Compounds > 13-azaprostanoic acid
Page last updated: 2024-09-03

13-azaprostanoic acid and indomethacin

13-azaprostanoic acid has been researched along with indomethacin in 6 studies

Compound Research Comparison

Studies
(13-azaprostanoic acid)		Trials
(13-azaprostanoic acid)		Recent Studies (post-2010)
(13-azaprostanoic acid)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
420029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomy13-azaprostanoic acid (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Enke, SE; Le Breton, GC; Venton, DL1
Kaibuchi, K; Kikuchi, A; Takai, Y; Tanimoto, T; Tsuda, T1
Brace, LD; Le Breton, GC; Venton, DL1
Brace, LD; Fareed, J1
Brace, LD; Fareed, J; Issleib, S1
Le Breton, GC; Venton, DL1

Other Studies

6 other study(ies) available for 13-azaprostanoic acid and indomethacin

ArticleYear
Azaprostanoic acid derivatives. Inhibitors of arachidonic acid induced platelet aggregation.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:7

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Binding Sites; Cattle; Cyclooxygenase Inhibitors; Fatty Acids; Humans; In Vitro Techniques; Male; Methods; Molecular Conformation; Platelet Aggregation; Prostanoic Acids; Seminal Vesicles; Structure-Activity Relationship

1979
Enhancement of collagen-induced phosphoinositide turnover by thromboxane A2 analogue through Ca2+ mobilization in human platelets.
    FEBS letters, 1985, Nov-11, Volume: 192, Issue:1

    Topics: Blood Platelets; Calcimycin; Calcium; Collagen; Cytoplasm; Humans; Indomethacin; Myosins; Phosphatidic Acids; Phosphatidylinositols; Phosphorylation; Prostanoic Acids; Thromboxane A2

1985
Thromboxane A2/prostaglandin H2 mobilizes calcium in human blood platelets.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 2

    Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Chlortetracycline; Epoprostenol; Humans; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostanoic Acids; Stimulation, Chemical; Thromboxane A2; Thromboxanes

1985
An objective assessment of the interaction of heparin and its fractions with human platelets.
    Seminars in thrombosis and hemostasis, 1985, Volume: 11, Issue:2

    Topics: Adenosine Triphosphate; Blood Platelets; Dose-Response Relationship, Drug; Heparin; Humans; Indomethacin; Platelet Aggregation; Platelet Factor 4; Prostanoic Acids; Protamines; Thromboxane B2

1985
Heparin-induced platelet aggregation is inhibited by antagonists of the thromboxane pathway.
    Thrombosis research, 1985, Aug-15, Volume: 39, Issue:4

    Topics: Aspirin; Bleeding Time; Heparin; Heparin Antagonists; Humans; Indomethacin; Platelet Aggregation; Prostanoic Acids; Thromboxanes

1985
Thromboxane A2 receptor antagonism selectively reverses platelet aggregation.
    Advances in prostaglandin and thromboxane research, 1980, Volume: 6

    Topics: Adenosine Diphosphate; Arachidonic Acids; Epinephrine; Fatty Acids; Humans; Indomethacin; Kinetics; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostanoic Acids

1980