Page last updated: 2024-08-25

16-bromoepiandrosterone and androsterone

16-bromoepiandrosterone has been researched along with androsterone in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's1 (6.67)18.2507
2000's7 (46.67)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dawson, M; Fairweather, EE; Hamilton, NM; Hamilton, NS; Hitchin, JR; James, DI; Jones, SD; Jordan, AM; Lyons, AJ; Ogilvie, DJ; Small, HF; Thomson, GJ; Waddell, ID1
Destiche, DA; Frincke, JM; Garsd, A; Noveljic, Z; Stickney, DR1
Auci, DL; Conrad, D; Frincke, J; Mangano, K; Nicoletti, F; Pieters, R; Reading, CL; Stickney, D; van Heeckeren, A; Wang, A; White, SK1
Gordon, GB; Newitt, JA; Shantz, LM; Talalay, P; Weng, DE1
Schwartz, AG; Whitcomb, JM1
Abou-Gharbia, M; Henderson, E; Pashko, L; Schwartz, A; Swern, D1
Chitano, P; Dashtaki, R; Kennedy, TP; Murphy, TM; Reed, W; Whorton, AR1
Arese, P; Ayi, K; Giribaldi, G; Prendergast, PT; Schwarzer, E; Skorokhod, A1
Henderson, GL; Higgins, J; Leutenegger, C; North, TW; Pedersen, NC; Reading, C; Rigg, R1
Aguilar-Leon, D; Ahlem, C; Frincke, J; Hernández-Pando, R; Orozco, H; Reading, C; Rook, GA; Schramm, B; Serrano, A; Trauger, R1
Dowding, C; Frincke, J; Garsd, A; Onizuka-Handa, N; Reading, C; Schramm, B; Stickney, D1
Frincke, JM; Garsd, A; Krudsood, S; Looareesuwan, S; Onizuka-Handa, N; Reading, C; Stickney, DR; Wilairatana, P1
Carrero, JC; Cervantes-Rebolledo, C; Dowding, C; Frincke, J; Hernández-Bello, R; Morales-Montor, J; Reading, C; Vargas-Villavicencio, JA1
Cordeiro, AT; Thiemann, OH1
Carrero, JC; Cervantes-Rebolledo, C; Dowding, C; Escobedo, G; Frincke, J; Hernández-Bello, R; Morales-Montor, J; Reading, C1

Trials

3 trial(s) available for 16-bromoepiandrosterone and androsterone

ArticleYear
Safety and activity of the immune modulator HE2000 on the incidence of tuberculosis and other opportunistic infections in AIDS patients.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Amylases; Androsterone; CD4 Lymphocyte Count; Diarrhea; Double-Blind Method; Drug Tolerance; Female; Humans; Immunologic Factors; Incidence; Male; Middle Aged; Tuberculosis; Viral Load

2007
Improvement in immune parameters and human immunodeficiency virus-1 viral response in individuals treated with 16alpha-bromoepiandrosterone (HE2000).
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2006, Volume: 12, Issue:11

    Topics: Adult; Androsterone; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Cell Count; Cyclooxygenase 2; Dendritic Cells; Double-Blind Method; Female; Flow Cytometry; HIV Infections; HIV-1; Humans; Injections, Subcutaneous; Interleukin-1; Interleukin-2 Receptor alpha Subunit; Interleukin-6; Killer Cells, Natural; Lectins, C-Type; Leukocyte Count; Leukocytes, Mononuclear; Male; Membrane Proteins; Reagent Kits, Diagnostic; RNA, Messenger; T-Lymphocytes; Treatment Outcome; Tumor Necrosis Factor-alpha; Viral Load

2006
Reduction of parasite levels in patients with uncomplicated malaria by treatment with HE2000.
    The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:2

    Topics: Adult; Androsterone; Animals; Body Temperature; Female; Humans; Immunologic Factors; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Thailand

2007

Other Studies

12 other study(ies) available for 16-bromoepiandrosterone and androsterone

ArticleYear
Novel steroid inhibitors of glucose 6-phosphate dehydrogenase.
    Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9

    Topics: Antineoplastic Agents; Cell Survival; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; HEK293 Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pregnanes; Structure-Activity Relationship

2012
16alpha-Bromoepiandrosterone (HE2000) limits non-productive inflammation and stimulates immunity in lungs.
    Clinical and experimental immunology, 2009, Volume: 158, Issue:3

    Topics: Acute Lung Injury; Androsterone; Animals; Carrageenan; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunity, Innate; Influenza A Virus, H1N1 Subtype; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitric Oxide; Opportunistic Infections; Orthomyxoviridae Infections; Pleurisy; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections

2009
Inhibition of the conversion of 3T3 fibroblast clones to adipocytes by dehydroepiandrosterone and related anticarcinogenic steroids.
    Cancer research, 1986, Volume: 46, Issue:7

    Topics: Adipose Tissue; Androsterone; Animals; Cell Differentiation; Cell Survival; Cytosol; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Administration Schedule; Glucosephosphate Dehydrogenase; Mice; Structure-Activity Relationship

1986
Dehydroepiandrosterone and 16 alpha-Br-epiandrosterone inhibit 12-O-tetradecanoylphorbol-13-acetate stimulation of superoxide radical production by human polymorphonuclear leukocytes.
    Carcinogenesis, 1985, Volume: 6, Issue:3

    Topics: Androsterone; Dehydroepiandrosterone; Free Radicals; Glucosephosphate Dehydrogenase; Humans; In Vitro Techniques; Neutrophils; Phorbols; Superoxides; Tetradecanoylphorbol Acetate

1985
Dehydroepiandrosterone and 16 alpha-bromo-epiandrosterone: inhibitors of Epstein-Barr virus-induced transformation of human lymphocytes.
    Carcinogenesis, 1981, Volume: 2, Issue:7

    Topics: Androsterone; Animals; Cell Line; Cell Transformation, Viral; Dehydroepiandrosterone; DNA; Herpesvirus 4, Human; Humans; Lymphocytes; Mitogens; Rats; Thymidine

1981
Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:2

    Topics: Androsterone; Animals; Cell Division; Cells, Cultured; Dehydroepiandrosterone; DNA; Dose-Response Relationship, Drug; Male; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Trachea; Transcription Factor AP-1

1998
16alpha-bromoepiandrosterone, an antimalarial analogue of the hormone dehydroepiandrosterone, enhances phagocytosis of ring stage parasitized erythrocytes: a novel mechanism for antimalarial activity.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:10

    Topics: Adult; Androsterone; Animals; Antimalarials; Cell Membrane; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Erythrocytes; Female; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Phagocytosis; Phosphatidylserines; Plasmodium falciparum

2002
16alpha-Bromo-epiandrosterone therapy modulates experimental feline immunodeficiency virus viremia: initial enhancement leading to long-term suppression.
    Veterinary immunology and immunopathology, 2003, Aug-15, Volume: 94, Issue:3-4

    Topics: Adjuvants, Immunologic; Androsterone; Animals; Antibodies, Viral; Cats; CD4-CD8 Ratio; Cytokines; Enzyme-Linked Immunosorbent Assay; Feces; Feline Acquired Immunodeficiency Syndrome; Immunodeficiency Virus, Feline; Interferon-gamma; Male; Polymerase Chain Reaction; Random Allocation; RNA, Messenger; Specific Pathogen-Free Organisms; T-Lymphocytes; Viremia

2003
16alpha-Bromoepiandrosterone restores T helper cell type 1 activity and accelerates chemotherapy-induced bacterial clearance in a model of progressive pulmonary tuberculosis.
    The Journal of infectious diseases, 2005, Jan-15, Volume: 191, Issue:2

    Topics: Adjuvants, Immunologic; Androsterone; Animals; Chemotherapy, Adjuvant; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Th1 Cells; Tuberculosis, Pulmonary; Tumor Necrosis Factor-alpha

2005
Parasiticidal effect of 16alpha-bromoepiandrosterone (EpiBr) in amoebiasis and cysticercosis.
    Microbes and infection, 2010, Volume: 12, Issue:8-9

    Topics: Amebiasis; Androsterone; Animals; Anthelmintics; Antiprotozoal Agents; Cell Survival; Cricetinae; Cysticercosis; Entamoeba histolytica; Female; Histocytochemistry; Liver Abscess; Locomotion; Male; Mice; Survival Analysis; Taenia

2010
16-bromoepiandrosterone, an activator of the mammalian immune system, inhibits glucose 6-phosphate dehydrogenase from Trypanosoma cruzi and is toxic to these parasites grown in culture.
    Bioorganic & medicinal chemistry, 2010, Jul-01, Volume: 18, Issue:13

    Topics: Androsterone; Dehydroepiandrosterone; Glucosephosphate Dehydrogenase; Humans; Immune System; Kinetics; Recombinant Proteins; Trypanocidal Agents; Trypanosoma cruzi; Trypanosomiasis, African

2010
A new parasiticidal compound in T. solium cysticercosis.
    BioMed research international, 2013, Volume: 2013

    Topics: Androsterone; Animals; Antiparasitic Agents; Cell Proliferation; Cricetinae; Cysticercosis; Dehydroepiandrosterone; Entamoeba histolytica; Intestines; Male; Mesocricetus; Muscles; Spleen; Swine; Taenia solium

2013