16-hydroxyandrost-4-en-3,17-dione has been researched along with androstenedione in 19 studies
| Studies (16-hydroxyandrost-4-en-3,17-dione) | Trials (16-hydroxyandrost-4-en-3,17-dione) | Recent Studies (post-2010) (16-hydroxyandrost-4-en-3,17-dione) | Studies (androstenedione) | Trials (androstenedione) | Recent Studies (post-2010) (androstenedione) |
|---|---|---|---|---|---|
| 20 | 0 | 1 | 7,175 | 377 | 960 |
| Protein | Taxonomy | 16-hydroxyandrost-4-en-3,17-dione (IC50) | androstenedione (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 1.55 | |
| Aromatase | Homo sapiens (human) | 0.3 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.6761 | |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | 0.6826 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Numazawa, M; Osawa, Y | 1 |
| Mutsumi, A; Nagaoka, M; Nakakoshi, M; Numazawa, M | 1 |
| Furihata, R; Ishikawa, S; Konno, T; Numazawa, M | 1 |
| Oakey, RE; Purohit, A | 1 |
| Franks, S; Polson, DW; Quiney, N; Reed, MJ; Scanlon, MJ | 1 |
| Numazawa, M; Osawa, Y; Tsuji, M; Yarborough, C | 1 |
| Numazawa, M; Osada, R; Osawa, Y; Tsuji, M | 1 |
| Arai, K; Dobashi, K; Ikegawa, A; Kambegawa, A; Ohkawa, T; Okinaga, S; Sano, Y | 1 |
| Ikegawa, A | 1 |
| Biener, A; Bulletti, C; Guller, S; Gurpide, E | 1 |
| Mutsumi, A; Numazawa, M | 1 |
| Oakey, RE; Othman, YS | 1 |
| Numazawa, M; Yoshimura, A | 1 |
| Nagaoka, M; Numazawa, M; Yoshimura, A | 1 |
| Mutsumi, A; Numazawa, M; Osawa, Y; Tachibana, M; Yoshimura, A | 1 |
| Matsuzaki, H; Numazawa, M; Watari, Y; Yoshimura, A | 1 |
| Mutsumi, A; Numazawa, M; Tachibana, M; Yoshimura, A | 1 |
| Komatsu, S; Nagaoka, M; Numazawa, M; Watari, Y; Yamashita, K | 1 |
| Bernhardt, R; Hartmann, MF; Khatri, Y; Milhim, M; Neunzig, J; Sánchez-Guijo, A; Schiffer, L; Wudy, SA; Zapp, J | 1 |
19 other study(ies) available for 16-hydroxyandrost-4-en-3,17-dione and androstenedione
| Article | Year |
|---|---|
Improved synthesis of 16alpha-hydroxylated androgens: intermediates of estriol formation in pregnancy.
Topics: Androgens; Androstenedione; Animals; Dehydroepiandrosterone; Estriol; Female; Hydroxytestosterones; Magnetic Resonance Spectroscopy; Methods; Oxidation-Reduction; Pregnancy; Spectrophotometry, Infrared | 1978 |
A radiometric assay method for aromatase activity using [1 beta-3H]16 alpha-hydroxyandrostenedione.
Topics: Androstenedione; Aromatase; Female; Humans; In Vitro Techniques; Isotope Labeling; Microsomes; Placenta; Pregnancy; Streptomyces | 1992 |
Determination of aromatization of 19-oxygenated 16 alpha-hydroxyandrostenedione with human placental microsomes by high-performance liquid chromatography coupled with coulometric detection.
Topics: Androstenedione; Aromatase; Chromatography, High Pressure Liquid; Estriol; Female; Humans; Hydroxyestrones; Kinetics; Microsomes; Placenta; Substrate Specificity | 1990 |
Evidence for separate sites for aromatisation of androstenedione and 16 alpha-hydroxyandrostenedione in human placental microsomes.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Estradiol; Estriol; Estrone; Female; Humans; Hydroxyestrones; In Vitro Techniques; Kinetics; Microsomes; Placenta; Pregnancy; Radioimmunoassay | 1989 |
Androstenedione concentrations following dexamethasone suppression: correlation with clomiphene responsiveness in women with polycystic ovary syndrome.
Topics: Amenorrhea; Androstenedione; Clomiphene; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Luteinizing Hormone; Polycystic Ovary Syndrome; Reference Values; Testosterone | 1988 |
Preparation of [1,2-3H,4-14C]16 alpha-hydroxyandrostenedione and its use for radiometric determination of human placental aromatase activity.
Topics: Androstenedione; Aromatase; Female; Humans; In Vitro Techniques; Microsomes; Placenta; Pregnancy | 1987 |
High-performance liquid chromatographic determination of aromatization of 16 alpha-hydroxylated androgens with human placental microsomes.
Topics: Androgens; Androstenedione; Chromatography, Gel; Chromatography, High Pressure Liquid; Estriol; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Hydroxytestosterones; In Vitro Techniques; Kinetics; Microchemistry; Microsomes; Placenta | 1985 |
A new radioimmunoassay for serum 16 alpha-hydroxyandrost-4-ene-3,17-dione with specific antiserum.
Topics: Amniotic Fluid; Androstenedione; Antibody Specificity; Female; Humans; Immune Sera; Microchemistry; Pregnancy; Radioimmunoassay; Reference Values; Umbilical Arteries | 1985 |
[Studies on 16 alpha-hydroxyandrost-4-ene-3, 17-dione in human pregnancy measured by high performance liquid chromatography and radioimmunoassay].
Topics: Androstenedione; Chromatography, High Pressure Liquid; Female; Fetal Blood; Humans; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Radioimmunoassay; Umbilical Arteries; Umbilical Veins | 1985 |
Relative distribution of estrone, estradiol and estriol between fetal and maternal perfusates during perfusions of human term placentas with labelled C19 precursors.
Topics: Androstenedione; Estradiol; Estriol; Estrone; Ethinyl Estradiol; Female; Humans; In Vitro Techniques; Perfusion; Placenta; Pregnancy; Time Factors; Tissue Distribution | 1984 |
Inhibition study of human placental aromatase with 3-deoxy- and 6-oxo-steroids using [1 beta-3H]16 alpha-hydroxyandrostenedione as a substrate: a comparison to that using [1 beta-3H]androstenedione.
Topics: Androstenedione; Aromatase Inhibitors; Humans; Placenta; Steroids; Substrate Specificity | 1993 |
Why so much oestriol? A comparison of the aromatisation of androstenedione and 16 alpha-hydroxyandrostenedione when incubated alone or together with human placental microsomes.
Topics: Androstenedione; Aromatase; Estradiol; Estriol; Humans; In Vitro Techniques; Microsomes; Placenta; Radioimmunoassay | 1996 |
Synthesis of 19-oxygenated 4beta,5beta-epoxy derivatives of 16alpha-hydroxyandrostenedione as mechanistic and catalytic probes for aromatase reaction.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Catalysis; Epoxy Compounds; Indicators and Reagents; Thermodynamics | 2000 |
Gas chromatography-mass spectrometric determination of activity of human placental aromatase using 16alpha-hydroxyandrostenedione as a substrate.
Topics: Androstenedione; Aromatase; Female; Gas Chromatography-Mass Spectrometry; Humans; Placenta | 2001 |
Aromatization of 16alpha-hydroxyandrostenedione by human placental microsomes: effect of preincubation with suicide substrates of androstenedione aromatization.
Topics: Androstenedione; Aromatase; Female; Humans; Microsomes; Placenta; Pregnancy | 2002 |
Aromatase inhibition by 4 beta,5 beta-epoxides of 16 alpha-hydroxyandrostenedione and its 19-oxygenated analogs, potential precursors of estriol production in the feto-placental unit.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Enzyme Inhibitors; Epoxy Compounds; Estriol; Fetus; Humans; Placenta | 2002 |
Kinetic analysis of reversible inhibition of 16alpha-hydroxyandrostenedione aromatization in human placental microsomes by suicide substrates of androstenedione aromatization.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Catalysis; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Microsomes; Placenta; Substrate Specificity | 2003 |
Aromatization of androstenedione and 16alpha-hydroxyandrostenedione in human placental microsomes. Kinetic analysis of inhibition by the 19-oxygenated and 3-deoxy analogs.
Topics: Androstenedione; Aromatase Inhibitors; Cyclization; Female; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microsomes; Oxygen; Placenta; Spectroscopy, Fourier Transform Infrared | 2008 |
The steroid metabolite 16(β)-OH-androstenedione generated by CYP21A2 serves as a substrate for CYP19A1.
Topics: Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Catalysis; Child, Preschool; Crystallography, X-Ray; Dose-Response Relationship, Drug; Endocrine System; Endocrine System Diseases; Escherichia coli; Estrogen Receptor alpha; Female; Humans; Kinetics; Magnetic Resonance Spectroscopy; Receptors, Androgen; Recombinant Proteins; Spectrophotometry, Ultraviolet; Steroid 21-Hydroxylase; Steroids | 2017 |