding; Static Electricity; Steroids; Structure-Activity Relationship; Transcortin	1997
Three-dimensional quantitative similarity-activity relationships (3D QSiAR) from SEAL similarity matrices. Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14 Topics: Drug Design; Least-Squares Analysis; Molecular Conformation; Steroids; Structure-Activity Relationship; Transcortin	1998
GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors. Journal of medicinal chemistry, 2000, Aug-24, Volume: 43, Issue:17 Topics: Butyrophenones; Enzyme Inhibitors; Glucose; Models, Molecular; Phosphorylases; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Software; Steroids; Transcortin	2000
Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique. Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8 Topics: Acetates; Alcohols; Algorithms; Cholinergic Agents; Hydrocarbons, Acyclic; Hydrocarbons, Aromatic; Ketones; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Receptor, Muscarinic M2; Receptors, Muscarinic; Steroids; Transcortin	2003
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22 Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts	2003
Comparative molecular active site analysis (CoMASA). 1. An approach to rapid evaluation of 3D QSAR. Journal of medicinal chemistry, 2004, May-20, Volume: 47, Issue:11 Topics: Binding Sites; Cluster Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Steroids	2004
A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor. Journal of medicinal chemistry, 2004, Jul-15, Volume: 47, Issue:15 Topics: Anilides; Heterocyclic Compounds, 3-Ring; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Nitriles; Quantitative Structure-Activity Relationship; Quinolines; Receptors, Androgen; Static Electricity; Steroids; Tosyl Compounds	2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids	2008
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23 Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity	2009
Changes in the expression of cytochrome P450c17 associated with ovarian cystic follicles. An immunocytochemical and enzymatic analysis of porcine ovaries. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 42, Issue:6 Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Female; Hydroxyprogesterones; Immunohistochemistry; Ovarian Cysts; Ovary; Pregnenolone; Progesterone; Swine; Testosterone	1992
In vitro effects of estradiol, diethylstilbestrol and tamoxifen on testosterone production by purified pig Leydig cells. The Chinese journal of physiology, 1991, Volume: 34, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Animals; Colforsin; Cyclic AMP; Diethylstilbestrol; Estradiol; Hydroxyprogesterones; Leydig Cells; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Radioimmunoassay; Swine; Tamoxifen; Testosterone	1991
Effect of cortisol on testosterone production by immature pig Leydig cells. The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Aldehyde-Lyases; Animals; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Leydig Cells; Luteinizing Hormone; Male; Pregnenolone; Steroid 17-alpha-Hydroxylase; Swine; Testosterone	1991
Effect of cadmium and other metal cations on in vitro Leydig cell testosterone production. Toxicology and applied pharmacology, 1991, Volume: 108, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Bucladesine; Cadmium; Cations; Cells, Cultured; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Hydroxycholesterols; Hydroxyprogesterones; Leydig Cells; Male; Metals; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Receptors, LH; Testosterone	1991
Effects of tumor necrosis factor-alpha in vitro on steroidogenesis of healthy and atretic follicles of the rat: theca as a target. Endocrinology, 1990, Volume: 126, Issue:5 Topics: 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Cells, Cultured; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydroxycholesterols; Hydroxyprogesterones; Kinetics; Ovarian Follicle; Oxygen; Pregnenolone; Proestrus; Progesterone; Rats; Recombinant Proteins; Steroids; Theca Cells; Tumor Necrosis Factor-alpha	1990
Human 3 beta-hydroxysteroid dehydrogenase/delta 5----4isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids. Endocrinology, 1990, Volume: 126, Issue:5 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Androstenedione; Base Sequence; Dehydroepiandrosterone; DNA; Female; Gene Expression; Humans; Hydroxyprogesterones; Immunoblotting; Isomerases; Microsomes; Molecular Sequence Data; Multienzyme Complexes; NAD; Placenta; Pregnancy; Pregnenolone; Progesterone; Progesterone Reductase; Steroid Isomerases; Transfection; Tumor Cells, Cultured	1990
Site at which ovarian nerve extracts inhibit thecal androgen production. Molecular and cellular endocrinology, 1990, May-28, Volume: 71, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Androgens; Androstenedione; Animals; Cells, Cultured; Cyclic AMP; Estradiol; Estrone; Female; Hydroxyprogesterones; Luteinizing Hormone; Ovary; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Swine; Testosterone; Theca Cells; Tissue Extracts	1990
Steroid determinations in human ovarian follicular fluid using capillary gas chromatography. Journal of steroid biochemistry, 1990, Volume: 35, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Adult; Chromatography, Gas; Estradiol; Estrogens; Estrone; Female; Follicular Fluid; Humans; Hydroxyprogesterones; Pregnenolone; Progesterone; Progestins	1990
The shift from C-19 to C-21 steroid synthesis in spawning male common carp, Cyprinus carpio, is regulated by the inhibition of androgen production by progestogens produced by spermatozoa. Biology of reproduction, 1990, Volume: 43, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Analysis of Variance; Androgens; Animals; Carps; Chromatography, High Pressure Liquid; Cyprinidae; Dose-Response Relationship, Drug; Feedback; Gonadotropins; Growth Hormone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progestins; Prolactin; Radioimmunoassay; Spermatozoa; Testis; Testosterone	1990
Changes in steroid pattern following acute and chronic adrenocorticotropin administration in premature adrenarche. Journal of steroid biochemistry, 1989, Volume: 32, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androstenedione; Child; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Pregnenolone; Puberty, Precocious	1989
Synthesis of 20 alpha-hydroxylated steroids by ovaries of the dab (Limanda limanda). General and comparative endocrinology, 1989, Volume: 76, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; 20-Hydroxysteroid Dehydrogenases; Animals; Female; Fishes; Hydroxyprogesterones; Male; Ovary; Pregnanes; Pregnanetriol; Pregnanolone; Pregnenolone; Radioimmunoassay	1989
Corticosteroid biosynthesis in the interrenal cells of the teleost fish, Oreochromis mossambicus. General and comparative endocrinology, 1989, Volume: 76, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Fishes; Hydroxyprogesterones; Kidney; Pregnenolone	1989
Basal and HCG-stimulated testosterone production by interstitial cells of the Mongolian gerbil (Meriones unguiculatus)--II. Influence of glucocorticosteroids and steroidal precursors. Comparative biochemistry and physiology. A, Comparative physiology, 1986, Volume: 85, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Animals; Cells, Cultured; Chorionic Gonadotropin; Dehydroepiandrosterone; Gerbillinae; Glucocorticoids; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Time Factors	1986
Intratesticular unconjugated steroids in elderly men. Journal of steroid biochemistry, 1986, Volume: 24, Issue:5 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adult; Aged; Androstane-3,17-diol; Androstenediol; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Reference Values; Steroids; Testis; Testosterone	1986
The skin of the male African catfish, Clarias gariepinus: a source of steroid glucuronides. General and comparative endocrinology, 1987, Volume: 66, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Catfishes; Dehydroepiandrosterone; Glucuronates; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Skin; Steroids; Testosterone; Tritium	1987
Simultaneous radioimmunoassay of progesterone, androst-4-enedione, pregnenolone, dehydroepiandrosterone and 17-hydroxyprogesterone in specific regions of human brain. Journal of steroid biochemistry, 1987, Volume: 28, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Brain Chemistry; Cross Reactions; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Pregnenolone; Progesterone; Radioimmunoassay; Tissue Distribution	1987
Multiple-sites of inhibition by intravenous metyrapone of human adrenal steroidogenesis. Acta endocrinologica, 1985, Volume: 109, Issue:3 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Corticosterone; Cortodoxone; Humans; Hydrocortisone; Hydroxyprogesterones; Infusions, Parenteral; Male; Metyrapone; Pregnenolone; Progesterone	1985
Type beta transforming growth factor is a potent modulator of differentiated adrenocortical cell functions. Biochemical and biophysical research communications, 1986, Sep-14, Volume: 139, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Angiotensin II; Animals; Cattle; DNA Replication; Hydroxyprogesterones; Peptides; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Transforming Growth Factors	1986
Site of gossypol inhibition of steroidogenesis in purified mouse Leydig cells. Journal of steroid biochemistry, 1986, Volume: 25, Issue:5A Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Bucladesine; Gossypol; Hydroxycholesterols; Hydroxyprogesterones; Leydig Cells; Luteinizing Hormone; Male; Mice; Pregnenolone; Progesterone; Testosterone	1986
Relationship between the structures and steroidogenic functions of the testes of the urohaze-goby (Glossogobius olivaceus). General and comparative endocrinology, 1985, Volume: 57, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Androstane-3,17-diol; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Etiocholanolone; Fishes; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone	1985
Gas chromatographic-mass spectrometric study of metabolites of C21 and C19 steroids in neonatal porcine testicular microsomes. The Biochemical journal, 1985, May-01, Volume: 227, Issue:3 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androstenediol; Androstenols; Animals; Animals, Newborn; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Hydroxyprogesterones; Male; Microsomes; Pregnanes; Pregnenolone; Progesterone; Swine; Testis	1985
Oxidative side-chain and ring fission of pregnanes by Arthrobacter simplex. The Biochemical journal, 1988, Nov-01, Volume: 255, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Arthrobacter; Cortodoxone; Hydroxyprogesterones; Magnetic Resonance Spectroscopy; Models, Biological; Oxidation-Reduction; Pregnanes; Pregnenolone; Progesterone	1988
Early time sequence in pregnenolone metabolism to testosterone in homogenates of human and rat testis. Endocrinology, 1987, Volume: 120, Issue:5 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aged; Animals; Chromatography, High Pressure Liquid; Humans; Hydroxyprogesterones; Kinetics; Male; Middle Aged; NAD; NADP; Pregnenolone; Progesterone; Rats; Testis; Testosterone	1987
Cyclosporine inhibits testosterone biosynthesis in the rat testis. Endocrinology, 1987, Volume: 121, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Cyclosporins; Hydroxyprogesterones; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Testis; Testosterone	1987
An adrenocortical tumor secreting weak mineralocorticoids. Endocrinologia japonica, 1987, Volume: 34, Issue:1 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; Adrenal Cortex Neoplasms; Adult; Carcinoma; Corticosterone; Desoxycorticosterone; Female; Humans; Hydroxyprogesterones; Hypertension; Mineralocorticoids; Pregnenolone; Progesterone	1987
Concerted metabolism of steroid hormones produced by cocultured ovarian cell types. The Journal of biological chemistry, 1985, Jan-25, Volume: 260, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androsterone; Animals; Cells, Cultured; Female; Follicle Stimulating Hormone; Hydroxyprogesterones; Luteinizing Hormone; Ovary; Pregnanediol; Pregnanetriol; Pregnenolone; Progestins; Rats; Rats, Inbred Strains	1985
Influence of high-density lipoprotein on estradiol stimulation of luteal steroidogenesis. Biology of reproduction, 1985, Volume: 32, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Animals; Corpus Luteum; Estradiol; Female; Hydroxyprogesterones; Lipoproteins, HDL; Pregnancy; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Testosterone	1985
Structural and functional changes in ovaries from adult mice treated with diethylstilboestrol in the neonatal period. Journal of reproduction and fertility, 1985, Volume: 73, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Diethylstilbestrol; Estrus; Female; Hydroxyprogesterones; In Vitro Techniques; Mice; Mice, Inbred Strains; Ovary; Pregnancy; Pregnenolone; Progesterone; Testosterone	1985
On the specificity of the inhibitory effect of trilostane and aminoglutethimide on adrenocortical steroidogenesis in guinea pig. Molecular and cellular endocrinology, 1984, Volume: 37, Issue:1 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cortodoxone; Dihydrotestosterone; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Male; Pregnenolone; Progesterone	1984
Benign premature adrenarche: clinical features and serum steroid levels. Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:5 Topics: 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adrenal Glands; Androgens; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Hydroxyprogesterones; Pregnenolone; Progesterone; Testosterone	1983
Modifications in the testis steroidogenic pathways in rats fed with cottonseed flour. Archives of andrology, 1984, Volume: 12, Issue:1 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androgens; Animals; Cottonseed Oil; Dehydroepiandrosterone; Diet; Gossypol; Hydroxyprogesterones; Male; Mice; Mice, Inbred Strains; Pregnenolone; Rats; Testis; Testosterone	1984
Adrenal androgens in obese boys before and after weight loss. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16, Issue:10 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Androgens; Androstenedione; Body Weight; Child; Dehydroepiandrosterone; Estradiol; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Obesity; Pregnenolone; Progesterone; Testosterone	1984
Steroid metabolism in corpora lutea of the western spotted skunk (Spilogale putorius latifrons). Journal of reproduction and fertility, 1984, Volume: 72, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Carnivora; Corpus Luteum; Dehydroepiandrosterone; Embryo Implantation, Delayed; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Mephitidae; Pregnancy; Pregnenolone; Progesterone; Testosterone	1984
Early steroid metabolism by chick blastoderm in vitro. Steroids, 1984, Volume: 43, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Blastoderm; Chick Embryo; Dehydroepiandrosterone; Estradiol; Hydroxyprogesterones; Kinetics; Pregnenolone; Progesterone; Steroids; Testosterone	1984
Impaired pregnenolone secretion after combined cyproterone acetate and ethynyl estradiol therapy in hirsute patients. Gynecologic and obstetric investigation, 1982, Volume: 14, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenedione; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Testosterone	1982
Effect of gonadotrophin releasing hormone upon the pattern of steroidogenesis in isolated preovulatory rat follicles. Acta endocrinologica, 1984, Volume: 105, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Estradiol; Female; Gonadotropin-Releasing Hormone; Gonadotropins, Equine; Hydroxyprogesterones; Luteinizing Hormone; Ovarian Follicle; Pituitary Hormone Release Inhibiting Hormones; Pituitary Hormone-Releasing Hormones; Pregnenolone; Progesterone; Rats; Testosterone	1984
Inhibition of testosterone biosynthesis by ethanol: relation to the pregnenolone-to-testosterone pathway. FEBS letters, 1984, Jul-09, Volume: 172, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Alcoholic Intoxication; Androstenedione; Animals; Ethanol; Fomepizole; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Pyrazoles; Rats; Testis; Testosterone	1984
Further studies on in vitro steroidogenesis by luteal cells from long-term hypophysectomized rats. Biology of reproduction, 1984, Volume: 30, Issue:4 Topics: 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Animals; Chorionic Gonadotropin; Corpus Luteum; Estradiol; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Hypophysectomy; Luteal Cells; Luteinizing Hormone; Pregnenolone; Progesterone; Prolactin; Rats; Testosterone	1984
Steroid production by isolated theca and granulosa cells after initiation of atresia in the hamster. Journal of reproduction and fertility, 1984, Volume: 71, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Cricetinae; Estradiol; Female; Gonadotropins, Equine; Granulosa Cells; Hydroxyprogesterones; Hypophysectomy; Immune Sera; Mesocricetus; Pregnenolone; Progesterone; Theca Cells	1984
The role of cytochrome b5 in the biosynthesis of androgens by human P450c17. Archives of biochemistry and biophysics, 1995, Mar-10, Volume: 317, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androgens; Androstenedione; Cell Membrane; Cytochrome P-450 Enzyme System; Cytochromes b5; Dehydroepiandrosterone; Escherichia coli; Humans; Hydroxyprogesterones; Kinetics; Pregnenolone; Progesterone; Recombinant Proteins; Steroid 17-alpha-Hydroxylase	1995
Relative roles of theca and granulosa cells in ovarian follicular steroidogenesis in the amphibian, Rana nigromaculata. General and comparative endocrinology, 1994, Volume: 94, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Estradiol; Female; Granulosa Cells; Hydroxyprogesterones; Oocytes; Organ Culture Techniques; Ovarian Follicle; Pituitary Gland; Pregnenolone; Progesterone; Radioimmunoassay; Ranidae; Steroids; Testosterone; Theca Cells; Tissue Extracts	1994
Steroidogenic shift by cultured ovarian follicles of Rana dybowskii at breeding season. The Journal of experimental zoology, 1993, Nov-01, Volume: 267, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Analysis of Variance; Androstenedione; Animals; Culture Techniques; Female; Hibernation; Hydroxyprogesterones; Ovarian Follicle; Pregnenolone; Progesterone; Radioimmunoassay; Ranidae; Reproduction; Seasons; Testosterone	1993
Steroid synthesis by equine conceptuses between days 7 and 14 and endometrial steroid metabolism. Domestic animal endocrinology, 1993, Volume: 10, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Analysis of Variance; Androstenedione; Anestrus; Animals; Chromatography, High Pressure Liquid; Culture Techniques; Embryo, Mammalian; Endometrium; Estradiol; Estrus; Female; Hormones; Horses; Hydroxyprogesterones; Pregnancy; Pregnenolone	1993
Changes in the activities of steroidogenic enzymes during the development of ovarian follicles in Rana nigromaculata. General and comparative endocrinology, 1993, Volume: 92, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Aromatase; Cells, Cultured; Estradiol; Female; Hydroxyprogesterones; Ovarian Follicle; Pregnenolone; Progesterone; Radioimmunoassay; Ranidae; Testosterone	1993
Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase. The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Animals; Aryl Hydrocarbon Hydroxylases; Cell Line, Transformed; Chlorocebus aethiops; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; DNA; Humans; Hydroxyprogesterones; Ketoconazole; Kidney; Kinetics; Male; Microsomes; NADP; Pregnenolone; Progesterone; Steroid 16-alpha-Hydroxylase; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Testis; Transfection	1993
Tetrapropylammonium perruthenate as a mild and efficient oxidant for sensitive steroidal alcohols. Steroids, 1993, Volume: 58, Issue:5 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alcohols; Androstenedione; Cyclic N-Oxides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hydroxyprogesterones; Ketones; Morpholines; Organometallic Compounds; Oxidants; Oxidation-Reduction; Pregnenediones; Pregnenolone; Quaternary Ammonium Compounds; Ruthenium; Steroids	1993
[A study on the maternal plasma C21 steroids concentration during pregnancy]. Nihon Sanka Fujinka Gakkai zasshi, 1996, Volume: 48, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Chromatography, High Pressure Liquid; Cortisone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnancy; Pregnenolone; Steroid 21-Hydroxylase	1996
In vitro synthesis of 17,20 beta,21-trihydroxy-4-pregnen-3-one by ovaries of turbot (Scophthalmus maximus L.) during oocyte maturation. General and comparative endocrinology, 1997, Volume: 107, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cortodoxone; Female; Flatfishes; In Vitro Techniques; Mass Spectrometry; Oocytes; Ovary; Pregnenolone; Sexual Maturation	1997
Pregnenolone metabolized to 17alpha-hydroxyprogesterone in yeast: biochemical analysis of a metabolic pathway. The Journal of steroid biochemistry and molecular biology, 1999, Dec-31, Volume: 71, Issue:5-6 Topics: 17-alpha-Hydroxyprogesterone; Amino Acid Sequence; Animals; Cattle; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Pregnenolone; Progesterone Reductase; Saccharomyces cerevisiae; Steroid 17-alpha-Hydroxylase; Steroid Isomerases	1999
The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central-type benzodiazepine receptors. Journal of neurochemistry, 2001, Volume: 76, Issue:1 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Animals; Carbolines; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Diazepam Binding Inhibitor; Dihydrotestosterone; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hydroxysteroids; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Ligands; Male; Neuroglia; Neurons; Neuropeptides; Peptide Fragments; Pregnenolone; Progesterone; Rana ridibunda; Receptors, GABA-A	2001
Steroids differentially inhibit the nicotinic acetylcholine receptor. Neuroreport, 2001, Feb-12, Volume: 12, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Aldosterone; Animals; Anti-Inflammatory Agents; Cell Line; Cortisone; Cortodoxone; Humans; Hydrocortisone; Ion Channel Gating; Kidney; Mice; Nicotinic Antagonists; Patch-Clamp Techniques; Pregnenolone; Receptors, Nicotinic; Steroids; Transfection; Water	2001
Possible involvement of ceramide in the regulation of rat Leydig cell function. The Journal of steroid biochemistry and molecular biology, 2000, Dec-31, Volume: 75, Issue:4-5 Topics: 17-alpha-Hydroxyprogesterone; Amidohydrolases; Androstenedione; Animals; Bucladesine; Ceramidases; Ceramides; Cholesterol; Chorionic Gonadotropin; Cyclic AMP; In Vitro Techniques; Interleukin-1; Leydig Cells; Male; Pregnenolone; Rats; Rats, Sprague-Dawley; Signal Transduction; Testosterone; Tumor Necrosis Factor-alpha	2000
A genome-wide linkage scan for steroids and SHBG levels in black and white families: the HERITAGE Family Study. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:8 Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Aged; Androsterone; Black People; Cohort Studies; Dihydrotestosterone; Female; Genetic Linkage; Genome, Human; Hormones; Humans; Hydrocortisone; Male; Middle Aged; Pregnenolone; Progesterone; Sex Hormone-Binding Globulin; Testosterone; White People	2002
Serum levels of pregnenolone and 17-hydroxypregnenolone in patients with rheumatoid arthritis and systemic lupus erythematosus: relation to other adrenal hormones. The Journal of rheumatology, 2003, Volume: 30, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adult; Aged; Androstenedione; Arthritis, Rheumatoid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Lupus Erythematosus, Systemic; Male; Middle Aged; Pregnenolone; Progesterone	2003
Molecular dynamics of substrate complexes with hamster cytochrome P450c17 (CYP17): mechanistic approach to understanding substrate binding and activities. Biochimica et biophysica acta, 2003, Feb-17, Volume: 1619, Issue:3 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Cricetinae; Isoenzymes; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Substrate Specificity	2003
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway. The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:8 Topics: 17-alpha-Hydroxyprogesterone; Adult; Catalysis; Dehydroepiandrosterone; Female; Humans; Kinetics; Leydig Cells; Male; Microsomes; Multienzyme Complexes; Pregnancy; Pregnanolone; Pregnenolone; Progesterone; Progesterone Reductase; Steroid 17-alpha-Hydroxylase; Steroid Isomerases; Steroids; Testis	2003
Chemical transformations of steroids by adrenal perfusion; progesterone, 17 alpha-hydroxyprogesterone, and pregn-5-en-3beta-ol-20-one. The Journal of biological chemistry, 1954, Volume: 211, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Perfusion; Pregnenolone; Progesterone; Steroids	1954
Identification of a steriod glycol produced by human ovarian slices from 17 alpha-hydroxyprogesterone. Canadian journal of biochemistry and physiology, 1961, Volume: 39 Topics: 17-alpha-Hydroxyprogesterone; Female; Glycols; Humans; Ovary; Pregnenolone; Progesterone	1961
CONVERSION OF 17-ALPHA-HYDROXYPREGNENOLONE TO 17-ALPHA-HYDROXYPROGESTERONE BY THE CANINE TESTIS IN VIVO. Biochimica et biophysica acta, 1964, May-11, Volume: 86 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androgens; Animals; Carbon Isotopes; Chorionic Gonadotropin; Chromatography; Dogs; Gonadotropins; Humans; Hydroxyprogesterones; Iliac Artery; Male; Metabolism; Pharmacology; Pregnenolone; Research; Testis; Testosterone; Tritium; Ultraviolet Rays	1964
THE METABOLISM OF PREGNENOLONE AND 17-ALPHA-HYDROXYPROGESTERONE BY HOMOGENATES OF HUMAN TERM PLACENTAS. Biochimica et biophysica acta, 1964, Dec-09, Volume: 93 Topics: 17-alpha-Hydroxyprogesterone; Carbon Isotopes; Chromatography; Female; Humans; Hydroxyprogesterones; Metabolism; Placenta; Pregnancy; Pregnenolone; Radiometry; Research	1964
Expression of enzyme associated with steroid hormone synthesis and local production of steroid hormone in endometrial carcinoma cells. The Journal of endocrinology, 2004, Volume: 180, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Aromatase; Carcinoma; Cell Line, Tumor; Cholesterol Side-Chain Cleavage Enzyme; Endometrial Neoplasms; Female; Gene Expression; Humans; Phosphoproteins; Pregnenolone; Progesterone; Reverse Transcriptase Polymerase Chain Reaction; Steroid 17-alpha-Hydroxylase; Transfection	2004
Gonadotropin stimulation of steroid synthesis and metabolism in the Rana pipiens ovarian follicle: sequential changes in endogenous steroids during ovulation, fertilization and cleavage stages. The Journal of steroid biochemistry and molecular biology, 2006, Volume: 99, Issue:2-3 Topics: 17-alpha-Hydroxyprogesterone; Acetates; Androstenedione; Animals; Blastula; Cleavage Stage, Ovum; Female; Fertilization; Gonadotropins; Male; Oocytes; Ovarian Follicle; Ovulation; Pregnanediol; Pregnanediones; Pregnenolone; Progesterone; Rana pipiens; Steroids; Subcellular Fractions	2006
Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids. Clinical chemistry, 2006, Volume: 52, Issue:8 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Child; Chromatography, Liquid; Cortodoxone; Female; Humans; Indicator Dilution Techniques; Male; Middle Aged; Pregnenolone; Reference Values; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2006
Adrenal steroid concentrations in children seven to seventeen years of age. Journal of pediatric endocrinology & metabolism : JPEM, 2007, Volume: 20, Issue:12 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Age Factors; Analysis of Variance; Androstenedione; Child; Chromatography, High Pressure Liquid; Cortodoxone; Dehydroepiandrosterone Sulfate; Female; Humans; Immunoassay; Male; Pregnenolone; Puberty; Sex Factors; Sexual Maturation; Steroids; Tandem Mass Spectrometry; Testosterone	2007
Routine method for the simultaneous quantification of 17alpha-hydroxyprogesterone, testosterone, dehydroepiandrosterone, androstenedione, cortisol, and pregnenolone in human serum of neonates using gas chromatography-mass spectrometry. Journal of chromatography. A, 2008, Oct-10, Volume: 1206, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Immunoassay; Infant, Newborn; Male; Pregnenolone; Reference Standards; Testosterone	2008
Testosterone synthesized in cultured human SZ95 sebocytes derives mainly from dehydroepiandrosterone. Experimental dermatology, 2010, Volume: 19, Issue:5 Topics: 17-alpha-Hydroxyprogesterone; Cell Line, Transformed; Cholesterol; Chorionic Gonadotropin; Colforsin; Cyclic CMP; Dehydroepiandrosterone; Dexamethasone; Female; Fibroblast Growth Factor 9; Humans; Hydroxycholesterols; Insulin; Insulin-Like Growth Factor I; Interleukin-1beta; Pregnenolone; Progesterone; Sebaceous Glands; Testosterone	2010
Simultaneous determination of pregnenolone and 17α-hydroxypregnenolone by semi-micro high-performance liquid chromatography with an immobilized cholesterol oxidase as a pre-column reactor: application to bovine adrenal fasciculata cells. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Dec-15, Volume: 878, Issue:32 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Animals; Cattle; Cells, Cultured; Cholesterol Oxidase; Enzymes, Immobilized; Linear Models; Pregnenolone; Progesterone; Sensitivity and Specificity; Zona Fasciculata	2010
Patterns of endogenous steroids in apathetic refugee children are compatible with long-term stress. BMC research notes, 2012, Jun-19, Volume: 5 Topics: 17-alpha-Hydroxyprogesterone; Activities of Daily Living; Adolescent; Child; Chromatography, Liquid; Cortisone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Male; Mass Spectrometry; Pregnenolone; Refugees; Steroids; Stress, Psychological; Sweden; Syndrome; Time Factors; Unconscious, Psychology	2012
Fluconazole inhibits human adrenocortical steroidogenesis in vitro. The Journal of endocrinology, 2012, Volume: 215, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cortodoxone; Desoxycorticosterone; Fluconazole; Humans; Hydrocortisone; Ketoconazole; Pregnenolone; Progesterone	2012
Structures of human steroidogenic cytochrome P450 17A1 with substrates. The Journal of biological chemistry, 2014, Nov-21, Volume: 289, Issue:47 Topics: 17-alpha-Hydroxyprogesterone; Androstenes; Androstenols; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Dehydroepiandrosterone; Estrogens; Heme; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Structure; Mutation; Oxidation-Reduction; Pregnenolone; Progesterone; Protein Binding; Protein Structure, Secondary; Steroid 17-alpha-Hydroxylase; Steroids; Substrate Specificity; Testosterone	2014
Reduced steroidogenesis in patients with PCDH19-female limited epilepsy. Epilepsia, 2017, Volume: 58, Issue:6 Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Cadherins; Case-Control Studies; Child; Child, Preschool; DNA Mutational Analysis; Epilepsy; Estradiol; Female; Genetic Diseases, X-Linked; Gonadal Steroid Hormones; Humans; Hydrocortisone; Intellectual Disability; Pregnanolone; Pregnenolone; Progesterone; Prospective Studies; Protocadherins; Puberty, Precocious; Reference Values	2017
Placental production of progestins is fully effective in villous cytotrophoblasts and increases with the syncytiotrophoblast formation. Molecular and cellular endocrinology, 2020, 01-01, Volume: 499 Topics: 17-alpha-Hydroxyprogesterone; Cell Differentiation; Cell Proliferation; Cells, Cultured; Colforsin; Female; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Humans; Multienzyme Complexes; Placenta; Pregnancy; Pregnenolone; Progesterone; Progesterone Reductase; Progestins; Steroid Isomerases; TNF Receptor-Associated Factor 4; Trophoblasts	2020
A cross-sectional survey of adrenal steroid hormones among overweight/obese boys according to puberty stage. BMC pediatrics, 2019, 11-06, Volume: 19, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Age Factors; Androstenedione; Child; Corticosterone; Cross-Sectional Studies; Dehydroepiandrosterone; Humans; Male; Organ Size; Overweight; Pediatric Obesity; Pregnenolone; Puberty; Puberty, Precocious; Sex Hormone-Binding Globulin; Testis; Testosterone	2019
COVID-19 patients with altered steroid hormone levels are more likely to have higher disease severity. Endocrine, 2022, Volume: 78, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldosterone; Androstenedione; Androsterone; Chromatography, Liquid; Corticosterone; Cortodoxone; COVID-19; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Estradiol; Estrone; Humans; Hydrocortisone; Pregnenolone; Progesterone; Severity of Illness Index; Tandem Mass Spectrometry	2022
Follicle isolation methods reveal plasticity of granulosa cell steroidogenic capacity during mouse in vitro follicle growth. Molecular human reproduction, 2022, 09-29, Volume: 28, Issue:10 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alginates; Alkaline Phosphatase; Androgens; Androstenedione; Animals; Carrier Proteins; Dehydroepiandrosterone; Estradiol; Female; Granulosa Cells; Humans; Inhibins; Lyases; Mice; Pregnenolone; Progesterone; Theca Cells	2022
Steroid Profiling in the Amniotic Fluid: Reference Range for 12 Steroids and Interest in 21-Hydroxylase Deficiency. The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5 Topics: 17-alpha-Hydroxyprogesterone; Amniotic Fluid; Chromatography, Liquid; Corticosterone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Pregnancy; Pregnenolone; Reference Values; Steroids; Tandem Mass Spectrometry; Testosterone	2023