17-alpha-hydroxypregnenolone has been researched along with dehydroepiandrosterone in 292 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 212 (72.60) | 18.7374 |
| 1990's | 44 (15.07) | 18.2507 |
| 2000's | 22 (7.53) | 29.6817 |
| 2010's | 12 (4.11) | 24.3611 |
| 2020's | 2 (0.68) | 2.80 |
| Authors | Studies |
|---|---|
| Good, AC; Peterson, SJ; Richards, WG | 1 |
| Good, AC; Richards, WG; So, SS | 1 |
| Platt, DE; Silverman, BD | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Bedrak, E; Chap, Z | 1 |
| Arai, K; Okinaga, S; Sano, Y; Shibusawa, H; Yoshida, N | 1 |
| Bertamino, R; Crovato, F; Moretti, G | 1 |
| John, BM; Pierrepoint, CG | 1 |
| Ifuku, M; Maeyama, M; Nakahara, K | 1 |
| Bell, JB | 1 |
| Abraham, GE; Chang, RJ | 1 |
| Friedrich, E; Schindler, AE | 1 |
| Schindler, AE; Sparke, H | 2 |
| Couch, RA; Doouss, TW; Skinner, SJ | 1 |
| Schindler, AE; Wuchter, J | 1 |
| Leathem, JH; Murono, EP | 1 |
| Mori, T | 2 |
| Abraham, GE; Chakmakjian, ZH | 2 |
| Benagiano, G; de la Torre, B; Diczfalusy, E | 1 |
| Brinkley, HJ; Weiss, JR; Young, EP | 1 |
| Aso, T; Cekan, Z; Diczfalusy, E; Goncharov, N; Pachalia, N | 1 |
| Aso, T; Cekan, Z; Diczfalusy, E; Goncharov, N | 1 |
| Belvedere, PC; Colombo, L | 1 |
| Aedo, AR; Cekan, SZ; Diczfalusy, E; Landgren, BM; Nuñez, M | 1 |
| Genest, J; Guthrie, GP; Kuchel, O; Messeril, FH; Nowaczynski, W | 1 |
| Eastman, AR; Neville, AM | 1 |
| Diczfalusy, E | 1 |
| de la Torre, B; Diczfalusy, E; Hedman, M | 1 |
| Alfieri, L; Benassi, L; Salvadori, B | 1 |
| Preslock, JP; Steinberger, E | 3 |
| Den, M; Haruyama, N; Takasaki, T; Uesato, T; Yoshida, T | 1 |
| Fern, EB; Fern, M; Rose, DP | 1 |
| Bonaventura, LM; Cleary, RE; Judd, H; Roth, LM | 1 |
| Solomon, S; Stanczyk, FZ; Stern, M | 1 |
| Abraham, GE; Bossen, EH; Soules, MR | 1 |
| Edwards, RG; Fowler, RE; Fox, NL; Steptoe, PC | 1 |
| Benveniste, R; Lacroix, A; McKenna, TJ; McNeil, LW; Rabin, D | 1 |
| Bator, JM; Baukal, AJ; Catt, KJ; Cigorraga, SB; Dufau, ML; Neubauer, JF; Sorrell, SH | 1 |
| Benassi, L; Cacciatore, A; Pini, L; Salvadori, B | 1 |
| Den, K; Fujii, KT; Hagiwara, H; Haruyama, T; Kambegawa, A; Takagi, S; Takami, T; Yoshida, T | 1 |
| Shimizu, K | 1 |
| Abul-Hajj, YJ; Iverson, R; Kiang, DT | 1 |
| Samojlik, E; Santen, RJ | 1 |
| Anderson, DC; Yen, SS | 1 |
| Davajan, V; Goebelsmann, U; Israel, R; Mestman, JH; Mishell, DR; Zachmann, M | 1 |
| Genest, J; Kuchel, O; Nowaczynksi, W; Richardson, K | 1 |
| Abraham, GE; Granoff, AB | 1 |
| Abraham, GE; Meldrum, DR | 1 |
| de la Torre, B; Diczfalusy, E; Hedman, M; Norén, S | 1 |
| Andrada, JA; Hoscholan, JC | 1 |
| Nishi, Y; Tezuka, T | 1 |
| Finegold, DN; Lee, PA; McVie, R; Siegel, SF; Urban, MD | 1 |
| Dunaif, A; Futterweit, W; Green, G; Tarlin, N | 1 |
| Borrelli, P; Cambiaso, P; Cappa, M; Danielli, E; del Balzo, P | 1 |
| Akwa, Y; Baulieu, EE; Morfin, RF; Robel, P | 1 |
| Berg, G; Di Martino-Nardi, J; Fishman, K; Gautier, T; Lashansky, G; Mayes, D; Reiter, E; Saenger, P | 1 |
| Fort, P; Jabbar, M; Lifshitz, F; Pugliese, M; Recker, B | 1 |
| Arlotto, MP; Barnes, HJ; Waterman, MR | 1 |
| Engelhardt, D; Luppa, P; Munker, R; Nagel, D; Weber, M | 1 |
| Cooke, GM | 1 |
| Azziz, R; Boots, LR; Bradley, E; Gay, FL; Potter, SR | 1 |
| Grunwald, K; Rabe, T; Runnebaum, B; Urbancsek, J; Vecsei, P | 1 |
| Lorence, MC; Mason, JI; Murry, BA; Trant, JM | 1 |
| Hirato, K; Yanaihara, T | 1 |
| Nishi, Y | 1 |
| Finegold, DN; Lanes, R; Lee, PA; Siegel, SF | 1 |
| Frank-Raue, K; Korth-Schütz, S; Raue, F; Vecsei, P; Ziegler, R | 1 |
| Imataka, H; Inano, H; Kohmoto, K; Suzuki, K; Tamaoki, B | 1 |
| Job, JC; Leymarie, P; Nahoul, K; Perrin, C | 1 |
| Berg, GJ; Lee, MM; Moshang, T; Rajagopalan, L | 1 |
| Hurwitz, A; Laufer, N; Palti, Z; Rösler, A; Schenker, JB; Vecsei, P | 1 |
| Adams, J; Hague, WM; Honour, JW; Jacobs, HS; Vecsei, P | 1 |
| Lobo, RA; Rosen, GF; Silva, PD; Vermesh, M; Vijod, AG | 1 |
| McCarthy, JL; Waterman, MR | 1 |
| De Clerck, D; De Loof, A; Diederik, H; Ollevier, F | 1 |
| Deslypere, JP; Vermeulen, A | 1 |
| Hashino, M; Maruyama, S; Matsumura, I; Nakayama, T; Yanaihara, T | 1 |
| Singh, S; Singh, TP | 1 |
| Crabbe, J; Kolanowski, J; Ortega, N | 1 |
| Gunasegaram, R; Kottegoda, SR; Loganath, A; Peh, KL; Ratnam, SS; Thiagaraj, D | 1 |
| Maki, T | 1 |
| Goshima, E; Hirai, M; Miura, K; Murase, H; Murayama, M; Noritake, N; Takeda, N; Yamakita, N; Yasuda, K | 1 |
| Byrne, GC; Perry, YS; Winter, JS | 1 |
| Narita, O; Okuyama, S; Takagi, K; Tomoda, Y; Wu, MC | 1 |
| Gower, DB; Kwan, TK; Taylor, NF; Watson, D | 1 |
| Hofman, LF; Klaniecki, JE; Smith, EK | 1 |
| Alén, M; Bolton, N; Ruokonen, A; Vihko, R | 1 |
| Bongiovanni, AM; Cara, JF; Marx, BS; Moshang, T | 1 |
| Kannari, K; Kimura, K; Takebe, K; Watanobe, H | 1 |
| Fan, DF; Nankin, HR; Oshima, H; Pan, SF; Talbott, JB; Troen, P | 1 |
| Bedrak, E; Samoiloff, V; Sod-Moriah, UA | 1 |
| Oh, R; Tamaoki, B | 1 |
| Deshpande, N; Yates, J | 1 |
| Katukawa, H; Nakamura, T; Tanabe, Y | 1 |
| Aakvaag, A; Eik-Nes, KB | 1 |
| Burgett, MJ; Slaunwhite, WR | 1 |
| Oertel, GW; Rindt, W; Weinand, K | 1 |
| Vihko, R | 1 |
| Kahnt, FW; Neher, R | 1 |
| Grant, JK; Griffiths, K; Pierrepoint, CG; Stewart, JS | 1 |
| Reynolds, JW | 1 |
| Bandi, L; Calvin, HI; Cos, JJ; Lieberman, S; Roberts, KD; Weiss, C | 1 |
| Schuetz, AW | 1 |
| Brownie, AC; Hoschoian, JC | 2 |
| Diczfalusy, E; Jaffee, RB; Pion, RJ; Wiqvist, N | 1 |
| Jaffe, RB; Pérez, AE; Perez-Palacios, G | 1 |
| Christie, GA | 1 |
| Wolff, HP | 1 |
| Ebersohl, C; Oertel, GW; Rindt, W | 1 |
| Chieffi, G; Delrio, G; Di Prisco, CL | 1 |
| Schindler, AE; Siiteri, PK | 1 |
| Leymarie, P; Savard, K | 1 |
| Givner, ML; Jaffe, RB; Lamont, KG; Pérez-Palacios, G | 1 |
| Cooke, BA | 1 |
| Anderson, JM; McCormick, MH; Neville, AM; Webb, JL | 1 |
| Garcia, O; Green, OC; Hamwi, GJ; Miller, RR | 1 |
| Lisse, K; Schürenkämper, P | 1 |
| Desplanques, D; Grangaud, R; Nicol, M | 1 |
| Anderson, AB; Cameron, EH; Griffiths, K; Jones, D; Jones, T | 1 |
| Tan, L | 1 |
| Bulbrook, RD; Carson, P; Deshpande, N; Doouss, TW; Jensen, V | 1 |
| Huhtaniemi, I; Luukkainen, T; Vihko, R | 1 |
| Eik-Nes, KB; Frankel, AI | 1 |
| Cooke, BA; Cowan, RA; Taylor, PD | 1 |
| Dorfman, RI; Gottfried, H | 1 |
| Jaffe, RB; Lamont, KG; Pérez, AE; Pérez-Palacios, G | 1 |
| Bermudez, JA; Lipsett, MB; Strott, CA | 1 |
| Burn, JI; Deshpande, N; Doouss, TW | 1 |
| Bloch, E; Klein, M; Lew, M | 1 |
| Francis, FE; Kinsella, RA | 1 |
| Carson, P; Deshpande, N; Harley, S | 1 |
| Lanthier, A; Patwardhan, VV | 1 |
| Bicknell, DC; Gower, DB | 1 |
| Cooke, BA; Dobbie, J; Shirley, IM; Taylor, PD | 1 |
| Cooke, BA; Taylor, PD | 1 |
| Braunberger, G; Menzel, P; Oertel, GW; Rindt, W | 1 |
| Troen, P; Yanaihara, T | 1 |
| Furuyama, J; Matsumoto, K; Mizutani, S; Sonoda, T; Takemura, M | 1 |
| Laatikainen, T; Laitinen, EA; Ruokonen, A; Vihko, R | 1 |
| De Kretser, DM; Lording, DW | 1 |
| Falardeau, P; Tan, L; Wang, HM | 1 |
| Trout, EC | 1 |
| Affanni, JM; Galli, FE; Irusta, O; Wassermann, GF | 1 |
| Dizzfalusy, E; Jaffe, RB; Pérez-Palacios, G | 1 |
| Huhtaniemi, I; Vihko, R | 1 |
| Nakamura, T; Tanabe, Y | 2 |
| Axelrod, LR; Milewich, L | 1 |
| Gupta, C; Karavolas, HJ | 1 |
| de Bruijn, HW; van der Molen, HJ | 1 |
| Tingari, MD | 1 |
| Basile, C; Cardellini, LB; Lupo Di Prisco, C; Magni, AP; Rocchi, G | 1 |
| Abraham, GE; Buster, JE; Corrales, PC; Kyle, FW; Teller, RC | 1 |
| Kent, J | 1 |
| Davies, IJ; Ryan, KJ | 1 |
| Dyková, H; Stárka, L; Sulcová, J | 1 |
| Huhtaniemi, I | 2 |
| de Longcamp, D; Drosdowsky, M; Lubet, P | 1 |
| Lofts, B; Phillips, JG; Tam, WH; Tsui, HW | 1 |
| Hipkin, LJ | 1 |
| Eechaute, W; Lacroix, E; Leusen, I | 1 |
| Laatikainen, TJ; Nylander, PL; Peltonen, JI | 1 |
| Nice, E; Williams, K | 1 |
| Lipsett, MB; Loriaux, DL; Ruder, HJ | 1 |
| Brophy, PJ; Gower, DB | 1 |
| Jaffe, RB; Payne, AH | 1 |
| Mackay, AM; Neville, AM; Pettigrew, N; Symington, T | 1 |
| Juillard, MT; Malassiné, A | 1 |
| Kadis, B | 1 |
| Briefer, C; Federman, DD; Kliman, B; Rotner, H; Villee, DB | 1 |
| Camacho, AM; Hagen, AA; Trouy, RL; Wilroy, RS | 1 |
| Lauritzen, C; Mitchell, FL; Shackleton, CH | 1 |
| Berger, GM | 1 |
| Eik-Nes, KB; van der Molen, HJ | 1 |
| Gregorová, I; Horký, K; Kuchel, O; Stárka, L | 1 |
| Iglesias, R; Irusta, O; Van Houtte, I; Wassermann, GF | 1 |
| McKerns, KW; Nordstrand, E | 1 |
| Kao, KY; McGavack, TH; Trout, EC | 1 |
| Bote, V; Chieffi, G; Tramontana, S | 1 |
| Fevold, HR; Pfeiffer, EW | 1 |
| Huseby, RA; Samuels, LT; Uchikawa, T; Zain-ul-Abedin, M | 1 |
| Bedrak, E; Samuels, LT | 1 |
| Carson, P; Deshpande, N; Jensen, V | 2 |
| Cardinali, DP; Cuello, AE; Rosner, JM; Tramezzani, JH | 1 |
| Bedrak, E | 1 |
| Arai, K; Okinaga, S; Sano, Y; Sekiba, K; Shibusawa, H; Yoshida, N | 1 |
| Lucky, AW; Lucky, PA; McGuire, J; Rich, BH; Rosenfield, RL | 1 |
| Homoki, J; Roitman, E; Shackleton, CH | 1 |
| Bolton, NJ; Huhtaniemi, I; Martikainen, H; Vihko, R | 1 |
| Bedrak, E; Friedlander, M; Kafka, M; Rosenstrauch, A | 1 |
| Nishikawa, T; Strott, CA | 1 |
| Lykkesfeldt, AE; Lykkesfeldt, G; Nielsen, MD | 1 |
| Bermúdez, JA; Gómez, S; González Garza, MT; Herrera, J; Montalvo, I; Sotelo, A | 1 |
| Capella-Pavlovsky, M; Castanier, M; Chartier, M; Daffos, F; Forestier, F; Nahoul, K; Scholler, R | 1 |
| Bhatia, K; Mead, RA; Ravindra, R | 1 |
| Gibson, M; Lackritz, R; Schiff, I; Tulchinsky, D | 1 |
| Barbieri, R; Fencl, MD; Schiff, I; Stillman, RJ; Tulchinsky, D | 1 |
| de Peretti, E; Forest, MG; Lecornu, M | 1 |
| Helke, JC; Lucky, AW; Otto, P; Rich, BH; Rosenfield, RL | 1 |
| Faiman, C; Fujieda, K; Reyes, FI; Winter, JS | 1 |
| Goebelsmann, U; Lobo, RA | 1 |
| Aedo, AR; Diczfalusy, E; Landgren, BM | 1 |
| Deslypere, JP; Rubens, R; Schelfhout, W; Verdonck, L; Vermeulen, A | 1 |
| Buster, JE; Elsner, C; Freeman, A; Fridshal, D; Magyar, D; Nathanielsz, PW | 1 |
| Hemsell, PG; Korte, K; Mason, JI | 1 |
| Bongiovanni, AM | 1 |
| Hoffman, DI; Klove, K; Lobo, RA | 1 |
| Kawakura, K; Matsukura, S; Mori, M; Tamaoki, B | 1 |
| Anderson, CE; Cederqvist, LL; Duchon, MA; Fuentes, M; Holcombe, JH; Levine, LS; Merkatz, I; New, MI; Nitowsky, HM; Owens, R; Pang, S; Riccardi, VM; Sachs, G | 1 |
| Barboni, F; Bartolotta, E; Cacciari, E; Cassio, A; Chiumello, G; Dupont, B; Gargantini, L; Giovannelli, G; Kohn, B; Lerner, A; Levine, LS; Lorenzen, F; Mantero, F; Migliori, C; New, MI; Oberfield, S; Pang, S; Pintor, C; Pollack, M; Rondanini, GF; Scaroni, C; Tato, L; Virdis, R | 1 |
| Buster, JE; Eliot, J; Elsner, CW; Glatz, T; Magyar, DM; Nathanielsz, PW | 1 |
| Kojima, S; Nakayama, T; Yanaihara, T | 1 |
| Hall, PF; Nakajin, S | 1 |
| Gothoda, Y; Hirato, K; Kanbegawa, A; Nakayama, T; Yanaihara, T | 1 |
| Bruchis, C; Galatzer, A; Kauli, R; Lazar, L; Nordenberg, J; Pertzelan, A | 2 |
| Berrod, JL; Kuhn, JM; Mahoudeau, J; Reznik, Y; Rieu, M; Vannetzel, JM | 1 |
| Araneo, BA; Barton, S; Daynes, RA; Ryu, SY | 1 |
| Kominami, S; Nishida, N; Takemori, S; Yamazaki, T | 1 |
| Blades, B; Cowell, CT; Donaghue, K; Howard, NJ; Kreutzmann, DJ; Likitmaskul, S; Silink, M | 1 |
| Kagawa, N; Katagiri, M; Waterman, MR | 1 |
| Aubin, P; Belanger, A; Boudou, P; Brérault, JL; Fiet, J; Galons, H; Gosling, JP; Julien, R; Soliman, H; Villette, JM | 1 |
| Balducci, R; Boscherini, B; Mangiantini, A; Morellini, M; Toscano, V | 1 |
| Alvarez, S; Arteaga, E; Campino, C; Cattani, A; González, G; López, JM; Rodriguez, JA; Rojas, A; Sapunar, J | 1 |
| Acosta, CK; Kim, HK; Rao, PN | 1 |
| Barnes, RB; Brigell, DF; Ehrmann, DA; Rosenfield, RL | 1 |
| Azziz, R; Boots, LR; Bradley, EL; Potter, HD | 1 |
| Bernasconi, S; Cappa, M; Ghizzoni, L; Ibañez, L; Street, ME; Virdis, R; Vottero, A; Zampolli, M | 1 |
| Balducci, R; Brun, E; Castello, R; Moghetti, P; Muggeo, M; Negri, C; Spiazzi, GG; Toscano, V; Tosi, F | 1 |
| Chang, YT; Jorgensen, V; Kappy, M; Pang, S; Sakkal-Alkaddour, H; Slover, RS; Yang, X; Zhang, L | 1 |
| Carrascosa, A; Ibáñez, L; Potau, N; Street, ME; Zampolli, M | 1 |
| Best, R; Björkhem, I; Dott, K; Kieny, MP; Lathe, R; Rose, KA; Russell, DW; Schwarz, M; Seckl, J; Stapleton, G | 1 |
| Kobayashi, Y; Kusuda, S; Tagawa, N | 1 |
| Audí Parera, L; Foz Sala, M; Granada Ybern, ML; Lucas Martín, A; Pizarro Lozano, E; Salinas Vert, I; Sanmartí Sala, A | 1 |
| Balducci, R; Boscherini, B; Di Rito, A; Galasso, C; Larizza, D; Mangiantini, A; Municchi, G; Picone, S; Toscano, V | 1 |
| Bosc, MJ; Nicolle, A | 1 |
| Beaudoin, C; Bélanger, A; Breton, R; de Launoit, Y; Hum, DW; Lavallée, B; Tremblay, Y | 1 |
| Funahashi, H; Imai, T; Kikumori, T; Morita-Matsuyama, T; Sasano, H; Seo, H; Tobinaga, J | 1 |
| Altare, S; Canivet, B; Hadjali, Y; Kézachian, B; Sadoul, JL | 1 |
| Luu-The, V; Soucy, P | 1 |
| Azziz, R; Boots, LR; Decanter, C; Dewailly, D; Huerta, R; Knochenhauer, ES | 1 |
| Barnes, RB; Layman, LC; Namnoum, A; Rosenfield, RL | 1 |
| Beaujean, D; Do-Rego, JL; Leprince, J; Luu-The, V; Mensah-Nyagan, AG; Pelletier, G; Tonon, MC; Vaudry, H | 1 |
| Bersi, C; Fruzzetti, F; Genazzani, AD; Genazzani, AR; Luisi, M; Luisi, S; Malavasi, B; Petraglia, F | 1 |
| Belvedere, P; Carnevali, O; Colombo, L; Dalla Valle, L; Vianello, S | 1 |
| Bicíková, M; Hill, M; Stárka, L; Tallová, J; Vrbíková, J | 1 |
| Kobayashi, Y; Nakamura, N; Nakano, K; Obayashi, H; Ohta, M; Tagawa, N | 1 |
| Dorner, M; Falk, W; Schölmerich, J; Straub, RH; Vogl, D | 1 |
| CARTER, AC; LIEBERMAN, S; SOLOMON, S | 1 |
| CLARK, AF; SOLOMON, S | 1 |
| CALVIN, HI; LIEBERMAN, S | 1 |
| DORFMAN, RI; SHARMA, DC | 1 |
| KILLINGER, DW; SOLOMON, S | 1 |
| LORING, JM; VILLEE, CA | 1 |
| CRAWFORD, JD; KLIMAN, B; MACGILLIVRAY, M; SCULLY, RE; VILLEE, DB | 1 |
| BOMPIANI, A; KAHNT, FW; NEHER, R; ROVERSI, GD | 1 |
| BRUEHL, P; KAISER, E; OERTEL, GW; ZIMMERMANN, W | 1 |
| SCHEDEWIE, H; TAMM, J; VOIGT, KD; VOLKWEIN, U | 1 |
| Azziz, R; Bartolucci, AA; Farah-Eways, L; Knochenhauer, ES; Reyna, R | 1 |
| Bair, SR; Mellon, SH | 1 |
| Bicíková, M; Hampl, R; Havlíková, H; Hill, M; Jirák, R; Rípová, D; Tallová, J | 1 |
| de Castro, M; Elias, LL; Marui, S; Mendonca, BB; Mermejo, LM; Moreira, AC | 1 |
| Boretti, FS; Maser-Gluth, C; Reusch, CE; Sieber-Ruckstuhl, NS; Wenger, M | 1 |
| Havlíková, H; Hill, M; Kancheva, L; Sobotka, V; Stárka, L | 1 |
| Katagiri, M; Kobayashi, Y; Tagawa, N | 1 |
| Boudou, P; Calvo, F; Gautier, JF; Ibrahim, F; Porcher, R; Sobngwi, E; Vexiau, P | 1 |
| Leprince, J; Luu-The, V; Pelletier, G; Rego, JL; Tonon, MC; Vaudry, H | 1 |
| Billen, MJ; Squires, EJ | 1 |
| Goosen, P; Storbeck, KH; Swart, AC; Swart, P | 1 |
| Akashi, T; Hiraishi, K; Hirata, Y; Homma, K; Izumiyama, H; Kihara, K; Kouyama, R; Shibata, H; Sugiyama, T; Yoshimoto, T | 1 |
| Arslanian, SA; Hannon, TS | 1 |
| Hartmann, MF; Kamrath, C; Wudy, S | 1 |
| Gregory, M; Kincaid, JR; Mak, PJ; Sligar, SG | 1 |
| Blanche, S; Frange, P; Kariyawasam, D; Laborde, K; Parat, S; Polak, M; Simon, A; Souchon, PF | 1 |
| do Rego, JL; Vaudry, D; Vaudry, H | 1 |
| Denisov, IG; Gregory, MC; Kincaid, JR; Mak, PJ; Sligar, SG | 1 |
| Chaube, R; Mishra, S | 1 |
| Abdelwahab, A; Ahmed, A; Ahmed, H; Hallman, M; Khashana, A; Rämet, M; Saarela, T | 1 |
| Gregory, MC; Khatri, Y; Kincaid, JR; Mak, PJ; Sligar, SG | 1 |
| Hartmann, MF; Sánchez-Guijo, A; Tiosano, D; Wang, R; Wudy, SA | 1 |
| Eriksen, GS; Johannsen, ML; Mallia, V; Ropstad, E; Styrishave, B; Uhlig, S; Verhaegen, S | 1 |
| Babayev, E; Duncan, FE; Shea, LD; Woodruff, TK; Xu, M | 1 |
4 review(s) available for 17-alpha-hydroxypregnenolone and dehydroepiandrosterone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Studies on steroids in urine of the male newborn.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Arylsulfatases; Dehydroepiandrosterone; Glucuronidase; Humans; Hydrolysis; Hydroxyprogesterones; Infant, Newborn; Male; Pregnanediol; Pregnanes; Pregnanolone; Pregnenolone; Progesterone | 1975 |
[Clinical steroid analysis, using H3 and C14 (determination of their secretion, plasma concentration, secretion rate, as well as metabolism and renal clearance rate)].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Aldosterone; Carbon Isotopes; Chemistry, Clinical; Dehydroepiandrosterone; Heart Failure; Humans; Hydrocortisone; Hypertension, Renal; Kidney; Liver Cirrhosis; Nephrotic Syndrome; Radioisotope Dilution Technique; Secretory Rate; Steroids; Tritium | 1965 |
[The alternative androgen synthesis pathway in humans].
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Androgens; Androstenedione; Animals; Child; Child, Preschool; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Infant; Infant, Newborn; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Pregnancy; Prostatic Neoplasms; Sex Differentiation; Steroid 21-Hydroxylase; Testis; Testosterone | 2013 |
2 trial(s) available for 17-alpha-hydroxypregnenolone and dehydroepiandrosterone
| Article | Year |
|---|---|
Effect of aminoglutethimide on urinary steroid excretion in patients with congenital adrenal hyperplasia due to incomplete 21-hydroxylase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Androsterone; Aniline Compounds; Anticonvulsants; Chemistry, Clinical; Clinical Trials as Topic; Dehydroepiandrosterone; Depression, Chemical; Dexamethasone; Etiocholanolone; Female; Humans; Metabolism, Inborn Errors; Metyrapone; Mixed Function Oxygenases; Pregnanetriol; Pyridones | 1972 |
C16 hydroxylation of 3beta-hydroxy-delta5-steroids during the early neonatal period.
Topics: 17-alpha-Hydroxypregnenolone; Calibration; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Hydroxysteroids; Infant, Newborn; Infant, Premature; Male | 1997 |
286 other study(ies) available for 17-alpha-hydroxypregnenolone and dehydroepiandrosterone
| Article | Year |
|---|---|
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship | 1993 |
Structure-activity relationships from molecular similarity matrices.
Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin | 1993 |
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone | 1996 |
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids | 2008 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
In vitro testosterone synthesis by testicular tissue of old mouse: the metabolism of 3beta-hydroxy-5-ene steroids.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Androgens; Androstenediols; Androstenedione; Animals; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Mice; Mice, Inbred C57BL; NADP; Pregnenolone; Progesterone; Testis; Testosterone | 1977 |
Studies of the human fetal adrenal gland--properties of 17alpha-hydroxylase and C17-C20 lyase in the biosynthesis of dehydroepiandrosterone from pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Dehydroepiandrosterone; Female; Fetus; Humans; Hydrogen-Ion Concentration; Lyases; Microsomes; NADP; Oxidoreductases; Pregnancy; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Subcellular Fractions | 1978 |
Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Cytoplasm; Cytoplasmic Granules; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Hair; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Rats; Sebaceous Glands; Skin; Testosterone | 1975 |
Demonstration of an active C17-C20 lyase in the sheep placenta.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gestational Age; Gonadal Steroid Hormones; Hydroxyprogesterones; In Vitro Techniques; Lyases; Placenta; Pregnancy; Sheep; Solvents; Testosterone | 1975 |
Steroidogenesis in cerebral metastatic chorionepithelioma tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Brain Neoplasms; Choriocarcinoma; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Humans; In Vitro Techniques; Neoplasm Metastasis; Pregnancy; Progesterone; Steroids; Testosterone | 1975 |
Studies of in vitro steroid metabolism by testis tissue from 'complete' and 'incomplete' forms of testicular feminization.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androgen-Insensitivity Syndrome; Androstane-3,17-diol; Androstenediols; Androstenedione; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Male; Pregnanolone; Pregnenolone; Progesterone; Testis; Testosterone | 1975 |
Peripheral steroid levels in a patient with congenital absence of the uterus.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Amenorrhea; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Follicular Phase; Humans; Hydrocortisone; Hydroxyprogesterones; Karyotyping; Luteal Phase; Luteinizing Hormone; Pregnanolone; Progesterone; Steroids; Testosterone; Uterus | 1975 |
Steroid metabolism of foetal tissues. I. Metabolism of pregnenolone-4-14C by human foetal ovaries.
Topics: 17-alpha-Hydroxypregnenolone; Age Factors; Androstenedione; Dehydroepiandrosterone; Estradiol; Estrone; Female; Fetus; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Ovarian Cysts; Ovary; Pituitary Gland; Pregnenolone; Progesterone; Testis; Testosterone | 1975 |
Steroids in umbilical cord plasma from normal term deliveries.
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenols; Dehydroepiandrosterone; Estetrol; Estriol; Female; Fetal Blood; Humans; Hydroxyprogesterones; Male; Pregnanediol; Pregnenolone; Progesterone; Steroids | 1975 |
Synthesis of dehydroepiandrosterone and dehydroepiandrosterone sulphate by the human adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Corticosterone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Sulfates | 1975 |
Method for the quantitation of steroids in umbilical cord plasma.
Topics: 17-alpha-Hydroxypregnenolone; Androstenes; Arylsulfatases; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estriol; Fetal Blood; Humans; Hydrolysis; Infant, Newborn; Ketosteroids; Pregnanediol; Pregnenolone; Progesterone; Steroids | 1975 |
Ovarian delta-5-3-beta-hydroxysteroid dehydrogenase in aging rats.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Corpus Luteum; Cricetinae; Dehydroepiandrosterone; Female; Granulosa Cells; Humans; Hydroxysteroid Dehydrogenases; Mice; Ovary; Pregnenolone; Rats; Theca Cells | 1975 |
Steroid hormone formation in bovine ovarian follicles.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androgens; Androstenedione; Animals; Cattle; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Ovary; Progesterone; Testosterone | 1975 |
Peripheral steroid levels in a patient with virilizing adrenal adenoma.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adult; Androstenedione; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids; Testosterone; Virilism | 1975 |
Pathways of testosterone synthesis in decapsulated testes of mice.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Hydroxyprogesterones; Lanosterol; Leydig Cells; Male; Mice; Pregnenolone; Progesterone; Squalene; Stimulation, Chemical; Testis; Testosterone | 1976 |
In vitro steroidogenesis in porcine corpora lutea.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Corpus Luteum; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Progestins; Swine; Testosterone | 1976 |
Hormonal changes during the menstrual cycle of the baboon (Papio hamadryas).
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Adrenal Cortex Hormones; Androgens; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogens; Estrone; Female; Haplorhini; Humans; Hydroxyprogesterones; Menstruation; Papio; Pregnenolone; Progesterone; Progestins; Species Specificity; Testosterone | 1976 |
Plasma levels of unconjugated steroids in male baboons (Papio hamadryas) and rhesus monkeys (Macaca mulatta).
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Gonadal Steroid Hormones; Haplorhini; Humans; Hydroxyprogesterones; Macaca; Macaca mulatta; Male; Middle Aged; Papio; Pregnenolone; Radioimmunoassay; Species Specificity; Testosterone | 1976 |
Steroid biosynthesis by the ovary of the European eel, Anguilla anguilla L., at the silver stage.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androstenedione; Androsterone; Animals; Dehydroepiandrosterone; Eels; Female; Hydroxyprogesterones; Kinetics; Metyrapone; Ovary; Pregnenes; Pregnenolone; Progesterone; Testosterone | 1976 |
Steroid hormone formation in human ovarian follicles in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Ovary; Pregnenolone; Progesterone; Progestins; Testosterone | 1976 |
Studies on the pattern of circulating steroids in the normal menstrual cycle. Circadian variation in theperi-ovulatory period.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Circadian Rhythm; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Menstruation; Pregnenolone; Reference Values; Testosterone | 1977 |
Origin of urinary 16 beta-hydroxydehydroepiandrosterone in essential hypertension.
Topics: 17-alpha-Hydroxypregnenolone; Dehydroepiandrosterone; Glucuronates; Humans; Hypertension; Renin; Sulfates | 1977 |
5-ene-3beta-hydroxysteroid dehydrogenase of human and bovine adrenocortical endoplasmic reticulum: solubilization and fractionation.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Cattle; Centrifugation, Density Gradient; Chromatography, Gel; Dehydroepiandrosterone; Endoplasmic Reticulum; Humans; Hydroxysteroid Dehydrogenases; Isoelectric Focusing; Molecular Weight; Pregnenolone | 1977 |
Interrelations between plasma levels of biologically active LH and ovarian and adrenal steroids in the normal menstrual cycle.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Circadian Rhythm; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Luteinizing Hormone; Menstruation; Pregnenolone; Progesterone; Radioimmunoassay | 1977 |
Species differences in steroidogenesis following the in vitro incubation of decapsulated testes.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Gonadal Steroid Hormones; Guinea Pigs; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Testis; Testosterone | 1977 |
[C(16)-substituted steroids--amniotic fluid concentration in the course of normal and pathologic pregnancy].
Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androstenediols; Dehydroepiandrosterone; Estriol; Female; Humans; Isomerism; Pregnancy; Pregnancy Complications; Prognosis; Steroids | 1977 |
Substrate specificity for androgen biosynthesis in the primate testis.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Callitrichinae; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Substrate Specificity; Testis; Testosterone | 1978 |
[Simultaneous determination of pregnenolone, 17 alpha-hydroxypregnenolone and dehydroepiandrosterone].
Topics: 17-alpha-Hydroxypregnenolone; Dehydroepiandrosterone; Female; Humans; Infant, Newborn; Pregnancy; Pregnenolone; Radioimmunoassay | 1978 |
Effect of oral contraceptives on plasma androgenic steroids and their precursors.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androstenedione; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Dehydroepiandrosterone; Female; Humans; Pregnenolone | 1978 |
Androgen, estrogen, and progesterone by a lipid cell tumor of theovary.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovarian Neoplasms; Ovary; Pregnenolone; Progestins; Testosterone; Veins; Virilism | 1978 |
Isolation fo 15alpha-hydroxypregnenolone and 15alpha-hydroxydehydroisoandrosterone from human pregnancy urine.
Topics: 17-alpha-Hydroxypregnenolone; Carbon Radioisotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Humans; Pregnancy; Pregnancy Trimester, Third; Radioisotope Dilution Technique; Tritium | 1978 |
The steroid profile of a virilizing ovarian tumor.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Female; Granulosa Cell Tumor; Hormones; Humans; Hydroxyprogesterones; Leydig Cell Tumor; Neoplasms, Gonadal Tissue; Ovarian Neoplasms; Pregnenolone; Sertoli Cell Tumor; Testosterone; Virilism | 1978 |
Steroid production from 17alpha-hydroxypregnenolone and dehydroepiandrosterone by human granulosa cells in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Cells, Cultured; Dehydroepiandrosterone; Estradiol; Female; Granulosa Cells; Humans; Progesterone | 1978 |
Testicular steroidogenesis in the baboon Papio anubis.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; In Vitro Techniques; Male; Papio; Pregnenolone; Progesterone; Testis; Testosterone | 1978 |
Seventy-two hour infusions of LHRH in normal men: gonadotropin and testicular steroid responses.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Estradiol; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Luteinizing Hormone; Male; Progesterone; Progestins; Testosterone | 1979 |
Steroid biosynthetic lesions in gonadotropin-desensitized Leydig cells.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Hydroxyprogesterones; Leydig Cells; Male; Pregnenolone; Progesterone; Rats; Steroids; Testosterone | 1979 |
[16-substituted steroids in the fetus and newborn in pregnancies complicated by toxemias].
Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androstenediols; Dehydroepiandrosterone; Estriol; Female; Fetus; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy | 1979 |
Plasma levels of 16 alpha-hydroxypregnenolone, 16 alpha-hydroxyprogesterone and 16 alpha-hydroxydehydroepiandrosterone in the fetus and neonates.
Topics: 17-alpha-Hydroxypregnenolone; Dehydroepiandrosterone; Female; Fetal Blood; Humans; Hydroxyprogesterones; Infant, Newborn; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Radioimmunoassay | 1979 |
Metabolism of [17-2H]pregnenolone into 5-[17 beta-2H, 17 alpha-18O]androstene-3 beta, 17 alpha-diol and other products by incubation with the microsomal fraction of boar testis under 18O2 atmosphere.
Topics: 17-alpha-Hydroxypregnenolone; Androstadienes; Androstenediol; Androstenediols; Animals; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Male; Microsomes; Oxygen Isotopes; Pregnenolone; Swine; Testis; Time Factors | 1979 |
Metabolism of pregnenolone and progesterone by testicular microsomes of the baboon Papio anubis and the marmoset Saguinus oedipus.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Callitrichinae; Dehydroepiandrosterone; In Vitro Techniques; Male; Microsomes; Papio; Pregnenolone; Progesterone; Testis; Testosterone | 1979 |
Metabolism of pregnenolone by human breast cancer. Evidence for 17 alpha-hydroxylase and 17,20-lyase.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aldehyde-Lyases; Androstenedione; Breast Neoplasms; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydroxyprogesterones; Menopause; Middle Aged; Pregnenolone; Progesterone; Receptors, Estrogen; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1979 |
Adrenal suppression with aminoglutethimide. III. Comparison of plasma delta 4- and delta 5-steroids in postmenopausal women treated for breast carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; Aminoglutethimide; Androgens; Androstenedione; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydroxyprogesterones; Menopause; Progesterone; Progestins | 1978 |
Effects of estrogens on adrenal 3 beta-hydroxysteroid dehydrogenase in ovariectomized women.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenediols; Androstenedione; Castration; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Pregnenolone; Progesterone; Testosterone | 1976 |
Male pseudohermaphroditism consistent with 17,20-desmolase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hydroxyprogesterones; Luteinizing Hormone; Lyases; Male; Phenotype; Pregnenolone; Progesterone; Testosterone | 1976 |
[Do aldosterone and other mineralocorticoids play a role in the pathogenesis of essential hypertension?].
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Proteins; Circadian Rhythm; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxylation; Hypertension; Liver; Liver Circulation; Metabolic Clearance Rate; Mineralocorticoids; Mixed Function Oxygenases; Posture; Progesterone; Protein Binding | 1977 |
Peripheral and adrenal venous levels of steroids in a patient with virilizing adrenal adenoma.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androstenediols; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Testosterone; Veins | 1979 |
Peripheral and ovarian venous concentrations of various steroid hormones in virilizing ovarian tumors.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Androstanes; Androstenediols; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Middle Aged; Ovarian Neoplasms; Ovary; Progesterone; Sertoli-Leydig Cell Tumor; Testosterone; Veins | 1979 |
Effect of cyproterone acetate (CPA) on gonadal and adrenal function in men.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cyproterone; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Humans; Hydrocortisone; Luteinizing Hormone; Male; Middle Aged; Testis; Testosterone; Time Factors | 1979 |
Androgen biosynthesis in experimental cryptorchidism.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Cryptorchidism; Dehydroepiandrosterone; Guinea Pigs; Hydroxyprogesterones; Male; Pregnenolone; Testis; Testosterone | 1975 |
Mild adrenal 3 beta-hydroxysteroid dehydrogenase deficiency in children with accelerated growth, premature pubarche and/or hirsutism.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenocorticotropic Hormone; Age Determination by Skeleton; Androstenedione; Child; Dehydroepiandrosterone; Dexamethasone; Female; Growth Disorders; Hirsutism; Humans; Hydroxyprogesterones; Male; Sexual Maturation; Testosterone | 1992 |
Premature pubarche: etiological heterogeneity.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Diseases; Adrenocorticotropic Hormone; Androstenedione; Child; Cortodoxone; Dehydroepiandrosterone; Female; Genitalia, Female; Genitalia, Male; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Progesterone; Reference Values | 1992 |
Chronic high-dosage androgen administration to ovulatory women does not alter adrenocortical steroidogenesis.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Injections, Intravenous; Middle Aged; Ovulation; Prospective Studies; Statistics as Topic; Testosterone; Transsexualism | 1992 |
Adrenal steroidogenic defects in children with precocious pubarche.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; Infant; Male; Puberty, Precocious | 1992 |
Neurosteroid metabolism. 7 alpha-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Brain; Dehydroepiandrosterone; Estrogens; Hydroxylation; Kinetics; Male; Microsomes; Mixed Function Oxygenases; Pregnenolone; Rats; Rats, Sprague-Dawley; Substrate Specificity | 1992 |
Normative data for adrenal steroidogenesis in a healthy pediatric population: age- and sex-related changes after adrenocorticotropin stimulation.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Aging; Androstenedione; Child; Child, Preschool; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Infant; Male; Radioimmunoassay; Reference Values; Sex Characteristics; Steroids; Testosterone | 1991 |
Excess weight and precocious pubarche in children: alterations of the adrenocortical hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androstenedione; Body Weight; Child; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Obesity; Puberty, Precocious; Testosterone | 1991 |
Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.
Topics: 17-alpha-Hydroxypregnenolone; Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; DNA; Escherichia coli; In Vitro Techniques; Molecular Sequence Data; Pregnenolone; Progesterone; Recombinant Proteins; Spectrum Analysis; Steroid 17-alpha-Hydroxylase | 1991 |
Serum androgens in intensive-care patients: correlations with clinical findings.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adult; Androgens; Androstenedione; Bacterial Infections; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydroxyprogesterones; Intensive Care Units; Liver Diseases; Male; Middle Aged; Ovary; Severity of Illness Index; Testis; Testosterone | 1991 |
Steroidogenesis in interstitial cells and microsomal fraction of immature pig testes.
Topics: 17-alpha-Hydroxypregnenolone; Aminoglutethimide; Androgens; Androstenes; Animals; Bucladesine; Cholera Toxin; Chorionic Gonadotropin; Dehydroepiandrosterone; Male; Microsomes; Pregnenolone; Swine; Testis | 1991 |
The effects of prolonged hypertestosteronemia on adrenocortical biosynthesis in oophorectomized women.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Globulins; Humans; Hydrocortisone; Hydroxyprogesterones; Luteinizing Hormone; Middle Aged; Ovariectomy; Prolactin; Prospective Studies; Testosterone; Time Factors | 1991 |
Normal values for a short-time ACTH intravenous and intramuscular stimulation test in women in the reproductive age.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Dihydrotestosterone; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Injections, Intramuscular; Injections, Intravenous; Menstrual Cycle; Pituitary-Adrenal Function Tests; Reference Values; Testosterone; Time Factors | 1990 |
Human 3 beta-hydroxysteroid dehydrogenase/delta 5----4isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Androstenedione; Base Sequence; Dehydroepiandrosterone; DNA; Female; Gene Expression; Humans; Hydroxyprogesterones; Immunoblotting; Isomerases; Microsomes; Molecular Sequence Data; Multienzyme Complexes; NAD; Placenta; Pregnancy; Pregnenolone; Progesterone; Progesterone Reductase; Steroid Isomerases; Transfection; Tumor Cells, Cultured | 1990 |
Serum steroid hormone levels in neonates born from the mother with placental sulfatase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Dehydroepiandrosterone; Female; Fetal Blood; Gonadal Steroid Hormones; Humans; Hydrocortisone; Infant, Newborn; Male; Placenta; Pregnancy; Pregnenolone; Sulfatases | 1990 |
Nonclassical 3 beta-hydroxysteroid dehydrogenase deficiency in young girls with hirsutism and premature pubarche.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Child; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydroxyprogesterones; Paramethasone; Puberty, Precocious | 1990 |
ACTH stimulation tests and plasma dehydroepiandrosterone sulfate levels in women with hirsutism.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diagnosis, Differential; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Progesterone | 1990 |
[Clinical features and diagnosis of mild 3-beta-hydroxysteroid dehydrogenase deficiency in men].
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Body Height; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Gynecomastia; Humans; Hypogonadism; Infertility, Male; Male; Mixed Function Oxygenases | 1989 |
Biosynthetic pathways of testosterone and estradiol-17 beta in slices of the embryonic ovary and testis of the chicken (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenedione; Animals; Chick Embryo; Dehydroepiandrosterone; Estradiol; Estrogens; Female; Hydroxyprogesterones; Male; Ovary; Pregnenolone; Testis; Testosterone | 1989 |
[Elevated levels of plasma 4-ene steroids in a case of congenital deficiency of 3 beta-hydroxysteroid dehydrogenase].
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Dehydroepiandrosterone; Disorders of Sex Development; Humans; Hydrocortisone; Hydroxyprogesterones; Infant; Infant, Newborn; Male; Testosterone | 1989 |
Serum adrenal steroid concentrations in premature infants.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; Aldosterone; Androstenedione; Birth Weight; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Gestational Age; Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Infant, Newborn; Infant, Premature; Male; Steroids | 1989 |
In-vitro steroid production by human granulosa lutein cells in long-term cultures.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androstenedione; Cells, Cultured; Corpus Luteum; Dehydroepiandrosterone; Female; Granulosa Cells; Humans; Hydroxyprogesterones; Luteal Cells; Progesterone; Steroids; Time Factors | 1989 |
Steroid responses to ACTH in women with polycystic ovaries.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Cortodoxone; Cosyntropin; Dehydroepiandrosterone; Female; Heterozygote; Humans; Hydroxyprogesterones; Middle Aged; Polycystic Ovary Syndrome; Steroids | 1989 |
Effect of androgen on adrenal steroidogenesis in normal women.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Testosterone | 1988 |
Co-induction of 17 alpha-hydroxylase and C-17,20-lyase activities in primary cultures of bovine adrenocortical cells in response to ACTH treatment.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldehyde-Lyases; Animals; Bucladesine; Cattle; Cells, Cultured; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Kinetics; Microsomes; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1988 |
Identification of nonecdysteroid steroids in hemolymph of both male and female Astacus leptodactylus (Crustacea) by gas chromatography-mass spectrometry.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cholesterol; Crustacea; Dehydroepiandrosterone; Dihydrotestosterone; Female; Gas Chromatography-Mass Spectrometry; Hemolymph; Hydroxyprogesterones; Hydroxytestosterones; Male; Pregnenolone; Steroids; Testosterone | 1986 |
Intratesticular unconjugated steroids in elderly men.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adult; Aged; Androstane-3,17-diol; Androstenediol; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Reference Values; Steroids; Testis; Testosterone | 1986 |
[Relation between size of fetal and neonatal adrenal glands and steroid levels in maternal and neonatal serum].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Dehydroepiandrosterone; Estradiol; Estriol; Female; Fetal Blood; Fetal Organ Maturity; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Infant, Newborn; Pregnancy; Ultrasonography | 1987 |
Kinetic studies on the enzymes involved in estrogen biosynthesis and evidence for existence of a single 5-Ene-3beta-hydroxysteroid dehydrogenase complex in the ovary of the freshwater catfish, Clarias batrachus.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Fishes; Kinetics; Ovary; Pregnenolone; Testosterone | 1985 |
Enhanced 17 alpha-hydroxylation of pregnenolone and increased androgen production by rabbit adrenocortical cells stimulated chronically with corticotropin.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hydroxylation; In Vitro Techniques; Male; Pregnenolone; Rabbits; Stimulation, Chemical | 1986 |
Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; Acetyl Coenzyme A; Adult; Aged; Androgens; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cholesterol; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Middle Aged; Models, Chemical; Pregnenolone | 1986 |
[Age-related changes in secretion of adrenocortical steroid hormones in normal healthy men].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Aging; Cosyntropin; Dehydroepiandrosterone; Dexamethasone; Humans; Injections, Intramuscular; Male; Middle Aged; Pregnenolone; Progesterone; Radioimmunoassay | 1986 |
Response of plasma adrenal steroids to synthetic ACTH under ketoconazole in man.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldehyde-Lyases; Aldosterone; Corticosterone; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase | 1987 |
Kinetic analysis of adrenal 3 beta-hydroxysteroid dehydrogenase activity during human development.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Glands; Adult; Aging; Child; Dehydroepiandrosterone; Female; Humans; Infant; Kinetics; Male; Microsomes; Middle Aged; NAD; Pregnenolone | 1985 |
[Analytical method of delta 5-3 beta OH steroid sulfates using high performance liquid chromatography and immobilized 3beta-hydroxysteroid dehydrogenase in column form].
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Female; Humans; Pregnenolone | 1985 |
Gas chromatographic-mass spectrometric study of metabolites of C21 and C19 steroids in neonatal porcine testicular microsomes.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androstenediol; Androstenols; Animals; Animals, Newborn; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Hydroxyprogesterones; Male; Microsomes; Pregnanes; Pregnenolone; Progesterone; Swine; Testis | 1985 |
Direct solid-phase radioimmunoassay for screening 17 alpha-hydroxyprogesterone in whole-blood samples from newborns.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Animals; Cortodoxone; Cross Reactions; Dehydroepiandrosterone; Estriol; Filtration; Humans; Hydrocortisone; Hydroxyprogesterones; Infant, Newborn; Mass Screening; Progesterone; Rabbits; Radioimmunoassay | 1985 |
Response of serum testosterone and its precursor steroids, SHBG and CBG to anabolic steroid and testosterone self-administration in man.
Topics: 17-alpha-Hydroxypregnenolone; Anabolic Agents; Androgens; Androstenediol; Androstenedione; Carrier Proteins; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Kinetics; Male; Pregnenolone; Progesterone; Sex Hormone-Binding Globulin; Sports; Testosterone | 1985 |
Elevated 17-hydroxyprogesterone and testosterone in a newborn with 3-beta-hydroxysteroid dehydrogenase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 20-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Androstenedione; Cortisone Reductase; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Hypospadias; Infant, Newborn; Male; Testosterone | 1985 |
Adrenocortical carcinoma with Cushing's syndrome presenting unusual urinary 17-ketosteroid fractionation.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adult; Androstenedione; Androsterone; Cortodoxone; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Etiocholanolone; Humans; Male; Tomography, X-Ray Computed | 1985 |
Down and Klinefelter syndromes (48, XXY, G+) in a young man. Cytogenetic, endocrine, and testicular steroidogenesis studies.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Androstenols; Dehydroepiandrosterone; Down Syndrome; Estradiol; Estrone; Follicle Stimulating Hormone; Humans; Hydroxyprogesterones; In Vitro Techniques; Karyotyping; Klinefelter Syndrome; Luteinizing Hormone; Male; Progesterone; Sex Chromatin; Staining and Labeling; Testis; Testosterone | 1974 |
Metabolism of 3-beta-hydroxy-5-ene steroids by testes of rats acclimatized to a hot environment.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Acclimatization; Androstanes; Androstenedione; Androstenes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Cryptorchidism; Dehydroepiandrosterone; Hot Temperature; Hydroxyprogesterones; In Vitro Techniques; Male; NADP; Pregnenolone; Rats; Testis; Testosterone; Time Factors; Tissue Extracts | 1973 |
In vitro biosynthesis of androgens in canine testes.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Cytosol; Dehydroepiandrosterone; Dogs; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; NAD; NADP; Pregnenolone; Progesterone; Stimulation, Chemical; Testis; Testosterone; Time Factors | 1973 |
Kinetic studies on the enzymes catalysing the conversion of 17alpha-hydroxyprogesterone and dehydroepiandrosterone to androstenedione in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstenedione; Dehydroepiandrosterone; Depression, Chemical; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Kinetics; Microsomes; NAD; NADP; Oxidoreductases; Pregnenolone; Progesterone | 1974 |
Steroidogenesis in vitro by the ovarian tissue of the domestic fowl (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Autoradiography; Carbon Radioisotopes; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; In Vitro Techniques; NAD; NADP; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone; Time Factors; Tritium | 1974 |
Metabolism in vivo of steroids in the canine ovary.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Blood; Carbon Isotopes; Chromatography, Gas; Dehydroepiandrosterone; Dogs; Estradiol; Female; Hydroxyprogesterones; Ovary; Steroids; Testosterone; Tritium | 1965 |
In vitro testosterone synthesis by rat testicular tissue.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Rats; Subcellular Fractions; Testis; Testosterone | 1965 |
[Biological half-life periods of C21-steroids in guinea pigs].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Blood; Dehydroepiandrosterone; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids | 1966 |
Gas chromatographic-mass spectrometric studies on solvolyzable steroids in human peripheral plasma.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androsterone; Bile Acids and Salts; Blood Chemical Analysis; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Etiocholanolone; Humans; In Vitro Techniques; Pregnenolone; Progesterone; Spectrum Analysis; Steroids; Testosterone | 1966 |
On the biosynthesis of testicular steroids in vitro and its inhibition.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Animals; Cattle; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Male; Metyrapone; Naphthalenes; Pyridines; Rats; Testis; Testosterone | 1965 |
Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estriol; Humans; Hydroxyprogesterones; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnenolone; Sulfates | 1966 |
Excretion of 16-alpha-hydroxysteroids by premature infants.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Infant, Newborn; Infant, Premature; Liver; Male; Mixed Function Oxygenases; Steroids; Sulfatases | 1966 |
Column liquid-liquid partition chromatography of steroidal sulfates.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Cholesterol; Chromatography; Dehydroepiandrosterone; Etiocholanolone; Pregnanediol; Pregnenolone; Steroids; Sterols; Sulfates | 1966 |
Effect of steroids on germinal vesicle of oocytes of the frog (Rana pipiens) in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Aldosterone; Androgens; Animals; Anura; Cell Nucleus; Cholesterol; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Hydrocortisone; In Vitro Techniques; Ovum; Pregnanediol; Pregnenolone; Progesterone; Steroids; Testosterone | 1967 |
Testosterone biosynthesis in monkey testis.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Carbon Isotopes; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Tritium | 1967 |
Formation of dehydroepiandrosterone sulphate by previable human foetuses.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Paper; Dehydroepiandrosterone; Female; Fetus; Humans; Hydroxyprogesterones; Liver; Male; Maternal-Fetal Exchange; Perfusion; Pregnancy; Sulfates; Tritium; Umbilical Cord | 1967 |
Pathways for androgen biosynthesis in monkey testis.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1967 |
Conversion of pregnenolone-7-alpha-3H-sulfate to other delta-5-3-beta-hydroxysteroid sulfates by the human fetal adrenal in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; In Vitro Techniques; Perfusion; Pregnancy; Pregnanes; Pregnenolone; Sulfates; Tritium | 1968 |
Distribution of hydroxysteroid dehydrogenases in the placenta of the pig.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Castration; Dehydroepiandrosterone; Epithelium; Estradiol; Estrogens; Etiocholanolone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Ovary; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Swine; Trophoblasts | 1968 |
[Effect of gonadotropins on the adrenal cortex. II. Incubation of adrenal homogenates from normal and castrated guinea pigs with 7alpha-3H-cholesterol under the influence of serum gonadotropin].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Animals; Cholesterol; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Glucuronates; Glycolipids; Gonadotropins; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Sulfates; Tritium | 1967 |
Sex hormones in the ovaries of the lizard Lacerta sicula.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Lizards; Male; Ovary; Physiology, Comparative; Pregnenolone; Progesterone; Snakes; Spectrophotometry; Testis; Tissue Extracts | 1968 |
Isolation and quantitation of steroids from normal human amniotic fluid.
Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androgens; Carbon Isotopes; Chemistry, Clinical; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estranes; Estriol; Female; Fetus; Glucuronidase; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnanediol; Pregnanes; Spectrum Analysis; Steroids; Sulfatases; Tritium | 1968 |
Steroid hormone formation in the human ovary. VI. Evidence for two pathways of synthesis of androgens in the stromal compartment.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androstanes; Biotransformation; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Ovary; Pregnancy; Pregnenolone; Progesterone; Spectrophotometry; Testosterone; Tritium | 1968 |
De novo steriod sulfate biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Adrenal Glands; Androgen-Insensitivity Syndrome; Carbon Isotopes; Cholesterol; Chromatography, Paper; Crystallization; Dehydroepiandrosterone; Fetus; Humans; In Vitro Techniques; Male; Pregnanes; Pregnenolone; Sulfates; Testis | 1968 |
Metabolism of (3H) pregnenolone by adrenal glands from newborn anencephalic infants.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androstanes; Anencephaly; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Infant, Newborn; Pregnenolone; Progesterone; Sulfates; Tritium | 1968 |
Steroid biosynthesis in vitro and in tissue culture by adrenal tumours of mice of the CE strain.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Culture Techniques; Dehydroepiandrosterone; Desoxycorticosterone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; Pregnenolone; Rodent Diseases; Steroids; Tritium | 1968 |
Virilizing male pseudohermaphroditism. Association with abnormal testicular function.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Chorionic Gonadotropin; Dehydroepiandrosterone; Disorders of Sex Development; Humans; Hydroxyprogesterones; Hyperplasia; Leydig Cells; Male; Pregnenolone; Progesterone; Testis; Testosterone; Virilism | 1969 |
[In vitro experiments on steroid hormone formation in the corpus luteum, stroma, hilum and follicles of the normal human ovary].
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstanes; Autoradiography; Carbon Isotopes; Chromatography, Thin Layer; Corpus Luteum; Corpus Luteum Hormones; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone | 1968 |
Effect of vitamin A on enzymic conversion of the delta-5-3-beta-hydroxy- into delta-4-3-oxosteroids by adrenals of the rat.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Acids; Adrenal Glands; Age Factors; Androstanes; Animals; Body Weight; Castration; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Organ Size; Ovary; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Vitamin A; Vitamin A Deficiency; Weaning | 1969 |
Further studies on the relationship between C19- and C21-steroid synthesis in the human adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Breast Neoplasms; Carbon Isotopes; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Testosterone; Transferases; Tritium | 1969 |
Nonenzymic conversion of 17 alpha-hydroxypregnenolone into dehydroepiandrosterone.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Chemical Phenomena; Chemistry; Chromatography, Gas; Crystallization; Dehydroepiandrosterone; Lead; Pregnanes | 1970 |
Adrenal function in breast cancer: biogenesis of androgens and cortisol by the human adrenal gland in vivo.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aged; Androgens; Androstanes; Androsterone; Breast Neoplasms; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovary; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium | 1970 |
Identification and determination of neutral steroid sulphates in human foetal adrenal and liver tissue.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androstanes; Chromatography, Gas; Dehydroepiandrosterone; Fetus; Gestational Age; Humans; Liver; Pregnanes; Pregnenolone; Progesterone; Tissue Extracts | 1970 |
The metabolism of steroids in the rabbit epididymis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Acetates; Androstanes; Animals; Carbon Isotopes; Chorionic Gonadotropin; Crystallization; Dehydroepiandrosterone; Epididymis; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; Pregnanes; Pregnenolone; Progesterone; Rabbits; Sterols; Testosterone; Tritium | 1970 |
Pathways of dehydroepiandrosterone sulphate biosynthesis in the human foetal adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Gas; Dehydroepiandrosterone; Fetus; Humans; In Vitro Techniques; Kinetics; Pregnenolone; Radioisotope Dilution Technique; Spectrum Analysis; Sulfates; Tritium | 1970 |
Steroids of invertebrates. V. The in vitro biosynthesis of steroids by the male-phase ovotestis of the slug (Ariolimax californicus).
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Animals; Biotransformation; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Crustacea; Dehydroepiandrosterone; Female; Gonads; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Insecta; Male; Mollusca; Pregnenolone; Snails; Steroids; Tritium | 1970 |
Pregnenolone and pregnenolone sulfate metabolism by human fetal testes in vitro.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Fetus; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Sulfatases; Sulfates; Testis; Tritium | 1970 |
Blood levels and production rate of 17-hydroxypregnenolone in man.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Thin Layer; Circadian Rhythm; Dehydroepiandrosterone; Dexamethasone; Estradiol; Female; Fluoxymesterone; Humans; Hydroxyprogesterones; Male; Menstruation; Metabolic Clearance Rate; Methods; Pregnanes; Protein Binding; Sex Factors; Testis; Testosterone | 1970 |
The biogenesis of androgens and cortisol by the human adrenal gland in vivo.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones | 1970 |
Studies on the inhibition of fetal androgen formation. Inhibition of testosterone synthesis in rat and rabbit fetal testes with observations on reproductive tract development.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Abnormalities, Drug-Induced; Androstanes; Animals; Carbon Isotopes; Cholestanes; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Depression, Chemical; Female; Fetus; Genitalia, Male; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Hypospadias; In Vitro Techniques; Indenes; Male; Perineum; Pregnancy; Pregnenolone; Pyridines; Rabbits; Rats; Testis; Testosterone; Wolffian Ducts | 1971 |
Steroids and sterols in meconium.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Androsterone; Bile; Chromatography; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Fetus; Glucuronates; Humans; Infant, Newborn; Intestine, Small; Maternal-Fetal Exchange; Meconium; Placenta; Pregnancy; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sterols; Testosterone | 1971 |
Adrenal biogenesis in vivo of androgens and cortisol in the guinea-pig using a continuous infusion technique.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androgens; Androstanes; Animals; Carbon Isotopes; Dehydroepiandrosterone; Female; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Methods; Pregnenolone; Progesterone; Tritium | 1971 |
The in vitro formation of androstenedione from C 21 steroids by follicles isolated from human ovaries. A time study.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adult; Androstanes; Carbon Isotopes; Crystallization; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Ovarian Follicle; Ovary; Pregnenolone; Progesterone; Time Factors; Tritium | 1971 |
The separation of C19-16-unsaturated steroids from C21 and other C19-steroids by two-dimensional thin-layer chromatography.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstanes; Androsterone; Autoradiography; Chromatography, Thin Layer; Dehydroepiandrosterone; Estrogens; Etiocholanolone; Hydroxyprogesterones; Methods; Pregnenolone; Progestins; Testosterone | 1971 |
Metabolism of pregnenolone and dehydroepiandrosterone by homogenized tissue from the separated zones and whole adrenal glands from newborn anencephalic infants.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenosine Triphosphate; Adrenal Glands; Androstanes; Anencephaly; Dehydroepiandrosterone; Estrogens; Female; Fetus; Humans; Hydroxysteroid Dehydrogenases; Infant, Newborn; Isomerases; Lyases; Male; Mixed Function Oxygenases; Pregnenolone; Sulfates; Sulfurtransferases; Tritium | 1971 |
Site of dehydroepiandrosterone sulphate biosynthesis in the adrenal gland of the previable foetus.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Thin Layer; Dehydroepiandrosterone; Fetus; Freezing; Humans; In Vitro Techniques; Male; Pregnenolone; Sulfates; Tritium | 1971 |
[Steroid-hormones in the guinea pig].
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Animals; Body Weight; Chemotherapy, Cancer, Regional Perfusion; Dehydroepiandrosterone; Glucuronates; Guinea Pigs; Half-Life; Hydrocortisone; Kidney; Liver; Liver Circulation; Mononuclear Phagocyte System; Pregnenolone; Progesterone; Sulfates; Sulfoglycosphingolipids; Tritium | 1971 |
Studies of the human testis. I. Biosynthetic pathways for androgen formation in human testicular tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Aged; Androstanes; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone; Time Factors; Tritium | 1972 |
Steroid biosynthesis in vitro by gonadal tissues in true hermaphroditism.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Dehydroepiandrosterone; Disorders of Sex Development; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Ovary; Pregnanes; Pregnenolone; Progesterone; Sterols; Testis; Testosterone; Tritium | 1972 |
Free and sulfate-conjugated neutral steroids in human testis tissue.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Aged; Androstanes; Androsterone; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Humans; Hydroxysteroids; Ketosteroids; Male; Mass Spectrometry; Middle Aged; Pregnanediol; Pregnanes; Pregnenolone; Steroids; Sulfuric Acids; Testis; Testosterone | 1972 |
Comparative ultrastructural and histochemical studies of the interstitial cells of the rat testis during fetal and postnatal development.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cell Nucleolus; Dehydroepiandrosterone; Endoplasmic Reticulum; Golgi Apparatus; Histocytochemistry; Hydroxysteroid Dehydrogenases; Lipids; Male; Microscopy, Electron; Mitochondria; Pregnenolone; Rats; Testis | 1972 |
17 -hydroperoxypregnenes. 3. Studies on their role as possible precursors in the biosynthesis of adrenosteroid hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Aerobiosis; Anaerobiosis; Androstanes; Animals; Cattle; Chloromercuribenzoates; Chromatography, Gas; Dehydroepiandrosterone; Drug Stability; Glucocorticoids; Hot Temperature; Hydroxyprogesterones; Kinetics; Mass Spectrometry; Peroxides; Pregnenolone; Progesterone | 1972 |
Subcellular localization of the adrenal desmolase active in the formation of dehydroepiandrosterone (3 -hydroxy-5-androsten-17-one).
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Animals; Carbon Isotopes; Centrifugation; Dehydroepiandrosterone; Guinea Pigs; Histocytochemistry; Lyases; Male; Microsomes; Mitochondria; Spectrum Analysis; Ultraviolet Rays | 1971 |
Biosynthesis of steroid hormones by testes and ovaries of the peludo, Chaetophractus villosus (Edentata, mammalia).
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Dehydroepiandrosterone; Female; Male; Ovary; Pregnancy; Pregnanes; Pregnenolone; Progesterone; Testis; Xenarthra | 1972 |
Conversion of pregnenolone and pregnenolone sulfate to other steroid sulfates by the human fetus perfused at midgestation.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Carbon Isotopes; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Liver; Perfusion; Pregnancy; Pregnenolone; Sulfates; Tritium | 1972 |
Steroid metabolism in kidney tissue. I. Endogenous neutral steroids in foetal kidneys and studies on their formation.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Buffers; Chromatography; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydroxyprogesterones; In Vitro Techniques; Kidney; Mass Spectrometry; Methods; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfates; Sulfurtransferases; Time Factors | 1972 |
In vitro steroidogenesis by testes of the chicken (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenes; Animals; Cell Fractionation; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Isomerases; Male; Microsomes; Oxidoreductases; Pregnenolone; Steroid Hydroxylases; Testis; Testosterone | 1972 |
In vitro metabolism of a mixture of (4- 14 C)pregnenolone and (17 - 3 H)pregnenolone by polycystic ovary: pathways of testosterone biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstenes; Carbon Isotopes; Chromatography, Paper; Crystallization; Cysts; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Ovarian Diseases; Ovary; Pregnenolone; Progesterone; Testosterone; Tritium | 1972 |
Adrenal steroid biosynthesis from 4-14C-cholesterol (in vitro) during phenobarbital block of PMS-induced ovulation in immature rats.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Cholesterol; Chorionic Gonadotropin; Chromatography, Gas; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Gonadotropins, Equine; Hydroxyprogesterones; In Vitro Techniques; Ovulation; Phenobarbital; Pregnenolone; Progesterone; Rats | 1973 |
Elimination of tritium from metabolites of (16- 3 H)-pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androstenedione; Animals; Carbon Isotopes; Dehydroepiandrosterone; Hydrolysis; In Vitro Techniques; Male; Pregnenolone; Rabbits; Testis; Testosterone; Tritium | 1973 |
Histochemical localization of 3 - and 17 -hydroxysteroid dehydrogenases in the male reprodutive tract of the domestic fowl (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Animals; Chickens; Dehydroepiandrosterone; Epididymis; Genitalia, Male; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Microscopy; Pregnenolone; Seminal Vesicles; Testis; Vas Deferens | 1973 |
The metabolic fate of pregnenolone-7 - 3 H and pregesterone-4- 14 C in the ovaries and fat bodies of female Triturus cristatus carnifex.
Topics: 17-alpha-Hydroxypregnenolone; Adipose Tissue; Animals; Carbon Isotopes; Castration; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Ovary; Pregnenolone; Progesterone; Seasons; Time Factors; Tritium; Triturus | 1973 |
Radioimmunoassay of plasma pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone under various physiological conditions.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Child; Chromatography; Climacteric; Dehydroepiandrosterone; Female; Humans; Immune Sera; Infant, Newborn; Male; Menstruation; Methods; Pregnancy; Pregnenolone; Puberty; Radioimmunoassay | 1973 |
Some effects of steroids on the immature mouse ovary in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Culture Techniques; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; Mice; Mitosis; Ovarian Follicle; Ovary; Pregnenolone; Progesterone; Steroids; Stimulation, Chemical; Testosterone; Thymidine; Tritium | 1973 |
Serum steroid levels during the menstrual cycle in a bilaterally adrenalectomized woman.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Gland Diseases; Adrenalectomy; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Menstruation; Ovary; Pregnenolone; Progesterone; Testosterone | 1973 |
Glucocorticoid synthesis from pregnenolone by sheep foetal adrenals in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstenedione; Animals; Chromatography; Corticosterone; Dehydroepiandrosterone; Fetus; Gestational Age; Glucocorticoids; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Sheep | 1973 |
In vitro metabolism of (4-14C) pregnenolone in the ovaries of intact and HPL or HCG treated rats.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Animals; Carbon Radioisotopes; Chorionic Gonadotropin; Chromatography, Paper; Dehydroepiandrosterone; Drug Synergism; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Hypophysectomy; Ovary; Placental Lactogen; Pregnenolone; Progesterone; Rats; Steroids; Testosterone | 1973 |
Endogenous steroid sulphates and glucuronides in the gallbladder bile from early and mid-term human foetuses.
Topics: 17-alpha-Hydroxypregnenolone; Androstenes; Bile; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gallbladder; Glucuronates; Humans; Mass Spectrometry; Pregnancy; Pregnanediol; Pregnanetriol; Pregnenolone; Steroids; Sulfates | 1973 |
Formation of neutral steroids from endogenous precursors in minced human fetal adrenals in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Female; Fetus; Humans; Mass Spectrometry; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfuric Acids; Time Factors | 1974 |
The in vitro biosynthesis of steroids by the gonad of the mussel (Mytilus edulis).
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Bivalvia; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Gonads; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Ovary; Oxidation-Reduction; Pregnenolone; Progesterone; Radioimmunoassay; Testis; Testosterone; Tritium | 1974 |
The annual testicular cycle and androgen production in vitro in the masked civet cat, Paguma l. larvata.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Carnivora; Dehydroepiandrosterone; Histocytochemistry; Hydroxyprogesterones; In Vitro Techniques; Lipids; Male; Organ Size; Pregnenolone; Progesterone; Seasons; Spermatogenesis; Testis; Testosterone | 1974 |
Augmentation of the rat uterine weight response to human chorionic gonadotrophin by various steroids.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Androsterone; Animals; Body Weight; Castration; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Organ Size; Ovary; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Testosterone; Uterus | 1974 |
The biosynthesis of estrogens by cow follicles.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Biotransformation; Cattle; Cells, Cultured; Chromatography; Dehydroepiandrosterone; Estrogens; Female; Manometry; Ovarian Follicle; Pregnenolone; Progesterone; Tritium | 1974 |
Effect of maternal intrahepatic cholestasis on fetal steroid metabolism.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Androsterone; Birth Weight; Cholestasis; Dehydroepiandrosterone; Estriol; Female; Fetus; Gestational Age; Humans; Hydroxylation; Male; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications; Pregnanediol; Pregnanetriol; Pregnenolone; Progesterone; Steroids; Umbilical Cord | 1974 |
Simultaneous estimation of pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone by gas-liquid radiochromatography.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenalectomy; Breast Neoplasms; Carbon Radioisotopes; Chromatography, Gas; Dehydroepiandrosterone; Evaluation Studies as Topic; Female; Humans; Methods; Microsomes; Pregnenolone; Tritium | 1974 |
Plasma steroids in congenital adrenal hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Androstenediols; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Progesterone; Steroids | 1974 |
Studies on the inhibition by 5alpha-pregnane-3,20-dione of the biosynthesis of 16-androstenes and dehydroepiandrosterone in boar testis preparations.
Topics: 17-alpha-Hydroxypregnenolone; Androstadienes; Androstenes; Animals; Carbon Radioisotopes; Cell Fractionation; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Drug Stability; Freezing; Kinetics; Male; Microsomes; Oxidoreductases; Pregnenolone; Progesterone; Swine; Testis; Ultracentrifugation | 1974 |
Androgen formation from pregnenolone sulfate by the human fetal ovary.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Androstenedione; Body Weight; Carbon Radioisotopes; Chromatography, Paper; Dehydroepiandrosterone; Female; Gestational Age; Humans; Liver; Ovary; Pregnenolone; Tritium | 1974 |
Tumors of dysgenetic gonads (gonadoblastoma): ultrastructural and steroidogenic aspects.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Androstenes; Basement Membrane; Cell Nucleus; Cytoplasm; Dehydroepiandrosterone; Dysgerminoma; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Testosterone; Turner Syndrome | 1974 |
[Histoenzymology of the ovary of the pregnant and non-pregnant cat: importance of interstitial tissue].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cats; Corpus Luteum; Dehydroepiandrosterone; Estradiol; Female; Hydroxysteroid Dehydrogenases; Ovary; Pregnancy; Pregnenolone; Progesterone; Succinate Dehydrogenase; Testosterone; Time Factors | 1973 |
Steroid hydroxylations. V. Intracellular location of 16alpha-hydroxylase and its substrate specificity in sow ovary.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Chromatography, Paper; Dehydroepiandrosterone; Female; Hydroxyprogesterones; In Vitro Techniques; Mixed Function Oxygenases; Ovary; Periodic Acid; Pregnenolone; Progesterone; Swine; Testosterone | 1966 |
Androgen synthesis in a patient with virilizing adrenocortical carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Carbon Isotopes; Chromatography; Culture Techniques; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Testosterone | 1967 |
Inhibition of adrenal cortical secretion by amino-glutethimide in dogs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Chromatography, Paper; Corticosterone; Dehydroepiandrosterone; Depression, Chemical; Desoxycorticosterone; Dogs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Pyridones; Veins | 1968 |
The effect of exogenous corticotrophin on steroid excretion in the newborn.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androgens; Chemistry, Clinical; Chromatography, Thin Layer; Dehydroepiandrosterone; Dyspepsia; Feeding and Eating Disorders; Humans; Hydrocortisone; Hyperbilirubinemia; Infant, Newborn; Infant, Premature; Laryngitis; Male; Pregnanes; Pregnenolone; Shock; Stimulation, Chemical | 1968 |
Possible role of cyclic AMP in the short term regulation of adrenal steroidogenesis.
Topics: 17-alpha-Hydroxypregnenolone; Adenine Nucleotides; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Animals; Cholesterol; Corticosterone; Cyclic AMP; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids | 1971 |
Biosynthesis and secretion of steroids by the canine testis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Chorionic Gonadotropin; Cyclic AMP; Dehydroepiandrosterone; Dogs; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Tritium | 1971 |
Steroid biosynthesis by transplantable gonadal tumors of rat.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Bucladesine; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Granulosa Cell Tumor; Hydroxyprogesterones; Luteinizing Hormone; Male; Neoplasm Transplantation; Ovarian Neoplasms; Pregnenolone; Progesterone; Rats; Spectrophotometry, Ultraviolet; Testicular Neoplasms; Testosterone; Transplantation, Homologous; Tritium | 1973 |
Stimulation of the rat ovary by gonadotropins and separation of steroids by gas chromatography.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Cholesterol; Chorionic Gonadotropin; Chromatography, Gas; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Follicle Stimulating Hormone; Glucosephosphate Dehydrogenase; Gonadotropins, Equine; Hydroxyprogesterones; In Vitro Techniques; Luteinizing Hormone; NADP; Nandrolone; Ovary; Pregnenolone; Progesterone; Rats; Subcellular Fractions; Testosterone | 1965 |
Conversion of 17-alpha-hydroxypregnenolone to dehydroepiandrosterone by adrenal homogenates of immature and adult guinea pigs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Aging; Animals; Animals, Newborn; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dehydroepiandrosterone; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; NADP; Pregnenolone; Tritium | 1967 |
Histochemical distribution of some hydroxysteroid dehydrogenases in the placenta, foetal membranes and uterine mucosa of the mouse.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Dehydroepiandrosterone; Endometrium; Estradiol; Extraembryonic Membranes; Female; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; NAD; NADP; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Testosterone | 1968 |
Androgen production in vitro by phalarope gonadal tissue homogenates.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Birds; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; NADP; Ovary; Pregnanes; Pregnenolone; Testis; Testosterone; Tritium | 1968 |
Effect of diethylstilbestrol on enzymes of cryptochid mouse testes of Balb-c mice.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Cryptorchidism; Dehydroepiandrosterone; Depression, Chemical; Diethylstilbestrol; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cells; Lyases; Male; Mice; Microsomes; Mixed Function Oxygenases; Pregnenolone; Progesterone; Testis; Testosterone | 1969 |
Steroid biosynthesis by the equine testis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Age Factors; Androstanes; Animals; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Haplorhini; Horses; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Leydig Cells; Lyases; Male; Mice; Mixed Function Oxygenases; NADP; Physiology, Comparative; Pregnenolone; Testis; Testosterone; Tritium | 1969 |
Some aspects of the control of dehydroepiandrosterone synthesis in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Carbon Isotopes; Chromatography; Dehydroepiandrosterone; Endoplasmic Reticulum; Female; Humans; In Vitro Techniques; Kinetics; Male; Microsomes; NADP; Tritium | 1971 |
Effects of pinealectomy on the testicular function of the adult male duck.
Topics: 17-alpha-Hydroxypregnenolone; Analysis of Variance; Androstanes; Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Ducks; Hydroxyprogesterones; Male; NADP; Organ Size; Pineal Gland; Pregnenolone; Progesterone; Progestins; Seasons; Testis; Testosterone | 1971 |
Enzymes of androgen biosynthesis in the desert mouse Gerbillus dasyurus.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Body Weight; Chromatography, Paper; Crystallization; Dehydroepiandrosterone; Desert Climate; Gerbillinae; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; NADP; Organ Size; Testis; Testosterone | 1972 |
Some aspects of the control of dehydroepiandrosterone synthesis in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstanols; Carbon Isotopes; Chromatography, Paper; Cyproterone; Dehydroepiandrosterone; Female; Humans; Hydroxylation; In Vitro Techniques; Kinetics; NADP; Pregnenolone; Subcellular Fractions | 1972 |
Pathways for androgen synthesis in vitro by the testes of Japanese quail (Coturnix coturnix japonica).
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androstanes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Coturnix; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Male; NAD; NADP; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1972 |
Steroid 16 alpha-hydroxylase from human fetal liver; inhibition by steroids.
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenols; Aryl Hydrocarbon Hydroxylases; Chlormadinone Acetate; Dehydroepiandrosterone; Estradiol; Estrone; Ethinyl Estradiol; Humans; Liver; Mestranol; Norethindrone; Pregnenolone; Progesterone; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1980 |
Plasma androgens in women with acne vulgaris.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adolescent; Adult; Androgens; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydroxyprogesterones; Hydroxysteroids; Menstruation Disturbances; Sex Hormone-Binding Globulin; Testosterone | 1983 |
Characterization of the major steroids present in amniotic fluid obtained between the 15th and 17th weeks of gestation.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Amniotic Fluid; Corticosterone; Dehydroepiandrosterone; Estriol; Gestational Age; Glucuronates; Humans; Hydrocortisone; Progesterone; Sulfates | 1983 |
Comparison of serum steroid responses to a single injection of hCG in man and rat.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androgens; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Humans; Kinetics; Male; Progesterone; Rats; Rats, Inbred Strains; Species Specificity; Testosterone | 1983 |
Testicular steroidogenesis in the camel (Camelus dromedarius) during the mating and the nonmating seasons.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenediols; Androstenedione; Animals; Camelus; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Progesterone; Sexual Behavior, Animal; Steroid Hydroxylases; Testis; Testosterone | 1983 |
Steroid concentrations in the outer and inner zones of the adrenal cortex of the guinea pig.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Androstenedione; Animals; Dehydroepiandrosterone; Guinea Pigs; Male; Pregnenediones; Pregnenes; Pregnenolone; Tissue Distribution | 1984 |
Placental steroid sulfatase deficiency: biochemical diagnosis and clinical review.
Topics: 17-alpha-Hydroxypregnenolone; Amniocentesis; Androstenols; Birth Weight; Dehydroepiandrosterone; Female; Humans; Ichthyosis; Infant, Newborn; Male; Placenta; Pregnancy; Pregnancy Trimester, Third; Prenatal Diagnosis; Steryl-Sulfatase; Sulfatases | 1984 |
Modifications in the testis steroidogenic pathways in rats fed with cottonseed flour.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androgens; Animals; Cottonseed Oil; Dehydroepiandrosterone; Diet; Gossypol; Hydroxyprogesterones; Male; Mice; Mice, Inbred Strains; Pregnenolone; Rats; Testis; Testosterone | 1984 |
[Fetal hormonology by direct sampling of fetal blood during the 2d trimester of pregnancy. Study of fetal and maternal 5-ene steroid sulfates].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Blood Specimen Collection; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Prenatal Diagnosis | 1984 |
Steroid metabolism in corpora lutea of the western spotted skunk (Spilogale putorius latifrons).
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Carnivora; Corpus Luteum; Dehydroepiandrosterone; Embryo Implantation, Delayed; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Mephitidae; Pregnancy; Pregnenolone; Progesterone; Testosterone | 1984 |
Abnormal adrenal responses to adrenocorticotropic hormone in hyperandrogenic women.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; Pregnenolone; Testosterone; Time Factors | 1980 |
Inhibition of adrenal steroidogenesis by danazol in vivo.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenedione; Cortodoxone; Danazol; Dehydroepiandrosterone; Female; Humans; Pregnadienes; Pregnenolone; Progesterone; Steroids; Time Factors | 1980 |
Familial male pseudohermaphroditism due to 17-20-desmolase deficiency. I. In vivo endocrine studies.
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldehyde-Lyases; Androstenedione; Child; Chorionic Gonadotropin; Dehydroepiandrosterone; Dexamethasone; Disorders of Sex Development; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Karyotyping; Male; Menstruation; Pedigree; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone | 1980 |
Adrenarche: changing adrenal response to adrenocorticotropin.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Humans; Hydroxyprogesterones; Male; Sexual Maturation | 1981 |
The control of steroidogenesis by human fetal adrenal cells in tissue culture. I. Responses to adrenocorticotropin.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Culture Techniques; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Gonadal Steroid Hormones; Humans; Hydrocortisone | 1981 |
Evidence for reduced 3 beta-ol-hydroxysteroid dehydrogenase activity in some hirsute women thought to have polycystic ovary syndrome.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenocorticotropic Hormone; Adult; Androstenediol; Androstenediols; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Hirsutism; Humans; Kinetics; Oligomenorrhea; Polycystic Ovary Syndrome | 1981 |
Studies on ovarian and adrenal studies at different phases of the menstrual cycle. IV. The effect of dexamethasone suppression and subsequent ACTH stimulation at different phases of the menstrual cycle and following the administration of 150 mg of depot-m
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Delayed-Action Preparations; Dexamethasone; Estradiol; Female; Humans; Hydrocortisone; Luteinizing Hormone; Medroxyprogesterone; Medroxyprogesterone Acetate; Menstruation; Ovary; Pregnenolone; Progesterone; Steroids | 1981 |
Adrenocortical function in old age: response to acute adrenocorticotropin stimulation.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androstenedione; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone | 1982 |
Time trend analysis of plasma unconjugated and sulfoconjugated estrone and 3 beta-delta 5-steroids in fetal and maternal sheep plasma in relation to spontaneous parturition at term.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Dehydroepiandrosterone; Estrogens, Conjugated (USP); Estrone; Female; Fetal Blood; Gestational Age; Labor, Obstetric; Pregnancy; Pregnancy, Animal; Pregnenolone; Progestins; Sheep; Sulfates | 1982 |
Steroidogenesis in dispersed cells of human fetal adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Cyanoketone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Pituitary Hormones; Pregnenolone; Steroid 17-alpha-Hydroxylase; Tetrahydronaphthalenes | 1983 |
The response of several adrenocortical steroids to the administration of ACTH in hirsute women.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones | 1983 |
The prevalence and significance of elevated dehydroepiandrosterone sulfate levels in anovulatory women.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Anovulation; Cholesterol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans | 1984 |
In-vitro synthesis of androgen from pregnenolone in the testes of the goat (Capra hircus) and identification of 5-pregnene-3beta,17alpha,20alpha-triol as an intermediate in the metabolic pathway of pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Animals; Cell-Free System; Dehydroepiandrosterone; Goats; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenes; Pregnenolone; Progesterone; Testis; Testosterone | 1980 |
Amniotic fluid concentrations of delta 5 and delta 4 steroids in fetuses with congenital adrenal hyperplasia due to 21 hydroxylase deficiency and in anencephalic fetuses.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Hyperplasia, Congenital; Amniotic Fluid; Androstenedione; Anencephaly; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydroxyprogesterones; Male; Pregnancy; Steroid Hydroxylases; Testosterone | 1980 |
Cryptic 21-hydroxylase deficiency in families of patients with classical congenital adrenal hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Hyperplasia, Congenital; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Female; HLA Antigens; Humans; Hydroxyprogesterones; Infant; Infant, Newborn; Male; Pedigree; Steroid 21-Hydroxylase; Steroid Hydroxylases; Testosterone | 1980 |
A combined radioimmunoassay for the measurement of unconjugated and sulfoconjugated pregnenolone, 17 hydroxypregnenolone, dehydroepiandrosterone, and estrone applied to fetal and maternal ovine plasma.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Dehydroepiandrosterone; Estrone; Female; Fetal Blood; Pregnancy; Pregnenolone; Radioimmunoassay; Sheep | 1981 |
Serum steroid levels in children at birth and in early neonatal period.
Topics: 17-alpha-Hydroxypregnenolone; Adaptation, Physiological; Adrenal Cortex; Cortisone; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Infant, Newborn; Pregnenolone; Progesterone; Steroids | 1981 |
Side-chain cleavage of C21 steroids to C19 steroids by testicular microsomal cytochrome P-450: 17alpha-hydroxy C21 steroids as obligatory intermediates.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Microsomes; Pregnenolone; Progesterone; Swine; Testis | 1981 |
[A study of 16 alpha OH-DHA and 16 alpha OH-pregnenolone in feto-placental unit (author's transl)].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Anencephaly; Dehydroepiandrosterone; Female; Fetal Blood; Fetal Death; Fetal Distress; Humans; Male; Organ Culture Techniques; Placenta; Pregnancy | 1982 |
Early polycystic ovary-like syndrome in girls with central precocious puberty and exaggerated adrenal response.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenocorticotropic Hormone; Androstenedione; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydroxyprogesterones; Luteinizing Hormone; Polycystic Ovary Syndrome; Puberty, Precocious; Testosterone; Ultrasonography | 1995 |
High prevalence of abnormal adrenal response in girls with central precocious puberty at early pubertal stages.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Androstenedione; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydroxyprogesterones; Luteinizing Hormone; Puberty, Precocious; Reference Values; Testosterone | 1995 |
Testicular steroidogenesis in adult men with human chorionic gonadotropin-producing tumors.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adult; Analysis of Variance; Androgens; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Middle Aged; Reference Values; Regression Analysis; Testicular Neoplasms; Testis; Testosterone | 1995 |
Dehydroepiandrosterone reduces progressive dermal ischemia caused by thermal injury.
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Animals; Back; Burns; Dehydroepiandrosterone; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Estradiol; Ischemia; Male; Mice; Mice, Inbred BALB C; Necrosis; Random Allocation; Skin; Time Factors | 1995 |
Incorporation of bovine adrenal 3 beta-hydroxy-5-ene steroid dehydrogenase/delta 5-delta 4 isomerase into phospholipid vesicles.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Animals; Cattle; Centrifugation, Density Gradient; Cholic Acid; Cholic Acids; Chromatography, Gel; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Stability; Kinetics; Liposomes; Microsomes; Multienzyme Complexes; NAD; Phospholipids; Pregnenolone; Progesterone Reductase; Spectrophotometry; Steroid Isomerases | 1995 |
'Exaggerated adrenarche' in children presenting with premature adrenarche.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Diseases; Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Age Determination by Skeleton; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydroxyprogesterones; Male; Retrospective Studies; Testosterone | 1995 |
The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androgens; Androstenedione; Cell Membrane; Cytochrome P-450 Enzyme System; Cytochromes b5; Dehydroepiandrosterone; Escherichia coli; Humans; Hydroxyprogesterones; Kinetics; Pregnenolone; Progesterone; Recombinant Proteins; Steroid 17-alpha-Hydroxylase | 1995 |
Hirsutism and acne in women: coordinated radioimmunoassays for eight relevant plasma steroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adolescent; Adult; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Female; Follicular Phase; Hirsutism; Humans; Hydroxyprogesterones; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Steroids; Testosterone | 1994 |
Isolated precocious pubarche: an approach.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Androstenedione; Child; Dehydroepiandrosterone; Diagnosis, Differential; Female; HLA-B Antigens; HLA-B14 Antigen; HLA-DR1 Antigen; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Puberty; Puberty, Precocious; Testosterone | 1994 |
[3 beta-hydroxysteroid dehydrogenase defect: frequency of presentation in a sample of Chilean hirsute women].
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenocorticotropic Hormone; Biomarkers; Case-Control Studies; Chile; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Radioimmunoassay; Testosterone | 1993 |
Tetrapropylammonium perruthenate as a mild and efficient oxidant for sensitive steroidal alcohols.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alcohols; Androstenedione; Cyclic N-Oxides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hydroxyprogesterones; Ketones; Morpholines; Organometallic Compounds; Oxidants; Oxidation-Reduction; Pregnenediones; Pregnenolone; Quaternary Ammonium Compounds; Ruthenium; Steroids | 1993 |
Ovarian steroidogenic responses to gonadotropin-releasing hormone agonist testing with nafarelin in hirsute women with adrenal responses to adrenocorticotropin suggestive of 3 beta-hydroxy-delta 5-steroid dehydrogenase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydroxyprogesterones; Kinetics; Nafarelin; Ovary; Steroids; Testosterone | 1993 |
3 beta-hydroxysteroid dehydrogenase deficiency in hyperandrogenism.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Androgens; Androstenedione; Cosyntropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Follicle Stimulating Hormone; Humans; Hydroxyprogesterones; Luteinizing Hormone; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone | 1993 |
Pituitary-ovarian responses to leuprolide acetate testing in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Androstenedione; Dehydroepiandrosterone; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hydroxyprogesterones; Kinetics; Leuprolide; Luteinizing Hormone; Ovary; Pituitary Gland; Testosterone | 1996 |
Insulin infusion amplifies 17 alpha-hydroxycorticosteroid intermediates response to adrenocorticotropin in hyperandrogenic women: apparent relative impairment of 17,20-lyase activity.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Female; Hormones; Humans; Hyperandrogenism; Hyperinsulinism; Insulin; Steroid 17-alpha-Hydroxylase | 1996 |
Studies of 3 beta-hydroxysteroid dehydrogenase genes in infants and children manifesting premature pubarche and increased adrenocorticotropin-stimulated delta 5-steroid levels.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Androstenedione; Case-Control Studies; Child; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Infant; Male; Mutation; Polymerase Chain Reaction; Puberty, Precocious | 1996 |
Girls diagnosed with premature pubarche show an exaggerated ovarian androgen synthesis from the early stages of puberty: evidence from gonadotropin-releasing hormone agonist testing.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Androgens; Androstenedione; Child; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Follicle Stimulating Hormone; Humans; Leuprolide; Luteinizing Hormone; Ovary; Puberty, Precocious; Testosterone | 1997 |
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Brain; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 7; Dehydroepiandrosterone; DNA, Complementary; Genetic Vectors; HeLa Cells; Hippocampus; Humans; Kinetics; Mice; Rats; Recombinant Proteins; Steroid Hydroxylases; Substrate Specificity; Transfection; Vaccinia virus | 1997 |
[Defects of adrenal steroidogenesis in patients with hirsutism].
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Anabolic Agents; Androstenediol; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Luteinizing Hormone; Menstrual Cycle; Middle Aged; Progesterone; Prolactin; Radioimmunoassay; Testosterone | 1998 |
Effects of long-term growth hormone therapy on adrenal steroidogenesis in Turner syndrome.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Human Growth Hormone; Humans; Hydrocortisone; Insulin-Like Growth Factor I; Time Factors; Turner Syndrome | 1998 |
Androstenedione and progesterone production in vitro by the inner or the outer theca cells in preovulatory follicles of gonadotropin stimulated calves.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cattle; Cells, Cultured; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Hydroxycholesterols; Ovarian Follicle; Ovulation; Pregnenolone; Progesterone; Theca Cells; Time Factors | 1998 |
Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
Topics: 17-alpha-Hydroxypregnenolone; Amino Acid Sequence; Animals; Binding Sites; Dehydroepiandrosterone; Evolution, Molecular; Guinea Pigs; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Homology, Amino Acid; Species Specificity; Steroid 17-alpha-Hydroxylase; Steroids; Substrate Specificity | 1998 |
Virilizing adrenocortical adenoma: in vitro steroidogenesis, immunohistochemical studies of steroidogenic enzymes, and gene expression of corticotropin receptor.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Adult; Blotting, Northern; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Female; Follow-Up Studies; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Immunohistochemistry; Receptors, Corticotropin; RNA, Messenger; Virilism | 1999 |
Apparent activities of 21-hydroxylase, 17alpha-hydroxylase and 17,20-lyase are impaired in adrenal incidentalomas.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Aldosterone; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Progesterone; Prospective Studies; Renin; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase | 1999 |
Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Cell Line; Cytochromes b5; Dehydroepiandrosterone; Humans; Kidney; NADPH-Ferrihemoprotein Reductase; Pregnenolone; Recombinant Fusion Proteins; Steroid 17-alpha-Hydroxylase; Transfection | 2000 |
Adrenocortical hyperresponsivity to adrenocorticotropic hormone: a mechanism favoring the normal production of cortisol in 21-hydroxylase-deficient nonclassic adrenal hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Cortodoxone; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydrocortisone; Pregnenolone; Progesterone; Prospective Studies; Steroid 21-Hydroxylase | 2000 |
Effect of follicle-stimulating hormone on ovarian androgen production in a woman with isolated follicle-stimulating hormone deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Female; Follicle Stimulating Hormone; Humans; Mutation; Ovary; Testosterone | 2000 |
The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central-type benzodiazepine receptors.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Animals; Carbolines; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Diazepam Binding Inhibitor; Dihydrotestosterone; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hydroxysteroids; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Ligands; Male; Neuroglia; Neurons; Neuropeptides; Peptide Fragments; Pregnenolone; Progesterone; Rana ridibunda; Receptors, GABA-A | 2001 |
Increased adrenal steroid secretion in response to CRF in women with hypothalamic amenorrhea.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Amenorrhea; Androgens; Case-Control Studies; Corticotropin-Releasing Hormone; Cortodoxone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hypothalamic Diseases; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Steroids | 2001 |
Hormonal steroidogenesis in liver and small intestine of the green frog, Rana esculenta L.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenediol; Androstenedione; Animals; Autoradiography; Cholesterol; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Intestine, Small; Liver; Male; Mitochondria, Liver; Pregnenolone; Progesterone; Rana esculenta; Sex Factors | 2001 |
Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Blood Glucose; Body Constitution; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Homocysteine; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Metformin; Polycystic Ovary Syndrome; Pregnanolone; Steroids | 2002 |
Serum concentrations of delta 5-3 beta-hydroxysteroids in type 2 diabetes mellitus.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenediol; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Pregnenolone; Statistics, Nonparametric | 2002 |
Serum levels of pregnenolone and 17-hydroxypregnenolone in patients with rheumatoid arthritis and systemic lupus erythematosus: relation to other adrenal hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adult; Aged; Androstenedione; Arthritis, Rheumatoid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Lupus Erythematosus, Systemic; Male; Middle Aged; Pregnenolone; Progesterone | 2003 |
The conversion in vivo of 17-alpha-hydroxypregnenolone to dehydroisoandrosterone and other 17-ketosteroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Biological Assay; Dehydroepiandrosterone; Humans; Lipid Metabolism; Pregnenolone | 1960 |
Effect of dehydroisoandrosterone on the in vivo conversion of 17Alpha-hydroxypregnenolone to urinary 11-desoxy-17-ketosteroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Dehydroepiandrosterone; Humans; Pregnenolone | 1963 |
EVIDENCE THAT STEROID SULFATES SERVE AS BIOSYNTHETIC INTERMEDIATES. II. IN VITRO CONVERSION OF PREGNENOLONE-3H SULFATE-35S TO 17ALPHA-HYDROXYPREGNENOLONE-3H SULFATE-35S.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Cushing Syndrome; Dehydroepiandrosterone; Humans; In Vitro Techniques; Infrared Rays; Metabolism; Pregnanediol; Pregnenolone; Sulfates; Sulfur Isotopes; Tritium; Urine | 1964 |
EFFECT OF ANDROGENS ON STEROID C-21 HYDROXYLATION.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Androgens; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; Hydrocortisone; Hydroxylation; Hydroxyprogesterones; Metabolism; Metyrapone; Microsomes; Mixed Function Oxygenases; Naphthalenes; Pharmacology; Pregnenolone; Progesterone; Pyridines; Research; Steroids; Testosterone | 1964 |
SYNTHESIS OF PREGNENOLONE SULFATE, DEHYDROISOANDROSTERONE SULFATE, 17-ALPHA-HYDROXYPREGNENOLONE SULFATE AND DELTA-5-PREGNENETRIOL SULFATE BY THE NORMAL HUMAN ADRENAL GLAND.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Crystallization; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Metabolism; Pregnanediol; Pregnanetriol; Pregnenes; Pregnenolone; Sulfates; Tritium | 1965 |
SYNTHESIS OF STEROIDS IN THE NEWBORN HUMAN ADRENAL IN VITRO.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Aging; Carbon Isotopes; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydrocortisone; In Vitro Techniques; Infant, Newborn; Metabolism; NADP; Pregnenolone; Progesterone; Radiometry; Steroids | 1965 |
ANDROGEN SYNTHESIS BY TESTICULAR TISSUE FROM A PATIENT WITH GONADAL INSUFFICIENCY.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Androgens; Biopsy; Chromatography; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Hypogonadism; Leydig Cells; Male; Metabolism; Pathology; Pregnenolone; Sertoli Cells; Spermatozoa; Testis; Testosterone; Tritium | 1965 |
STEROID TRANSFORMATIONS IN VITRO BY TESTICULAR TISSUE FROM TWO CASES OF TESTICULAR FEMINISATION.
Topics: 17-alpha-Hydroxypregnenolone; Androgen-Insensitivity Syndrome; Androgens; Chromatography; Cryptorchidism; Dehydroepiandrosterone; Disorders of Sex Development; Humans; In Vitro Techniques; Male; Metabolism; Pregnenolone; Progesterone; Steroids; Testicular Neoplasms; Testis; Testosterone | 1965 |
[INFECTION AND STEROIDS. IN VITRO BIOSYNTHESIS AND CONJUGATION OF STEROIDS IN INFECTION].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Dehydroepiandrosterone; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Pregnenolone; Research; Salmonella Infections; Salmonella Infections, Animal; Steroids | 1965 |
METABOLISM OF PREGNENOLONE-3-SULPHATE IN THE PERFUSED DOG LIVER.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Chromatography; Dehydroepiandrosterone; Dogs; Liver; Perfusion; Pregnenolone; Progesterone; Research; Sulfates; Testosterone | 1965 |
Glucose action and adrenocortical biosynthesis in women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Cohort Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Glucose; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin Resistance; Polycystic Ovary Syndrome; Prospective Studies; Testosterone | 2004 |
Deletion of the mouse P450c17 gene causes early embryonic lethality.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Brain; Dehydroepiandrosterone; Embryonic and Fetal Development; Female; Fetal Death; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Targeting; Mice; Mice, Knockout; Phenotype; Pregnancy; Steroid 17-alpha-Hydroxylase | 2004 |
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds | 2004 |
Refining hormonal diagnosis of type II 3beta-hydroxysteroid dehydrogenase deficiency in patients with premature pubarche and hirsutism based on HSD3B2 genotyping.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Female; Genetic Testing; Genotype; Hirsutism; Humans; Hydrocortisone; Infant; Male; Point Mutation; Predictive Value of Tests; Puberty, Precocious | 2005 |
Cortisol, aldosterone, cortisol precursor, androgen and endogenous ACTH concentrations in dogs with pituitary-dependant hyperadrenocorticism treated with trilostane.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; Animals; Cortodoxone; Dehydroepiandrosterone; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Hydrocortisone; Male; Prospective Studies; Statistics, Nonparametric | 2006 |
Circulating neuroactive C21- and C19-steroids in young men before and after ejaculation.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Ejaculation; Gas Chromatography-Mass Spectrometry; Humans; Male; Orgasm; Pregnanolone; Testosterone | 2006 |
Developmental changes of serum steroids produced by cytochrome P450c17 in rat.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Age Factors; Androstenedione; Animals; Dehydroepiandrosterone; Duodenum; Female; Liver; Male; Rats; Rats, Wistar; Regression Analysis; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Steroids; Testis | 2006 |
Hyperglycaemia acutely decreases circulating dehydroepiandrosterone levels in healthy men.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Analysis of Variance; Androgens; Blood Glucose; Body Composition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Statistics, Nonparametric | 2006 |
Structure-activity relationships of a series of analogs of the endozepine octadecaneuropeptide (ODN(11)(-)(18)) on neurosteroid biosynthesis by hypothalamic explants.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Animals; Dehydroepiandrosterone; Diazepam Binding Inhibitor; Enzyme Activation; Hypothalamus; In Vitro Techniques; Male; Neuropeptides; Peptide Fragments; Peptides, Cyclic; Progesterone; Rana esculenta; Steroid 17-alpha-Hydroxylase; Steroids; Structure-Activity Relationship | 2007 |
The role of porcine cytochrome b5A and cytochrome b5B in the regulation of cytochrome P45017A1 activities.
Topics: 17-alpha-Hydroxypregnenolone; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cell Line; Cloning, Molecular; Cytochromes b5; Dehydroepiandrosterone; Humans; Molecular Sequence Data; Oxidoreductases; Protein Isoforms; Steroid 17-alpha-Hydroxylase; Sus scrofa | 2009 |
Hypocortisolism in the South African angora goat: the role of 3betaHSD.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal Insufficiency; Androstenedione; Animals; Chlorocebus aethiops; COS Cells; Dehydroepiandrosterone; Goat Diseases; Goats; Hydrocortisone; Isoenzymes; Sheep; South Africa; Steroid 17-alpha-Hydroxylase | 2010 |
Clinicopathological features, biochemical and molecular markers in 5 patients with adrenocortical carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Cortodoxone; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Humans; Immunohistochemistry; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm | 2011 |
Differences in stimulated androgen levels in black and white obese adolescent females.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Androgens; Androstenedione; Black or African American; Child; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Humans; Obesity; Pennsylvania; Pilot Projects; Testosterone; White People | 2012 |
Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androstenedione; Biocatalysis; Biosynthetic Pathways; Carbon-Carbon Lyases; Dehydroepiandrosterone; Humans; Hydrogen Bonding; Hydroxylation; Oxidation-Reduction; Spectrum Analysis, Raman; Steroid 17-alpha-Hydroxylase; Substrate Specificity | 2013 |
Adrenal enzyme impairment in neonates and adolescents treated with ritonavir and protease inhibitors for HIV exposure or infection.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Anti-HIV Agents; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; HIV Infections; Humans; Hydrocortisone; Infant, Newborn; Male; Protease Inhibitors; Ritonavir; Young Adult | 2014 |
The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Animals; Anti-Anxiety Agents; Bicuculline; Complex Mixtures; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Gene Expression; Hypothalamus; Isoquinolines; Male; Neuropeptides; Oxazines; Peptide Fragments; Pregnanolone; Progesterone; Rana esculenta; Receptors, GABA-A; Tissue Culture Techniques | 2015 |
Unveiling the crucial intermediates in androgen production.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Biocatalysis; Biosynthetic Pathways; Dehydroepiandrosterone; Humans; Hydrogen Bonding; Hydroxylation; Models, Chemical; Models, Molecular; Molecular Structure; Pregnenolone; Protein Conformation; Spectrophotometry; Steroid 17-alpha-Hydroxylase; Substrate Specificity; Temperature | 2015 |
Distribution and localization of 3β-hydroxysteroid dehydrogenase (3β-HSD) in the brain and its regions of the catfish Heteropneustes fossilis.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 17-Hydroxysteroid Dehydrogenases; Animals; Brain; Catfishes; Dehydroepiandrosterone; Female; Gene Expression Regulation, Enzymologic; Gonads; Male; Pituitary Gland; Reproduction; Seasons; Sex Characteristics; Steroids; Tissue Distribution | 2017 |
Cortisol precursors in neonates with vasopressor-resistant hypotension in relationship to demographic characteristics.
Topics: 17-alpha-Hydroxypregnenolone; Cohort Studies; Dehydroepiandrosterone; Drug Resistance; Female; Gestational Age; Humans; Hydrocortisone; Hypotension; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pregnenolone; Risk Factors; Treatment Failure; Vasoconstrictor Agents | 2018 |
Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Amino Acid Sequence; Amino Acid Substitution; Androstenedione; Animals; Catalysis; Catalytic Domain; Conserved Sequence; Dehydroepiandrosterone; Genes, Synthetic; Humans; Hydrogen Bonding; Mammals; Models, Molecular; Mutation, Missense; Point Mutation; Protein Binding; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Steroid 17-alpha-Hydroxylase; Substrate Specificity | 2018 |
Characterizing the steroidal milieu in amniotic fluid of mid-gestation: A LC-MS/MS study.
Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androsterone; Chromatography, Liquid; Dehydroepiandrosterone; Epitestosterone; Estriol; Estrone; Female; Gestational Age; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Steroids; Tandem Mass Spectrometry | 2019 |
Microcystins and Microcystis aeruginosa PCC7806 extracts modulate steroidogenesis differentially in the human H295R adrenal model.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Cell Line, Tumor; Cytochrome P450 Family 11; Cytochrome P450 Family 21; Dehydroepiandrosterone; Enzyme Inhibitors; Humans; Microcystins; Microcystis | 2020 |
Follicle isolation methods reveal plasticity of granulosa cell steroidogenic capacity during mouse in vitro follicle growth.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alginates; Alkaline Phosphatase; Androgens; Androstenedione; Animals; Carrier Proteins; Dehydroepiandrosterone; Estradiol; Female; Granulosa Cells; Humans; Inhibins; Lyases; Mice; Pregnenolone; Progesterone; Theca Cells | 2022 |