Page last updated: 2024-08-26

17-alpha-hydroxypregnenolone and androsterone

17-alpha-hydroxypregnenolone has been researched along with androsterone in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199018 (62.07)18.7374
1990's5 (17.24)18.2507
2000's3 (10.34)29.6817
2010's2 (6.90)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Chapman, D; Jain, AN; Koile, K1
Good, AC; Richards, WG; So, SS1
Platt, DE; Silverman, BD1
Crippen, GM1
Karplus, M; So, SS1
Strassburg, CP; Tukey, RH1
Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N1
Bellavance, E; Luu-The, V; Poirier, D1
Bertamino, R; Crovato, F; Moretti, G1
Belvedere, PC; Colombo, L1
Kannari, K; Kimura, K; Takebe, K; Watanobe, H1
Vihko, R1
Bandi, L; Calvin, HI; Cos, JJ; Lieberman, S; Roberts, KD; Weiss, C1
Christie, GA1
Bulbrook, RD; Carson, P; Deshpande, N; Doouss, TW; Jensen, V1
Francis, FE; Kinsella, RA1
Bicknell, DC; Gower, DB1
Laatikainen, T; Laitinen, EA; Ruokonen, A; Vihko, R1
Huhtaniemi, I; Vihko, R1
Hipkin, LJ1
Laatikainen, TJ; Nylander, PL; Peltonen, JI1
Bardin, CW; Kirschner, MA; Lipsett, MB; Wilson, H1
Gregorová, I; Horký, K; Kuchel, O; Stárka, L1
Idler, DR; O'Halloran, MJ1
Meyer, RK; Ying, SY1
Dutter, F; Jayle, MF; Pasqualini, JR1
Arlt, W; Hughes, BA; Jones, CM; Krone, N; Mallappa, A; Merke, DP; Nikolaou, N; O'Neil, DM; Reisch, N; Ross, RJ; Storbeck, KH; Tomlinson, JW; Whitaker, MJ1
Hartmann, MF; Sánchez-Guijo, A; Tiosano, D; Wang, R; Wudy, SA1
Akıncı, E; Bal, C; Erel, Ö; Eser, F; Güner, R; Hasanoglu, İ; Kalem, AK; Kayaaslan, B; Sezer, S; Yılmaz, G1

Reviews

1 review(s) available for 17-alpha-hydroxypregnenolone and androsterone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Trials

1 trial(s) available for 17-alpha-hydroxypregnenolone and androsterone

ArticleYear
Effect of aminoglutethimide on urinary steroid excretion in patients with congenital adrenal hyperplasia due to incomplete 21-hydroxylase deficiency.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Androsterone; Aniline Compounds; Anticonvulsants; Chemistry, Clinical; Clinical Trials as Topic; Dehydroepiandrosterone; Depression, Chemical; Dexamethasone; Etiocholanolone; Female; Humans; Metabolism, Inborn Errors; Metyrapone; Mixed Function Oxygenases; Pregnanetriol; Pyridones

1972

Other Studies

27 other study(ies) available for 17-alpha-hydroxypregnenolone and androsterone

ArticleYear
Compass: predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: Algorithms; Models, Molecular; Models, Statistical; Molecular Conformation; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Surface Properties; Transcortin

1994
Structure-activity relationships from molecular similarity matrices.
    Journal of medicinal chemistry, 1993, Feb-19, Volume: 36, Issue:4

    Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin

1993
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
    Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11

    Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone

1996
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.
    Journal of medicinal chemistry, 1997, Sep-26, Volume: 40, Issue:20

    Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin

1997
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 1. Method and validations.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Algorithms; Models, Chemical; Molecular Structure; Neural Networks, Computer; Protein Binding; Static Electricity; Steroids; Structure-Activity Relationship; Transcortin

1997
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids

2008
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.
    Archiv fur dermatologische Forschung, 1975, Volume: 251, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Cytoplasm; Cytoplasmic Granules; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Hair; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Rats; Sebaceous Glands; Skin; Testosterone

1975
Steroid biosynthesis by the ovary of the European eel, Anguilla anguilla L., at the silver stage.
    General and comparative endocrinology, 1976, Volume: 28, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androstenedione; Androsterone; Animals; Dehydroepiandrosterone; Eels; Female; Hydroxyprogesterones; Kinetics; Metyrapone; Ovary; Pregnenes; Pregnenolone; Progesterone; Testosterone

1976
Adrenocortical carcinoma with Cushing's syndrome presenting unusual urinary 17-ketosteroid fractionation.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adult; Androstenedione; Androsterone; Cortodoxone; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Etiocholanolone; Humans; Male; Tomography, X-Ray Computed

1985
Gas chromatographic-mass spectrometric studies on solvolyzable steroids in human peripheral plasma.
    Acta endocrinologica, 1966, Volume: 52

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androsterone; Bile Acids and Salts; Blood Chemical Analysis; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Etiocholanolone; Humans; In Vitro Techniques; Pregnenolone; Progesterone; Spectrum Analysis; Steroids; Testosterone

1966
Column liquid-liquid partition chromatography of steroidal sulfates.
    Analytical biochemistry, 1966, Volume: 15, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Cholesterol; Chromatography; Dehydroepiandrosterone; Etiocholanolone; Pregnanediol; Pregnenolone; Steroids; Sterols; Sulfates

1966
Distribution of hydroxysteroid dehydrogenases in the placenta of the pig.
    The Journal of endocrinology, 1968, Volume: 40, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Castration; Dehydroepiandrosterone; Epithelium; Estradiol; Estrogens; Etiocholanolone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Ovary; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Swine; Trophoblasts

1968
Adrenal function in breast cancer: biogenesis of androgens and cortisol by the human adrenal gland in vivo.
    The Journal of endocrinology, 1970, Volume: 47, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aged; Androgens; Androstanes; Androsterone; Breast Neoplasms; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovary; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium

1970
Steroids and sterols in meconium.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 32, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Androsterone; Bile; Chromatography; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Fetus; Glucuronates; Humans; Infant, Newborn; Intestine, Small; Maternal-Fetal Exchange; Meconium; Placenta; Pregnancy; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sterols; Testosterone

1971
The separation of C19-16-unsaturated steroids from C21 and other C19-steroids by two-dimensional thin-layer chromatography.
    Journal of chromatography, 1971, Volume: 61, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstanes; Androsterone; Autoradiography; Chromatography, Thin Layer; Dehydroepiandrosterone; Estrogens; Etiocholanolone; Hydroxyprogesterones; Methods; Pregnenolone; Progestins; Testosterone

1971
Free and sulfate-conjugated neutral steroids in human testis tissue.
    Biochemistry, 1972, Apr-11, Volume: 11, Issue:8

    Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Aged; Androstanes; Androsterone; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Humans; Hydroxysteroids; Ketosteroids; Male; Mass Spectrometry; Middle Aged; Pregnanediol; Pregnanes; Pregnenolone; Steroids; Sulfuric Acids; Testis; Testosterone

1972
Steroid metabolism in kidney tissue. I. Endogenous neutral steroids in foetal kidneys and studies on their formation.
    Acta endocrinologica, 1972, Volume: 71, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Buffers; Chromatography; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydroxyprogesterones; In Vitro Techniques; Kidney; Mass Spectrometry; Methods; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfates; Sulfurtransferases; Time Factors

1972
Augmentation of the rat uterine weight response to human chorionic gonadotrophin by various steroids.
    Acta endocrinologica, 1974, Volume: 75, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Androsterone; Animals; Body Weight; Castration; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Organ Size; Ovary; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Testosterone; Uterus

1974
Effect of maternal intrahepatic cholestasis on fetal steroid metabolism.
    The Journal of clinical investigation, 1974, Volume: 53, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Androsterone; Birth Weight; Cholestasis; Dehydroepiandrosterone; Estriol; Female; Fetus; Gestational Age; Humans; Hydroxylation; Male; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications; Pregnanediol; Pregnanetriol; Pregnenolone; Progesterone; Steroids; Umbilical Cord

1974
Malignant lipid cell tumor of the ovary: clinical, biochemical and etiologic considerations.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adult; Androstanes; Androsterone; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Etiocholanolone; Female; Glucuronates; Humans; Hydroxyprogesterones; Neoplasm Metastasis; Ovarian Neoplasms; Pregnanes; Pregnanetriol; Sertoli-Leydig Cell Tumor; Sulfates; Testosterone; Virilism

1970
Identification and distribution of the Leydig cell homolog in the testis of sexually mature Atlantic salmon (Salmo salar).
    General and comparative endocrinology, 1970, Volume: 15, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androsterone; Animals; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Pregnenolone; Salmonidae

1970
Effect of steroids on neuropharmacologic blockade of ovulation in pregnant mare's serum (PMS)-primed immature rats.
    Endocrinology, 1969, Volume: 84, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androsterone; Animals; Depression, Chemical; Desoxycorticosterone; Estradiol; Estrone; Female; Gonadotropins, Equine; Hydrocortisone; Hydroxyprogesterones; Luteinizing Hormone; Medroxyprogesterone; Organ Size; Ovulation; Phenobarbital; Progesterone; Rats

1969
The metabolism of 3-beta,21-dihydroxypregn-5-en-20-one and 3-beta,17-alpha,21-trihydroxypregn-5-en-20-one in man.
    The Journal of endocrinology, 1966, Volume: 35, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Androsterone; Chromatography, Paper; Etiocholanolone; Female; Glucuronates; Humans; Hydroxyprogesterones; In Vitro Techniques; Male

1966
Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Androgens; Androsterone; Circadian Rhythm; Cortodoxone; Delayed-Action Preparations; Dexamethasone; Female; Gas Chromatography-Mass Spectrometry; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Prednisolone; Pregnanetriol; Young Adult

2017
Characterizing the steroidal milieu in amniotic fluid of mid-gestation: A LC-MS/MS study.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 185

    Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androsterone; Chromatography, Liquid; Dehydroepiandrosterone; Epitestosterone; Estriol; Estrone; Female; Gestational Age; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Steroids; Tandem Mass Spectrometry

2019
COVID-19 patients with altered steroid hormone levels are more likely to have higher disease severity.
    Endocrine, 2022, Volume: 78, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldosterone; Androstenedione; Androsterone; Chromatography, Liquid; Corticosterone; Cortodoxone; COVID-19; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Estradiol; Estrone; Humans; Hydrocortisone; Pregnenolone; Progesterone; Severity of Illness Index; Tandem Mass Spectrometry

2022