Page last updated: 2024-08-26

17-alpha-hydroxypregnenolone and aldosterone

17-alpha-hydroxypregnenolone has been researched along with aldosterone in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's3 (16.67)18.2507
2000's4 (22.22)29.6817
2010's0 (0.00)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Platt, DE; Silverman, BD1
Strassburg, CP; Tukey, RH1
Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N1
Bellavance, E; Luu-The, V; Poirier, D1
Bongiovanni, AM; Genel, M; Goldman, AS; Rosenfield, RL; Schneider, G1
Genest, J; Kuchel, O; Nowaczynksi, W; Richardson, K1
Itakura, M; Koide, Y; Kuzuya, N; Matsumara, M; Murayama, Y; Nakamura, S; Okuda, Y; Takuwa, Y; Tomizawa, H; Watanabe, Y1
Berg, GJ; Lee, MM; Moshang, T; Rajagopalan, L1
Claus, M; Schöneshöfer, M1
Goshima, E; Hirai, M; Miura, K; Murase, H; Murayama, M; Noritake, N; Takeda, N; Yamakita, N; Yasuda, K1
Schuetz, AW1
Wolff, HP1
Blank, IH; Brauner, GJ; MacFarlane, DJ; Scheuplein, RJ1
Goncharov, NP; Taranov, AG1
Goncharov, NP; Tavadian, DS1
Altare, S; Canivet, B; Hadjali, Y; Kézachian, B; Sadoul, JL1
Boretti, FS; Maser-Gluth, C; Reusch, CE; Sieber-Ruckstuhl, NS; Wenger, M1
Akıncı, E; Bal, C; Erel, Ö; Eser, F; Güner, R; Hasanoglu, İ; Kalem, AK; Kayaaslan, B; Sezer, S; Yılmaz, G1

Reviews

2 review(s) available for 17-alpha-hydroxypregnenolone and aldosterone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
[Clinical steroid analysis, using H3 and C14 (determination of their secretion, plasma concentration, secretion rate, as well as metabolism and renal clearance rate)].
    Nuclear-Medizin, 1965

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Aldosterone; Carbon Isotopes; Chemistry, Clinical; Dehydroepiandrosterone; Heart Failure; Humans; Hydrocortisone; Hypertension, Renal; Kidney; Liver Cirrhosis; Nephrotic Syndrome; Radioisotope Dilution Technique; Secretory Rate; Steroids; Tritium

1965

Other Studies

16 other study(ies) available for 17-alpha-hydroxypregnenolone and aldosterone

ArticleYear
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
    Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11

    Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone

1996
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids

2008
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Persistent testicular delta5-isomerase-3beta-hydroxysteroid dehydrogenase (delta5-3beta-HSD) deficiency in the delta5-3beta-HSD form of congenital adrenal hyperplasia.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Chorionic Gonadotropin; Dexamethasone; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Isomerases; Male; Pregnanetriol; Puberty; Sodium; Testis; Testosterone

1975
[Do aldosterone and other mineralocorticoids play a role in the pathogenesis of essential hypertension?].
    L'union medicale du Canada, 1977, Volume: 106, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Proteins; Circadian Rhythm; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxylation; Hypertension; Liver; Liver Circulation; Metabolic Clearance Rate; Mineralocorticoids; Mixed Function Oxygenases; Posture; Progesterone; Protein Binding

1977
Successful treatment of a metastatic hormone-producing adrenal cancer by a combination of mitotane, tegafur and surgical resection.
    Endocrinologia japonica, 1990, Volume: 37, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Gland Neoplasms; Adult; Aldosterone; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Corticosterone; Heart Neoplasms; Humans; Hydrocortisone; Liver Neoplasms; Lung Neoplasms; Male; Mitotane; Pregnenolone; Tegafur; Testosterone

1990
Serum adrenal steroid concentrations in premature infants.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; Aldosterone; Androstenedione; Birth Weight; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Gestational Age; Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Infant, Newborn; Infant, Premature; Male; Steroids

1989
Multiple-sites of inhibition by intravenous metyrapone of human adrenal steroidogenesis.
    Acta endocrinologica, 1985, Volume: 109, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Corticosterone; Cortodoxone; Humans; Hydrocortisone; Hydroxyprogesterones; Infusions, Parenteral; Male; Metyrapone; Pregnenolone; Progesterone

1985
Response of plasma adrenal steroids to synthetic ACTH under ketoconazole in man.
    Endocrinologia japonica, 1987, Volume: 34, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldehyde-Lyases; Aldosterone; Corticosterone; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase

1987
Effect of steroids on germinal vesicle of oocytes of the frog (Rana pipiens) in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Aldosterone; Androgens; Animals; Anura; Cell Nucleus; Cholesterol; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Hydrocortisone; In Vitro Techniques; Ovum; Pregnanediol; Pregnenolone; Progesterone; Steroids; Testosterone

1967
Percutaneous absorption of steroids.
    The Journal of investigative dermatology, 1969, Volume: 52, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; Administration, Topical; Aldosterone; Anti-Inflammatory Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Corticosterone; Cortisone; Desoxycorticosterone; Diffusion; Estradiol; Estriol; Estrone; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Skin Absorption; Steroids; Testosterone

1969
[Characteristics of the relationship between the circadian rhythm of the concentrations of corticosteroids and their precursors in the blood of baboon hamadryas and the initial functional state of the pituitary-adrenal cortex system].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Aldosterone; Animals; Circadian Rhythm; Cortodoxone; Hydrocortisone; Hydroxyprogesterones; Male; Papio; Pituitary-Adrenal System; Pregnenolone; Progesterone

1981
[Dynamics of the concentration of aldosterone, cortisol, and its precursors in the plasma of M. rhesus during long-term restriction of motor activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 90, Issue:12

    Topics: 17-alpha-Hydroxypregnenolone; Adaptation, Physiological; Adrenal Glands; Aldosterone; Animals; Cortodoxone; Hydrocortisone; Hydroxyprogesterones; Macaca mulatta; Male; Movement; Stress, Physiological

1980
Apparent activities of 21-hydroxylase, 17alpha-hydroxylase and 17,20-lyase are impaired in adrenal incidentalomas.
    European journal of endocrinology, 1999, Volume: 141, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Aldosterone; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Progesterone; Prospective Studies; Renin; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase

1999
Cortisol, aldosterone, cortisol precursor, androgen and endogenous ACTH concentrations in dogs with pituitary-dependant hyperadrenocorticism treated with trilostane.
    Domestic animal endocrinology, 2006, Volume: 31, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; Animals; Cortodoxone; Dehydroepiandrosterone; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Hydrocortisone; Male; Prospective Studies; Statistics, Nonparametric

2006
COVID-19 patients with altered steroid hormone levels are more likely to have higher disease severity.
    Endocrine, 2022, Volume: 78, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldosterone; Androstenedione; Androsterone; Chromatography, Liquid; Corticosterone; Cortodoxone; COVID-19; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Estradiol; Estrone; Humans; Hydrocortisone; Pregnenolone; Progesterone; Severity of Illness Index; Tandem Mass Spectrometry

2022