15-keto-13-14-dihydroprostaglandin-f2alpha has been researched along with anandamide* in 1 studies
1 other study(ies) available for 15-keto-13-14-dihydroprostaglandin-f2alpha and anandamide
| Article | Year |
|---|---|
Altered productions of prostaglandins and prostamides by human amnion in response to infectious and inflammatory stimuli identified by mutliplex mass spectrometry.
Prostaglandins are critical for the onset and progression of labor in mammals, and are formed by the metabolism of arachidonic acid. The products of arachidonic acid, 2-arachidonoylglycerol (2-AG), and anandamide (AEA) have a similar lipid back bone but differing polar head groups, meaning that identification of these products by immunoassay can be difficult.. In the current study, we present the use of mass spectrometry as multiplex method of identifying the specific end products of arachidonic and anandamide metabolism by human derived amnion explants treated with either an infectious agent (LPS) or inflammatory mediator (IL-1β or TNF-α).. Human amnion tissue explants treated with LPS, IL-1β, or TNF-α increased production of prostaglandin E Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Cytokines; Dinoprost; Dinoprostone; Endocannabinoids; Female; Humans; Interleukin-1beta; Lipopolysaccharides; Mass Spectrometry; Polyunsaturated Alkamides; Pregnancy; Tumor Necrosis Factor-alpha | 2020 |