Compounds > 13,14-dihydro-15-ketoprostaglandin e1
Page last updated: 2024-09-05

13,14-dihydro-15-ketoprostaglandin e1 and alprostadil

13,14-dihydro-15-ketoprostaglandin e1 has been researched along with alprostadil in 6 studies

Compound Research Comparison

Studies
(13,14-dihydro-15-ketoprostaglandin e1)		Trials
(13,14-dihydro-15-ketoprostaglandin e1)		Recent Studies (post-2010)
(13,14-dihydro-15-ketoprostaglandin e1)		Studies
(alprostadil)		Trials
(alprostadil)		Recent Studies (post-2010) (alprostadil)
7107,136864761

Protein Interaction Comparison

ProteinTaxonomy13,14-dihydro-15-ketoprostaglandin e1 (IC50)alprostadil (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)2.3
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.0358

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gallacher, AF; Harrison, NW; Johnston, TA; Kelly, RW1
Bonn, R; Cawello, W; Müller, R; Schweer, H; Seyberth, HW1
Meese, CO; Schweer, H; Seyberth, HW; Watzer, B1
Gieler, U; Happle, R; Krauss, M; Leonhardt, A; Schweer, H; Seyberth, HW1
Kalow, W; Mueller, R; Rady-Pentek, P; Tang, BK1
Neumann, I; O'Grady, J; Peskar, BA; Rogatti, W; Sinzinger, H1

Trials

1 trial(s) available for 13,14-dihydro-15-ketoprostaglandin e1 and alprostadil

ArticleYear
Metabolism and pharmacokinetics of prostaglandin E1 administered by intravenous infusion in human subjects.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:3

    Topics: Adult; Alprostadil; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Infusions, Intravenous; Male; Single-Blind Method

1994

Other Studies

5 other study(ies) available for 13,14-dihydro-15-ketoprostaglandin e1 and alprostadil

ArticleYear
The measurement of the main PGE metabolite, 13,14-dihydro-15-keto prostaglandin E by radioimmunoassay using methyl oxime stabilization.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 45, Issue:3

    Topics: Alprostadil; Amino Acid Sequence; Animals; Cross Reactions; Female; Humans; Hydroxylamines; Molecular Sequence Data; Oximes; Pregnancy; Rabbits; Radioimmunoassay

1992
Determination of prostaglandin E1 and its main plasma metabolites 15-keto-prostaglandin E0 and prostaglandin E0 by gas chromatography/negative ion chemical ionization triple-stage quadrupole mass spectrometry.
    Biological mass spectrometry, 1994, Volume: 23, Issue:3

    Topics: Alprostadil; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques

1994
In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis.
    The British journal of dermatology, 1997, Volume: 136, Issue:3

    Topics: Adolescent; Adult; Alprostadil; Dermatitis, Atopic; Dinoprostone; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Skin

1997
Interindividual variation in the enzymatic 15-keto-reduction of 13,14-dihydro-15-keto-prostaglandin E1 in human liver and in human erythrocytes.
    European journal of clinical pharmacology, 1997, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Alprostadil; Child; Cytosol; Erythrocytes; Female; Humans; Hydrogen-Ion Concentration; Individuality; Liver; Male; Oxidation-Reduction; Polymorphism, Genetic

1997
Effects of prostaglandin E1 metabolites on the induction of arterial thromboresistance.
    Prostaglandins & other lipid mediators, 1998, Volume: 55, Issue:5-6

    Topics: Alprostadil; Animals; Aorta; Arteries; Blood Platelets; Endothelium, Vascular; Humans; Iliac Artery; In Vitro Techniques; Male; Perfusion; Rabbits; Thrombosis

1998