15-hydroxy-5,8,11,13,17-eicosapentaenoic acid and eicosapentaenoic acid

15-hydroxy-5,8,11,13,17-eicosapentaenoic acid has been researched along with eicosapentaenoic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's2 (11.11)18.2507
2000's4 (22.22)29.6817
2010's10 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, C; Yamaguchi, RY; Ziboh, VA1
Egsgaard, H; Fogh, K; Kragballe, K; Larsen, E; Shukla, VK1
Fujimoto, Y; Fujita, T; Muta, E; Nishida, H; Sakuma, S; Tsunomori, M1
Fujimoto, Y; Fujita, T; Sakuma, S; Yamamoto, N1
Brannon, J; Chiang, N; Clish, CB; Colgan, SP; Gronert, K; Serhan, CN1
Inoue, H1
Baek, SJ; Bottone, FG; Eling, TE; Kim, JS; Sali, T1
Heard, CM; Thomas, CP1
Hung, ND; Kim, MR; Sok, DE1
Allayee, H; Armstrong, P; Hartiala, J; Kelley, D; Legault, J; Nassir, R; Newman, JW; Pedersen, TL; Schuster, GU; Seldin, MF; Stephensen, CB; Vikman, S1
Chiu, YC; Fu, WM; Lin, TH; Liou, HC; Wu, MY; Yang, RS1
Desbois, AP; Lawlor, KC1
Li, J; Lian, M; Shen, T; Shi, H; Wei, L; Xing, Y; Yu, X; Zhang, B; Zhu, D1
Chattopadhyay, R; Dyukova, E; Kotla, S; Mobley, JA; Rao, GN; Singh, NK; Tinnikov, A1
Kim, MS; Lee, DH; Oh, DK; Song, YS; Yoon, DY1
Bentley, MG; Costantini, M; Ianora, A; Romano, G; Ruocco, N; Varrella, S1
Gorina, SS; Grechkin, AN; Hamberg, M; Ilyina, TM; Mukhitova, FK; Mukhtarova, LS; Toporkova, YY1
Abe, Y; Adachi, J; Aida, K; Arita, M; Fukumitsu, S; Hirata, SI; Hosomi, K; Isoyama, J; Kunisawa, J; Matsunaga, A; Nagatake, T; Sawane, K; Suzuki, H; Tomonaga, T1

Reviews

1 review(s) available for 15-hydroxy-5,8,11,13,17-eicosapentaenoic acid and eicosapentaenoic acid

ArticleYear
[Endogenous ligands for PPARs].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:4

    Topics: Animals; Eicosapentaenoic Acid; Fatty Acids; Flavonoids; Leukotrienes; Ligands; Oleic Acids; Peroxisome Proliferator-Activated Receptors; Phenols; Polyphenols; Prostaglandins

2005

Trials

1 trial(s) available for 15-hydroxy-5,8,11,13,17-eicosapentaenoic acid and eicosapentaenoic acid

ArticleYear
ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation.
    Journal of lipid research, 2011, Volume: 52, Issue:5

    Topics: Adult; Aged; Arachidonate 5-Lipoxygenase; Docosahexaenoic Acids; Eicosanoids; Eicosapentaenoic Acid; Female; Fish Oils; Genotype; Humans; Leukotrienes; Lipid Metabolism; Male; Middle Aged; Promoter Regions, Genetic; Young Adult

2011

Other Studies

16 other study(ies) available for 15-hydroxy-5,8,11,13,17-eicosapentaenoic acid and eicosapentaenoic acid

ArticleYear
Guinea pig epidermis generates putative anti-inflammatory metabolites from fish oil polyunsaturated fatty acids.
    Lipids, 1989, Volume: 24, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Docosahexaenoic Acids; Eicosapentaenoic Acid; Epidermis; Fatty Acids, Unsaturated; Fish Oils; Guinea Pigs; Leukotriene B4; Lipoxygenase Inhibitors; Male; Psoriasis; Tumor Cells, Cultured

1989
Mass spectrometry of underivatized 15-hydroxyeicosatetraenoic acid and 15-hydroxyeicosapentaenoic acid.
    Biomedical & environmental mass spectrometry, 1988, Volume: 17, Issue:6

    Topics: Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; Hydroxyeicosatetraenoic Acids; Mass Spectrometry

1988
15-Hydroperoxyeicosapentaenoic acid inhibits arachidonic acid metabolism in rabbit platelets more potently than eicosapentaenoic acid.
    Biochimica et biophysica acta, 1996, May-20, Volume: 1300, Issue:3

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Blood Platelets; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Free Radical Scavengers; Hydroxyeicosatetraenoic Acids; Hydroxyl Radical; Lipoxygenase; Male; Prostaglandin-Endoperoxide Synthases; Rabbits; Thromboxane B2

1996
Effects of eicosapentaenoic acid and its 15-hydroperoxy and 15-hydroxy derivatives on glucosamine synthetase activity in rabbit gastric mucosa.
    Biochemistry and molecular biology international, 1998, Volume: 46, Issue:1

    Topics: Animals; Eicosapentaenoic Acid; Ferrous Compounds; Gastric Mucosa; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Male; Pyloric Antrum; Rabbits

1998
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing.
    The Journal of experimental medicine, 2000, Oct-16, Volume: 192, Issue:8

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cells, Cultured; Cyclooxygenase 2; Eicosapentaenoic Acid; Endothelium, Vascular; Fatty Acids, Omega-3; Humans; In Vitro Techniques; Indomethacin; Inflammation; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Microcirculation; Microsomes; Neutrophils; Prostaglandin-Endoperoxide Synthases; Receptors, Leukotriene B4; Recombinant Proteins; Transfection; Tumor Necrosis Factor-alpha; Umbilical Veins

2000
Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells.
    Molecular cancer research : MCR, 2005, Volume: 3, Issue:9

    Topics: Arachidonate 15-Lipoxygenase; Cell Cycle Proteins; Cell Division; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; DNA-Activated Protein Kinase; DNA-Binding Proteins; Eicosapentaenoic Acid; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Linoleic Acids; Lipoxygenase Inhibitors; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2005
Probing the skin permeation of eicosapentaenoic acid and ketoprofen 2. Comparative depth profiling and metabolism of eicosapentaenoic acid.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2007, Volume: 67, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Culture Media; Data Interpretation, Statistical; Diffusion Chambers, Culture; Eicosapentaenoic Acid; Fish Oils; In Vitro Techniques; Ketoprofen; Permeability; Receptors, Drug; Skin Absorption; Swine

2007
Mechanisms for anti-inflammatory effects of 1-[15(S)-hydroxyeicosapentaenoyl] lysophosphatidylcholine, administered intraperitoneally, in zymosan A-induced peritonitis.
    British journal of pharmacology, 2011, Volume: 162, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Eicosapentaenoic Acid; In Vitro Techniques; Inflammation Mediators; Injections, Intraperitoneal; Leukocytes; Leukotriene B4; Leukotriene C4; Lysophosphatidylcholines; Male; Mice; Mice, Inbred ICR; Oligopeptides; Oxidation-Reduction; Peritonitis; Structure-Activity Relationship; Zymosan

2011
Involvement of 15-lipoxygenase in the inflammatory arthritis.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:7

    Topics: Animals; Arachidonate 15-Lipoxygenase; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Chromones; Eicosapentaenoic Acid; Fibroblasts; Fluorenes; Humans; I-kappa B Kinase; Interleukin-1beta; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proline; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Messenger; RNA, Small Interfering; Synovial Membrane; Thiocarbamates; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2012
Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus.
    Marine drugs, 2013, Nov-13, Volume: 11, Issue:11

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Microbial Sensitivity Tests; Propionibacterium acnes; Skin; Staphylococcus aureus

2013
15-PGDH/15-KETE plays a role in hypoxia-induced pulmonary vascular remodeling through ERK1/2-dependent PAR-2 pathway.
    Cellular signalling, 2014, Volume: 26, Issue:7

    Topics: Animals; Arachidonic Acids; Cell Cycle; Cell Cycle Proteins; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Eicosapentaenoic Acid; Extracellular Signal-Regulated MAP Kinases; Humans; Hydroxyprostaglandin Dehydrogenases; Hypertension, Pulmonary; Lung; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Random Allocation; Rats; Rats, Wistar; Receptor, PAR-2; RNA Interference; RNA, Small Interfering; Vascular Remodeling

2014
12/15-Lipoxygenase-dependent ROS production is required for diet-induced endothelial barrier dysfunction.
    Journal of lipid research, 2015, Volume: 56, Issue:3

    Topics: Animals; Aorta; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Capillary Permeability; Cell Adhesion Molecules; Dietary Fats; Eicosapentaenoic Acid; Endothelium, Vascular; Mice; Mice, Knockout; Reactive Oxygen Species; Receptors, Cell Surface; Tight Junctions; Xanthine Oxidase

2015
15-Hydroxyeicosatetraenoic Acid Inhibits Phorbol-12-Myristate-13-Acetate-Induced MUC5AC Expression in NCI-H292 Respiratory Epithelial Cells.
    Journal of microbiology and biotechnology, 2015, Volume: 25, Issue:5

    Topics: Cell Line, Tumor; Eicosapentaenoic Acid; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Models, Biological; Mucin 5AC; Phorbol Esters; Respiratory Mucosa

2015
First Morphological and Molecular Evidence of the Negative Impact of Diatom-Derived Hydroxyacids on the Sea Urchin Paracentrotus lividus.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 151, Issue:2

    Topics: Animals; Diatoms; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Paracentrotus; Water Pollutants, Chemical

2016
Identification of CYP443D1 (CYP74 clan) of Nematostella vectensis as a first cnidarian epoxyalcohol synthase and insights into its catalytic mechanism.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017, Volume: 1862, Issue:10 Pt A

    Topics: Animals; Catalysis; Cloning, Molecular; Cytochrome P-450 Enzyme System; Eicosapentaenoic Acid; Linoleic Acids; Lipid Peroxides; Sea Anemones; Substrate Specificity

2017
Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice.
    Nutrients, 2019, 11-22, Volume: 11, Issue:12

    Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Disease Models, Animal; Eicosapentaenoic Acid; Eosinophils; Female; Inflammation; Linseed Oil; Lipid Metabolism; Mice; Mice, Inbred C57BL; PPAR gamma; Rhinitis, Allergic

2019