14,15-epoxy-5,8,11-eicosatrienoic acid and 14,15-dihydroxyeicosatrienoic acid

14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with 14,15-dihydroxyeicosatrienoic acid in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (21.05)18.2507
2000's8 (42.11)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhatt, RK; Campbell, WB; Falck, JR; Hanke, CJ; Nithipatikom, K1
Fang, X; Kaduce, TL; Spector, AA; Weintraub, NL1
Fang, X; Kaduce, TL; Moore, SA; Rich, G; Spector, AA; Stoll, LL; Weintraub, NL1
Chatterjee, P; Fang, X; Kaduce, TL; Spector, AA; VanRollins, M; Weintraub, NL1
Benech, H; Chéron, G; Colin, I; Cresteil, T; Pruvost, A; Tréluyer, JM1
Campbell, WB; Deeter, C; Falck, JR; Gauthier, KM; Ingraham, RH; Li, PL1
Cox, R; Oleksiak, MF; Parker, C; Qu, W; Stegeman, JJ; Wu, S; Zeldin, DC1
Buerkle, MA; Campbell, WB; Gloe, T; Krötz, F; Nithipatikom, K; Pohl, U; Riexinger, T; Sohn, HY1
Fang, X; Hammock, BD; Harmon, SD; Hu, S; McCaw, RB; Rice, JB; Spector, AA; Weintraub, NL1
Baewer, DV; Campbell, WB; Falck, JR; Gauthier, KM; Hillard, CJ; Hittner, S; Nithipatikom, K; Reddy, DS1
Falck, JR; Fang, X; Harmon, S; Hu, S; Liu, Y; Sangras, B; Snyder, GD; Spector, AA; Weintraub, NL; Xu, B; Yao, J1
Chiang, PC; Fujiwara, H; Ghosh, S; Roberds, SL; Selbo, JG; Wahlstrom, JL1
Campbell, WB; Falck, JR; Gauthier, KM; Kopf, PG; Zhang, DX1
Hammock, BD; Huby, M; Hwang, SH; Morisseau, C; Schebb, NH1
Booth-Genthe, C; Callahan, JF; Licea-Perez, H; Peck, B; Zhu, P1
Bass, A; Edin, ML; Ellis, K; Hinderliter, AL; Lee, CR; Lih, FB; Poloyac, SM; Schuck, RN; Stouffer, GA; Theken, KN; Tomer, KB; Tran, B; Wu, MC; Zeldin, DC1
Alkayed, NJ; Nelson, JW; Subrahmanyan, RM; Summers, SA; Xiao, X1
Guo, Y; Peng, R; Shen, L; Xu, D; Yang, T; Zhao, S1
Joiakim, A; Kim, H; Park, JA; Putt, DA; Santos, JM; Taylor, RN1

Other Studies

19 other study(ies) available for 14,15-epoxy-5,8,11-eicosatrienoic acid and 14,15-dihydroxyeicosatrienoic acid

ArticleYear
Determination of 14,15-epoxyeicosatrienoic acid and 14,15-dihydroxyeicosatrienoic acid by fluoroimmunoassay.
    Analytical biochemistry, 1997, Mar-15, Volume: 246, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antibodies; Cattle; Cells, Cultured; Cross Reactions; Endothelium, Vascular; Fluoroimmunoassay; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Rabbits; Radioimmunoassay; Zona Glomerulosa

1997
Cytochrome P450 metabolites of arachidonic acid: rapid incorporation and hydration of 14,15-epoxyeicosatrienoic acid in arterial smooth muscle cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 57, Issue:4-5

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arteries; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraenoic Acids; Muscle Relaxation; Muscle, Smooth, Vascular; Phospholipids; Swine

1997
14,15-Epoxyeicosatrienoic acid inhibits prostaglandin E2 production in vascular smooth muscle cells.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Aorta; Cell Division; Cells, Cultured; Cerebrovascular Circulation; Dinoprostone; Hydroxyeicosatetraenoic Acids; Microcirculation; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Swine

1998
Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arteries; Bradykinin; Cells, Cultured; Chalcone; Chalcones; Coenzyme A Ligases; Coronary Vessels; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Epoxide Hydrolases; Hydroxyeicosatetraenoic Acids; Lipid Metabolism; Phospholipids; Swine; Vasodilation

1999
Ontogenesis of CYP2C-dependent arachidonic acid metabolism in the human liver: relationship with sudden infant death syndrome.
    Pediatric research, 2000, Volume: 47, Issue:5

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Age Factors; Arachidonic Acid; Arachidonic Acids; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Humans; Hydroxyeicosatetraenoic Acids; Infant; Isoenzymes; Liver; Microsomes, Liver; NADP; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sudden Infant Death; Up-Regulation

2000
14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Acetylcholine; Animals; Calcium; Cattle; Charybdotoxin; Coronary Vessels; Electric Conductivity; Endothelium, Vascular; Enzyme Inhibitors; Epoxide Hydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hydroxyeicosatetraenoic Acids; Muscle Relaxation; Muscle, Smooth, Vascular; Peptides; Potassium Channels

2002
Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase.
    Archives of biochemistry and biophysics, 2003, Mar-15, Volume: 411, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Amino Acid Sequence; Animals; Arachidonic Acid; Benzphetamine; Cloning, Molecular; Conserved Sequence; Cytochrome P-450 Enzyme System; Fasting; Fundulidae; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Male; Molecular Sequence Data; Multigene Family; Organ Specificity; Phylogeny; Rats; Rats, Inbred F344; RNA, Messenger; Sequence Alignment; Tetradecanoylphorbol Acetate; Vertebrates

2003
Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:3

    Topics: 8,11,14-Eicosatrienoic Acid; Apamin; Aryl Hydrocarbon Hydroxylases; Biological Factors; Blood Platelets; Cells, Cultured; Charybdotoxin; Cytochrome P-450 CYP2C9; Endothelial Cells; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Ion Channels; Membrane Potentials; Peptides; Platelet Adhesiveness; Platelet Aggregation; Potassium Channels; Recombinant Fusion Proteins; Transfection; Umbilical Veins

2004
Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Cells, Cultured; Cyclohexanes; Endothelium, Vascular; Epoxide Hydrolases; Epoxy Compounds; Humans; Hydroxyeicosatetraenoic Acids; Lauric Acids; Lipid Metabolism; Muscle, Smooth, Vascular; Oxidation-Reduction; Saphenous Vein; Solubility; Tritium; Vasodilator Agents

2004
Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:3

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Cattle; Cells, Cultured; Coronary Vessels; Endocannabinoids; Endothelium, Vascular; Glycerides; Hydroxyeicosatetraenoic Acids; Vasodilation

2005
14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Epoxide Hydrolases; Epoxy Compounds; Humans; PPAR alpha; Urea

2006
Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 102, Issue:5

    Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Chromatography, Liquid; Disease Models, Animal; Epoxide Hydrolases; Hypertension; Male; Nanoparticles; Particle Size; Rats; Rats, Sprague-Dawley; Solubility; Suspensions; Tandem Mass Spectrometry; Urea

2008
Angiotensin II regulates adrenal vascular tone through zona glomerulosa cell-derived EETs and DHETs.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Arachidonic Acid; Arteries; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Epoxide Hydrolases; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Potassium Channels; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Zona Glomerulosa

2011
Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors.
    Analytical and bioanalytical chemistry, 2011, Volume: 400, Issue:5

    Topics: 8,11,14-Eicosatrienoic Acid; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Solid Phase Extraction; Tandem Mass Spectrometry

2011
Development of a semi-automated LC/MS/MS method for the simultaneous quantitation of 14,15-epoxyeicosatrienoic acid, 14,15-dihydroxyeicosatrienoic acid, leukotoxin and leukotoxin diol in human plasma as biomarkers of soluble epoxide hydrolase activity in
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Sep-01, Volume: 879, Issue:25

    Topics: 8,11,14-Eicosatrienoic Acid; Biomarkers; Chromatography, Liquid; Epoxide Hydrolases; Female; Humans; Linoleic Acids; Male; Reproducibility of Results; Sensitivity and Specificity; Stearic Acids; Tandem Mass Spectrometry

2011
Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease.
    Atherosclerosis, 2012, Volume: 222, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Age Factors; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Eicosanoids; Epoxide Hydrolases; Female; Humans; Hydroxyeicosatetraenoic Acids; Hydroxylation; Male; Middle Aged; North Carolina; Obesity; Regression Analysis; Risk Assessment; Risk Factors; Severity of Illness Index; Smoking; Tandem Mass Spectrometry

2012
Soluble epoxide hydrolase dimerization is required for hydrolase activity.
    The Journal of biological chemistry, 2013, Mar-15, Volume: 288, Issue:11

    Topics: 8,11,14-Eicosatrienoic Acid; Dimerization; DNA Mutational Analysis; Epoxide Hydrolases; Genetic Complementation Test; HEK293 Cells; Humans; Hydrolases; Kinetics; Models, Molecular; Mutation; Polymorphism, Genetic; Solubility; Transfection

2013
The role of 14,15-dihydroxyeicosatrienoic acid levels in inflammation and its relationship to lipoproteins.
    Lipids in health and disease, 2013, Oct-23, Volume: 12

    Topics: 8,11,14-Eicosatrienoic Acid; Aged; C-Reactive Protein; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Female; Humans; Inflammation; Male; Middle Aged; Statistics, Nonparametric; Triglycerides

2013
The role of soluble epoxide hydrolase in preeclampsia.
    Medical hypotheses, 2017, Volume: 108

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Antihypertensive Agents; Blood Pressure; Epoprostenol; Epoxide Hydrolases; Female; Glucuronidase; Humans; Hypertension; Maternal Age; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vasoconstriction; Vasodilator Agents; Young Adult

2017