Compounds > 14,15-epoxy-5,8,11-eicosatrienoic acid

14,15-epoxy-5,8,11-eicosatrienoic acid and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's5 (38.46)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braden, G; Catella, F; Fitzgerald, DJ; FitzGerald, GA; Lawson, J; Shipp, E1
Campbell, WB; Falck, JR; Rosolowsky, M1
Chatterjee, P; Fang, X; Kaduce, TL; Spector, AA; VanRollins, M; Weintraub, NL1
Huang, S; Konieczkowski, M; Schelling, JR; Sedor, JR1
Campbell, WB; Hillard, CJ; Kurian, J; Li, P; Pratt, PF1
Campbell, WB; Deeter, C; Falck, JR; Gauthier, KM; Ingraham, RH; Li, PL1
Bondlela, M; Campbell, WB; Deeter, C; Falck, JR; Gauthier, KM; Krishna, UM; Reddy, YK1
Campbell, WB; Falck, JR; Gopal, VR; Holmes, BB; Kishore, RV; Sangras, B; Yang, W; Yi, XY1
Behm, DJ; Burns-Kurtis, CL; Douglas, SA; Ogbonna, A; Wu, C1
Albadine, R; Morin, C; Rousseau, E; Senouvo, FY; Sirois, C; Tabet, Y1
Rizcallah, E; Rousseau, É; Sirois, C; Sirois, M; Tabet, Y1
Froogh, G; Huang, A; Jiang, H; Kandhi, S; Luo, M; Qin, J; Sun, D; Wolin, MS1
Alkayed, NJ; Barnes, AP; Fan, W; Kaul, S; Liu, X; Nelson, JW; Qian, ZY; Xiao, X; Xie, F1

Other Studies

13 other study(ies) available for 14,15-epoxy-5,8,11-eicosatrienoic acid and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

ArticleYear
Biosynthesis of P450 products of arachidonic acid in humans: increased formation in cardiovascular disease.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Angina, Unstable; Angioplasty, Balloon, Coronary; Arachidonic Acid; Arachidonic Acids; Colforsin; Cyclic AMP; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Female; Humans; Oxygenases; Platelet Activation; Pre-Eclampsia; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Thrombin

1991
Synthesis and biological activity of epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Cattle; Cells, Cultured; Coronary Vessels; Dogs; Endothelium, Vascular; Epoprostenol; Hydroxyeicosatetraenoic Acids; Muscle, Smooth, Vascular; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Vasodilation

1991
Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids.
    Circulation research, 1997, Volume: 81, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Bradykinin; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane A2; Vasoconstrictor Agents; Vasodilation

1997
Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells.
    Kidney international, 1999, Volume: 55, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Aristolochic Acids; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Fatty Acids, Unsaturated; Glomerular Mesangium; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Leukotrienes; Lipid Peroxides; Mitogen-Activated Protein Kinases; Nephritis; Phenanthrenes; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Rats; Signal Transduction; Stearic Acids; Tritium; Vasoconstrictor Agents

1999
Endothelium-independent, ouabain-sensitive relaxation of bovine coronary arteries by EETs.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Benzopyrans; Biological Factors; Bradykinin; Cardiotonic Agents; Cattle; Coronary Vessels; Dihydropyridines; Electrophysiology; Endothelium, Vascular; Membrane Potentials; Muscle, Smooth, Vascular; Nitroprusside; Ouabain; Peptides; Potassium; Potassium Channels; Tritium; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2001
14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Acetylcholine; Animals; Calcium; Cattle; Charybdotoxin; Coronary Vessels; Electric Conductivity; Endothelium, Vascular; Enzyme Inhibitors; Epoxide Hydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hydroxyeicosatetraenoic Acids; Muscle Relaxation; Muscle, Smooth, Vascular; Peptides; Potassium Channels

2002
14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries.
    Circulation research, 2002, May-17, Volume: 90, Issue:9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Benzimidazoles; Benzopyrans; Bradykinin; Cattle; Coronary Vessels; Dihydropyridines; Dose-Response Relationship, Drug; Endothelium, Vascular; Iloprost; In Vitro Techniques; Kidney Cortex; Male; Microsomes; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2002
Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Binding, Competitive; Cattle; Cell Membrane; Coronary Vessels; Humans; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Ligands; Molecular Structure; Peptides; Subcellular Fractions; Sulfonamides; U937 Cells; Vasodilation; Vasodilator Agents

2007
Epoxyeicosatrienoic acids function as selective, endogenous antagonists of native thromboxane receptors: identification of a novel mechanism of vasodilation.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Aorta, Thoracic; Arachidonic Acids; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Male; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Splanchnic Circulation; Trachea; TRPV Cation Channels; Vascular Resistance; Vasoconstriction; Vasodilation

2009
Improved bioavailability of epoxyeicosatrienoic acids reduces TP-receptor agonist-induced tension in human bronchi.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Benzoates; Blotting, Western; Bronchi; Cells, Cultured; Eicosapentaenoic Acid; Electrophoresis, Polyacrylamide Gel; Epoxide Hydrolases; Epoxy Compounds; Fluorescent Antibody Technique; Guinea Pigs; Humans; Mice; Muscle Tonus; Muscle, Smooth; Myocytes, Smooth Muscle; Rats; Receptors, Prostaglandin E; Receptors, Thromboxane; Signal Transduction; Thromboxane A2; Urea

2011
Relationship between bradykinin-induced relaxation and endogenous epoxyeicosanoid synthesis in human bronchi.
    American journal of physiology. Lung cellular and molecular physiology, 2013, Apr-15, Volume: 304, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Amides; Bradykinin; Bronchi; Dose-Response Relationship, Drug; Eicosanoids; Humans; In Vitro Techniques; Membrane Potentials; Muscle Relaxation; Respiratory Muscles

2013
EET-dependent potentiation of pulmonary arterial pressure: sex-different regulation of soluble epoxide hydrolase.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Dec-15, Volume: 309, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arterial Pressure; Epoxide Hydrolases; Female; Hypertension, Pulmonary; Male; Mice; Mice, Knockout; Pulmonary Artery; Sex Characteristics; Vasoconstriction

2015
Functional screening for G protein-coupled receptor targets of 14,15-epoxyeicosatrienoic acid.
    Prostaglandins & other lipid mediators, 2017, Volume: 132

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; beta-Arrestins; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Evaluation, Preclinical; Extracellular Signal-Regulated MAP Kinases; HEK293 Cells; Humans; Intracellular Space; Mesenteric Arteries; Mice; Oocytes; Phosphorylation; Protein Transport; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Vasoconstriction; Xenopus

2017