15-acetyldeoxynivalenol and tryptophol

15-acetyldeoxynivalenol has been researched along with tryptophol* in 1 studies

Other Studies

1 other study(ies) available for 15-acetyldeoxynivalenol and tryptophol

ArticleYear
Multiple metabolic pathways for metabolism of l-tryptophan in Fusarium graminearum.
    Canadian journal of microbiology, 2017, Volume: 63, Issue:11

    Fusarium graminearum is a plant pathogen that can cause the devastating cereal grain disease fusarium head blight in temperate regions of the world. Previous studies have shown that F. graminearum can synthetize indole-3-acetic acid (auxin) using l-tryptophan (L-TRP)-dependent pathways. In the present study, we have taken a broader approach to examine the metabolism of L-TRP in F. graminearum liquid culture. Our results showed that F. graminearum was able to transiently produce the indole tryptophol when supplied with L-TRP. Comparative gene expression profiling between L-TRP-treated and control cultures showed that L-TRP treatment induced the upregulation of a series of genes with predicted function in the metabolism of L-TRP via anthranilic acid and catechol towards the tricarboxylic acid cycle. It is proposed that this metabolic activity provides extra energy for 15-acetyldeoxynivalenol production, as observed in our experiments. This is the first report of the use of L-TRP to increase energy resources in a Fusarium species.

    Topics: Edible Grain; Fusarium; Gene Expression Profiling; Indoleacetic Acids; Indoles; Metabolic Networks and Pathways; Microarray Analysis; Trichothecenes; Triticum; Tryptophan

2017