17-alpha-hydroxyprogesterone and androsterone

17-alpha-hydroxyprogesterone has been researched along with androsterone in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (10.71)	18.7374
1990's	8 (28.57)	18.2507
2000's	10 (35.71)	29.6817
2010's	6 (21.43)	24.3611
2020's	1 (3.57)	2.80

Authors

Authors	Studies
Chapman, D; Jain, AN; Koile, K	1
Good, AC; Richards, WG; So, SS	1
Platt, DE; Silverman, BD	1
Crippen, GM	1
Karplus, M; So, SS	1
Hamprecht, FA; Kubinyi, H; Mietzner, T	1
Strassburg, CP; Tukey, RH	1
Clementi, S; Cruciani, G; McLay, I; Pastor, M; Pickett, S	1
Baumann, K; Stiefl, N	1
Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H	1
Higashiura, K; Kotani, T	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Bellavance, E; Luu-The, V; Poirier, D	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Brkljacić, L; Dumić, M; Kastelan, A; Lukenda, M; Mardesić, D; Plavsić, V	1
Goldring, NB; Orly, J	1
Hammond, GL; Hirvonen, J; Vihko, R	1
Rittmaster, RS; Zwicker, H	1
Angeletti, G; Baiocchi, G; Celleno, R; Fratini, D; Gilardi, G; Manci, N	1
Bouchard, C; Gagnon, J; Leon, AS; Rankinen, T; Rao, DC; Skinner, JS; Ukkola, O; Wilmore, JH	1
Fukami, M; Hasegawa, T; Homma, K; Ikeda, K; Koyama, Y; Miwa, M; Murata, M; Ogata, T	1
Asenjo, S; Cassorla, F; Codner, E; Eyzaguirre, FC; Iñíguez, G; López, P; Mujica, V; Torrealba, I	1
Auchus, RJ; Buschur, EO; Chang, AY; Gonzalez, M; Hammer, GD; Jiao, J; Madrigal, D; Ramm, C; Smit, JW; Wang, G; Xu, XS; Yu, MK	1
Backlund, PS; Crutchfield, CA; Debono, M; Gounden, V; Harrison, RF; Mallappa, A; Merke, DP; Nella, AA; Ross, RJ; Soldin, SJ	1
Dao-Tran, A; Davidowitz, E; Geffner, ME; Gilsanz, V; Kim, MS; Nguyen, E; Ryabets-Lienhard, A; Tseng, T	1
Akıncı, E; Bal, C; Erel, Ö; Eser, F; Güner, R; Hasanoglu, İ; Kalem, AK; Kayaaslan, B; Sezer, S; Yılmaz, G	1

Reviews

1 review(s) available for 17-alpha-hydroxyprogesterone and androsterone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000

Trials

2 trial(s) available for 17-alpha-hydroxyprogesterone and androsterone

Article	Year
Metformin for the treatment of hyperandrogenism in adolescents with type 1 diabetes mellitus. Hormone research in paediatrics, 2013, Volume: 80, Issue:5 Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androsterone; Diabetes Complications; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Gonadotropins; Humans; Hyperandrogenism; Hypoglycemic Agents; Metformin; Ovulation	2013
Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency. The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:8 Topics: 17-alpha-Hydroxyprogesterone; Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Adult; Androgen Antagonists; Androgens; Androstadienes; Androstenedione; Androsterone; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Treatment Outcome	2014

Article

Year

Metformin for the treatment of hyperandrogenism in adolescents with type 1 diabetes mellitus.

Hormone research in paediatrics, 2013, Volume: 80, Issue:5

Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androsterone; Diabetes Complications; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Gonadotropins; Humans; Hyperandrogenism; Hypoglycemic Agents; Metformin; Ovulation

2013

Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.

The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:8

Topics: 17-alpha-Hydroxyprogesterone; Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Adult; Androgen Antagonists; Androgens; Androstadienes; Androstenedione; Androsterone; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Treatment Outcome

2014

Other Studies

25 other study(ies) available for 17-alpha-hydroxyprogesterone and androsterone

Article	Year
Compass: predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark. Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15 Topics: Algorithms; Models, Molecular; Models, Statistical; Molecular Conformation; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Surface Properties; Transcortin	1994
Structure-activity relationships from molecular similarity matrices. Journal of medicinal chemistry, 1993, Feb-19, Volume: 36, Issue:4 Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin	1993
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11 Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone	1996
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data. Journal of medicinal chemistry, 1997, Sep-26, Volume: 40, Issue:20 Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin	1997
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 1. Method and validations. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Algorithms; Models, Chemical; Molecular Structure; Neural Networks, Computer; Protein Binding; Static Electricity; Steroids; Structure-Activity Relationship; Transcortin	1997
Three-dimensional quantitative similarity-activity relationships (3D QSiAR) from SEAL similarity matrices. Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14 Topics: Drug Design; Least-Squares Analysis; Molecular Conformation; Steroids; Structure-Activity Relationship; Transcortin	1998
GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors. Journal of medicinal chemistry, 2000, Aug-24, Volume: 43, Issue:17 Topics: Butyrophenones; Enzyme Inhibitors; Glucose; Models, Molecular; Phosphorylases; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Software; Steroids; Transcortin	2000
Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique. Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8 Topics: Acetates; Alcohols; Algorithms; Cholinergic Agents; Hydrocarbons, Acyclic; Hydrocarbons, Aromatic; Ketones; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Receptor, Muscarinic M2; Receptors, Muscarinic; Steroids; Transcortin	2003
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22 Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts	2003
Comparative molecular active site analysis (CoMASA). 1. An approach to rapid evaluation of 3D QSAR. Journal of medicinal chemistry, 2004, May-20, Volume: 47, Issue:11 Topics: Binding Sites; Cluster Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Steroids	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids	2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23 Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity	2009
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
'Cryptic' form of congenital adrenal hyperplasia due to 21-hydroxylase deficiency in the Yugoslav population. Acta endocrinologica, 1985, Volume: 109, Issue:3 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androsterone; Dehydroepiandrosterone; Female; Heterozygote; HLA Antigens; Homozygote; Humans; Hydroxyprogesterones; Male; Pedigree; Steroid Hydroxylases; Yugoslavia	1985
Concerted metabolism of steroid hormones produced by cocultured ovarian cell types. The Journal of biological chemistry, 1985, Jan-25, Volume: 260, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androsterone; Animals; Cells, Cultured; Female; Follicle Stimulating Hormone; Hydroxyprogesterones; Luteinizing Hormone; Ovary; Pregnanediol; Pregnanetriol; Pregnenolone; Progestins; Rats; Rats, Inbred Strains	1985
Progesterone, androstenedione, testosterone, 5 alpha-dihydrotestosterone and androsterone concentrations in specific regions of the human brain. Journal of steroid biochemistry, 1983, Volume: 18, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Adult; Amygdala; Androstenedione; Androsterone; Brain Chemistry; Child, Preschool; Dihydrotestosterone; Female; Humans; Hydroxyprogesterones; Hypothalamus; Male; Middle Aged; Parietal Lobe; Pineal Gland; Pituitary Gland, Anterior; Progesterone; Sex Factors; Testosterone	1983
Androsterone sulfate: physiology and clinical significance in hirsute women. The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:1 Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Androstenedione; Androsterone; Biomarkers; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Follicle Stimulating Hormone; Glucuronates; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Leuprolide; Luteinizing Hormone; Obesity; Reference Values; Testosterone	1993
Pure Leydig cell tumour (hilus cell) of the ovary: a rare cause of virilization after menopause. Gynecologic and obstetric investigation, 1997, Volume: 44, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Androgens; Androstenedione; Androsterone; Circadian Rhythm; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Leydig Cell Tumor; Middle Aged; Ovarian Neoplasms; Postmenopause; Testosterone; Time Factors; Virilism	1997
A genome-wide linkage scan for steroids and SHBG levels in black and white families: the HERITAGE Family Study. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:8 Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Aged; Androsterone; Black People; Cohort Studies; Dihydrotestosterone; Female; Genetic Linkage; Genome, Human; Hormones; Humans; Hydrocortisone; Male; Middle Aged; Pregnenolone; Progesterone; Sex Hormone-Binding Globulin; Testosterone; White People	2002
Two-step biochemical differential diagnosis of classic 21-hydroxylase deficiency and cytochrome P450 oxidoreductase deficiency in Japanese infants by GC-MS measurement of urinary pregnanetriolone/ tetrahydroxycortisone ratio and 11β-hydroxyandrosterone. Clinical chemistry, 2012, Volume: 58, Issue:4 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androsterone; Biomarkers; Case-Control Studies; Diagnosis, Differential; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Male; NADPH-Ferrihemoprotein Reductase; Pregnanetriol; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Tetrahydrocortisone	2012
Hormonal circadian rhythms in patients with congenital adrenal hyperplasia: identifying optimal monitoring times and novel disease biomarkers. European journal of endocrinology, 2015, Volume: 173, Issue:6 Topics: 17-alpha-Hydroxyprogesterone; 5-alpha-Dihydroprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Androsterone; Biomarkers; Circadian Rhythm; Cross-Sectional Studies; Dehydroepiandrosterone; Dexamethasone; Female; Glucocorticoids; Hormones; Humans; Male; Prednisone; Pregnanediones; Progesterone; Testosterone; Young Adult	2015
Carotid Intima-Media Thickness Is Associated with Increased Androgens in Adolescents and Young Adults with Classical Congenital Adrenal Hyperplasia. Hormone research in paediatrics, 2016, Volume: 85, Issue:4 Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Androsterone; Carotid Intima-Media Thickness; Cholesterol, HDL; Female; Humans; Male; Obesity; Sex Characteristics; Young Adult	2016
COVID-19 patients with altered steroid hormone levels are more likely to have higher disease severity. Endocrine, 2022, Volume: 78, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldosterone; Androstenedione; Androsterone; Chromatography, Liquid; Corticosterone; Cortodoxone; COVID-19; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Estradiol; Estrone; Humans; Hydrocortisone; Pregnenolone; Progesterone; Severity of Illness Index; Tandem Mass Spectrometry	2022