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11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid

11-hydroxy-delta(9)-tetrahydrocannabinol has been researched along with 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.56)18.7374
1990's2 (5.13)18.2507
2000's15 (38.46)29.6817
2010's21 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foltz, RL; Hidy, BJ1
Basteyns, BJ; Goodall, CR1
Cone, E; Foltz, R; Haughey, H; Huestis, M; Rollins, D; Wilkins, D1
Augsburger, M; Buclin, T; Giroud, C; Mangin, P; Ménétrey, A; Sanchez-Mazas, P1
Barnes, A; Gustafson, RA; Huestis, MA; Levine, B; Moolchan, ET1
Maralikova, B; Weinmann, W1
Fraser, AD; Worth, D1
Clements, TT; Coles, R; McMillin, GA; Nelson, GJ; Urry, FM1
Barnes, A; Goodwin, RS; Gustafson, RA; Huestis, MA; Moolchan, ET; Nebro, W1
Barnes, AJ; Huestis, MA; Karschner, EL; Lowe, RH; Schwilke, EW1
Abraham, TT; Darwin, WD; Huestis, MA; Lowe, RH; Pirnay, SO1
Pötsch, L; Skopp, G1
de Vries, I; Hoek, J; Hunault, CC; Kelholt-Dijkman, HH; Kruidenier, M; Leenders, ME; Mensinga, TT; Meulenbelt, J1
Boellaard, R; Bossong, MG; Kahn, RS; Lammertsma, AA; Ramsey, NF; Schuit, RC; van Berckel, BN; van Gerven, JM; Windhorst, AD; Zuurman, L1
De Boeck, G; Del Mar Ramirez Fernandez, M; Lopez-Rivadulla, M; Samyn, N; Wood, M1
Coulter, C; Crompton, K; Miller, E; Moore, C1
Darwin, WD; Goodwin, RS; Gorelick, DA; Huestis, MA; Karschner, EL; Kelly, DL; Lowe, RH; Schwilke, EW; Schwope, DM1
Cadet, JL; Darwin, WD; Herning, RI; Huestis, MA; Karschner, EL; Lowe, RH; Schwilke, EW1
Barnes, AJ; Huestis, MA; Karschner, EL; Lowe, RH; Scheidweiler, KB1
Becker, J; Drobnik, S; Kaufmann, T; Kuntz, V; Röhrich, J; Schimmel, I; Urban, R; Zörntlein, S1
Darwin, WD; Goodwin, RS; Huestis, MA; Karschner, EL; Wright, S1
Gorelick, DA; Huestis, MA; Karschner, EL; Schwope, DM1
Darwin, WD; Goodwin, RS; Gorelick, DA; Huestis, MA; Kelly, DL; Milman, G; Schwilke, EW; Schwope, DM1
Arendt, M; Fohlmann, A; Hjorthøj, CR; Larsen, AM; Nordentoft, M1
Bosker, WM; Gorelick, DA; Huestis, MA; Ramaekers, JG; Schwope, DM1
Baldinger, R; Brenneisen, R; Fagagnini, S; Goldman, B; Joerger, M; Schneider, U; Weber, M; Wilkins, J1
Barnes, AJ; Desrosiers, NA; Gorelick, DA; Huestis, MA; Lee, D; Milman, G; Schwope, DM1
Fabritius, M; Giroud, C; Mangin, P; Staub, C1
Babić, S; Nestić, M; Pavlović, DM; Sutlović, D1
Concheiro-Guisan, M; Desrosiers, NA; Gorelick, DA; Himes, SK; Huestis, MA; Scheidweiler, KB1
Hanisch, S; Paulke, A; Pogoda, W; Toennes, SW; Wunder, C1
Bosker, WM; Goodwin, RS; Hirvonen, J; Huestis, MA; Karschner, EL; Ramaekers, JG; Swortwood, MJ1
Bonnet, U; Borda, T; Scherbaum, N; Specka, M1
Erdmann, F; Heinl, S; Lerch, O; Purschke, K; Veit, F1
Miller, R; Shan, X; Sprague, J; Tiscione, NB; Yeatman, DT1
McMillin, GA; Metz, TD; Scroggin, TL; Wu, F1
Christensen, M; Lisano, JK; Mathias, AB; Phillips, KT; Quinn, CJ; Smith, JD; Smoak, P; Stewart, LK1
Franz, T; Musshoff, F; Schwarz, G; Skopp, G1
Castro, AL; Franco, JM; Melo, P; Tarelho, S1

Trials

7 trial(s) available for 11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid

ArticleYear
Delta(9)-tetrahydrocannabinol, 11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-9-carboxy-delta(9)-tetrahydrocannabinol in human plasma after controlled oral administration of cannabinoids.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:4

    Topics: Administration, Oral; Body Mass Index; Cannabinoids; Capsules; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Drug Administration Schedule; Gas Chromatography-Mass Spectrometry; Humans; Metabolic Clearance Rate; Plant Oils; Psychotropic Drugs

2006
Simultaneous GC-EI-MS determination of Delta9-tetrahydrocannabinol, 11-hydroxy-Delta9-tetrahydrocannabinol, and 11-nor-9-carboxy-Delta9-tetrahydrocannabinol in human urine following tandem enzyme-alkaline hydrolysis.
    Journal of analytical toxicology, 2007, Volume: 31, Issue:8

    Topics: Dronabinol; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Hydrolysis; Marijuana Smoking; Psychotropic Drugs; Reproducibility of Results; Sodium Hydroxide; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection

2007
Delta-9-tetrahydrocannabinol (THC) serum concentrations and pharmacological effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg THC.
    Psychopharmacology, 2008, Volume: 201, Issue:2

    Topics: Adolescent; Adult; Area Under Curve; Blood Pressure; Cannabis; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Emotions; Half-Life; Heart Rate; Humans; Male; Marijuana Smoking; Psychomotor Performance; Risk Factors; Serum; Smoking; Time Factors; Young Adult

2008
Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:3

    Topics: Administration, Inhalation; Adult; Cannabinoid Receptor Modulators; Corpus Striatum; Cross-Over Studies; Dopamine; Double-Blind Method; Dronabinol; Heart Rate; Humans; Magnetic Resonance Imaging; Male; Placebos; Positron-Emission Tomography; Psychiatric Status Rating Scales; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D3

2009
Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration.
    Clinical chemistry, 2011, Volume: 57, Issue:1

    Topics: Adult; Cannabidiol; Cannabis; Double-Blind Method; Dronabinol; Drug Combinations; Female; Humans; Male; Marijuana Abuse; Mouth Mucosa; Plant Extracts; Young Adult

2011
Correlations and agreement between delta-9-tetrahydrocannabinol (THC) in blood plasma and timeline follow-back (TLFB)-assisted self-reported use of cannabis of patients with cannabis use disorder and psychotic illness attending the CapOpus randomized clin
    Addiction (Abingdon, England), 2012, Volume: 107, Issue:6

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Dronabinol; Female; Humans; Male; Marijuana Abuse; Psychotic Disorders; ROC Curve; Self Report; Substance Abuse Detection

2012
Single-dose pharmacokinetics and tolerability of oral delta-9- tetrahydrocannabinol in patients with amyotrophic lateral sclerosis.
    Drug metabolism letters, 2012, Jun-01, Volume: 6, Issue:2

    Topics: Administration, Oral; Adult; Aged; Amyotrophic Lateral Sclerosis; Cannabinoid Receptor Agonists; Dose-Response Relationship, Drug; Dronabinol; Female; Heart Rate; Humans; Male; Middle Aged; Models, Biological; Prospective Studies

2012

Other Studies

32 other study(ies) available for 11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid

ArticleYear
Quantitative analysis for delta 9-THC, 11-hydroxy-delta 9-THC, and 9-carboxy-delta 9-THC in plasma using GC/CI-MS.
    NIDA research monograph, 1982, Volume: 42

    Topics: Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Time Factors

1982
A reliable method for the detection, confirmation, and quantitation of cannabinoids in blood.
    Journal of analytical toxicology, 1995, Volume: 19, Issue:6

    Topics: Automobile Driving; Cannabinoids; Dronabinol; Fluorescence Polarization; Hallucinogens; Humans; Reference Standards; Reproducibility of Results

1995
Quantitative analysis of THC, 11-OH-THC, and THCCOOH in human hair by negative ion chemical ionization mass spectrometry.
    Journal of analytical toxicology, 1995, Volume: 19, Issue:6

    Topics: Boranes; Dronabinol; Hair; Humans; Mass Spectrometry; Methylene Chloride; Reference Standards; Reproducibility of Results; Trifluoroacetic Acid

1995
Delta(9)-THC, 11-OH-Delta(9)-THC and Delta(9)-THCCOOH plasma or serum to whole blood concentrations distribution ratios in blood samples taken from living and dead people.
    Forensic science international, 2001, Dec-01, Volume: 123, Issue:2-3

    Topics: Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Marijuana Abuse; Plasma; Postmortem Changes; Substance Abuse Detection

2001
Validated method for the simultaneous determination of Delta 9-tetrahydrocannabinol (THC), 11-hydroxy-THC and 11-nor-9-carboxy-THC in human plasma using solid phase extraction and gas chromatography-mass spectrometry with positive chemical ionization.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Dec-05, Volume: 798, Issue:1

    Topics: Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity

2003
Simultaneous determination of Delta9-tetrahydrocannabinol, 11-hydroxy-Delta9-tetrahydrocannabinol and 11-nor-9-carboxy- Delta9-tetrahydrocannabinol in human plasma by high-performance liquid chromatography/tandem mass spectrometry.
    Journal of mass spectrometry : JMS, 2004, Volume: 39, Issue:5

    Topics: Calibration; Chromatography, High Pressure Liquid; Dronabinol; Humans; Mass Spectrometry; Molecular Structure; Psychotropic Drugs; Sensitivity and Specificity

2004
Urinary excretion profiles of 11-nor-9-carboxy-delta9-tetrahydrocannabinol and 11-hydroxy-delta9-THC: cannabinoid metabolites to creatinine ratio study IV.
    Forensic science international, 2004, Jul-16, Volume: 143, Issue:2-3

    Topics: Creatinine; Dronabinol; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Marijuana Abuse; Substance Abuse Detection

2004
Simultaneous analysis of the Delta9-THC metabolites 11-nor-9-carboxy-Delta9-THC and 11-hydroxy-Delta9-THC in meconium by GC-MS.
    Journal of analytical toxicology, 2005, Volume: 29, Issue:6

    Topics: Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Meconium; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection

2005
Simultaneous quantification of Delta9-tetrahydrocannabinol, 11-hydroxy-Delta9-tetrahydrocannabinol, and 11-nor-Delta9-tetrahydrocannabinol-9-carboxylic acid in human plasma using two-dimensional gas chromatography, cryofocusing, and electron impact-mass s
    Journal of chromatography. A, 2007, Sep-07, Volume: 1163, Issue:1-2

    Topics: Chromatography, Gas; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results

2007
Cannabinoid concentrations in spot serum samples 24-48 hours after discontinuation of cannabis smoking.
    Journal of analytical toxicology, 2008, Volume: 32, Issue:2

    Topics: Adult; Dronabinol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Marijuana Smoking; Microchemistry; Psychotropic Drugs

2008
Simultaneous analysis of THC and its metabolites in blood using liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Nov-15, Volume: 875, Issue:2

    Topics: Analysis of Variance; Chromatography, Liquid; Dronabinol; Drug Stability; Humans; Linear Models; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008
Tetrahydrocannabinol and two of its metabolites in whole blood using liquid chromatography-tandem mass spectrometry.
    Journal of analytical toxicology, 2008, Volume: 32, Issue:8

    Topics: Chromatography, Liquid; Dronabinol; Drug Stability; Humans; Tandem Mass Spectrometry

2008
Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC.
    Clinical chemistry, 2009, Volume: 55, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Dronabinol; Escherichia coli; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Hydrolysis; Male; Middle Aged; Young Adult

2009
Implications of plasma Delta9-tetrahydrocannabinol, 11-hydroxy-THC, and 11-nor-9-carboxy-THC concentrations in chronic cannabis smokers.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:8

    Topics: Biomarkers; Cognition Disorders; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Marijuana Smoking; Substance Abuse Detection; Substance-Related Disorders

2009
Validation of a two-dimensional gas chromatography mass spectrometry method for the simultaneous quantification of cannabidiol, Delta(9)-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC in plasma.
    Analytical and bioanalytical chemistry, 2010, Volume: 397, Issue:2

    Topics: Cannabidiol; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Sensitivity and Specificity

2010
Concentrations of delta9-tetrahydrocannabinol and 11-nor-9-carboxytetrahydrocannabinol in blood and urine after passive exposure to Cannabis smoke in a coffee shop.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:4

    Topics: Adult; Air Pollution, Indoor; Cannabis; Dronabinol; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Humans; Inhalation Exposure; Limit of Detection; Male; Middle Aged; Netherlands; Reproducibility of Results; Smoke; Time Factors

2010
Identification of recent cannabis use: whole-blood and plasma free and glucuronidated cannabinoid pharmacokinetics following controlled smoked cannabis administration.
    Clinical chemistry, 2011, Volume: 57, Issue:10

    Topics: Adolescent; Adult; Cannabidiol; Cannabinoids; Cannabinol; Cannabis; Dronabinol; Female; Glucuronides; Humans; Male; Marijuana Abuse; Middle Aged; Substance Abuse Detection; Young Adult

2011
Oral fluid and plasma cannabinoid ratios after around-the-clock controlled oral Δ(9)-tetrahydrocannabinol administration.
    Clinical chemistry, 2011, Volume: 57, Issue:11

    Topics: Adolescent; Adult; Dronabinol; Feasibility Studies; Humans; Male; Plasma; Saliva; Self Administration; Substance Abuse Detection; Time Factors; Young Adult

2011
Psychomotor performance, subjective and physiological effects and whole blood Δ⁹-tetrahydrocannabinol concentrations in heavy, chronic cannabis smokers following acute smoked cannabis.
    Journal of analytical toxicology, 2012, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Biotransformation; Cohort Studies; Dronabinol; Drug Tolerance; Female; Forensic Toxicology; Heart Rate; Humans; Limit of Detection; Male; Marijuana Smoking; Middle Aged; Psychomotor Performance; Stereoisomerism; Substance Abuse Detection; Young Adult

2012
On-site test for cannabinoids in oral fluid.
    Clinical chemistry, 2012, Volume: 58, Issue:10

    Topics: Adolescent; Adult; Cannabidiol; Cannabinoids; Cannabinol; Dronabinol; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Reference Values; Saliva; Sensitivity and Specificity; Substance Abuse Detection; Young Adult

2012
Distribution of free and conjugated cannabinoids in human bile samples.
    Forensic science international, 2012, Nov-30, Volume: 223, Issue:1-3

    Topics: Bile; Cannabinoids; Chromatography, Liquid; Dronabinol; Forensic Toxicology; Humans; Limit of Detection; Psychotropic Drugs; Tandem Mass Spectrometry

2012
Molecularly imprinted solid phase extraction for simultaneous determination of Δ9-tetrahydrocannabinol and its main metabolites by gas chromatography-mass spectrometry in urine samples.
    Forensic science international, 2013, Sep-10, Volume: 231, Issue:1-3

    Topics: Dronabinol; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Limit of Detection; Molecular Imprinting; Solid Phase Extraction

2013
Phase I and II cannabinoid disposition in blood and plasma of occasional and frequent smokers following controlled smoked cannabis.
    Clinical chemistry, 2014, Volume: 60, Issue:4

    Topics: Adult; Chromatography, Liquid; Dronabinol; Female; Glucuronides; Humans; Male; Marijuana Smoking; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Tandem Mass Spectrometry; Tissue Distribution; Young Adult

2014
Pitfall in cannabinoid analysis--detection of a previously unrecognized interfering compound in human serum.
    Analytical and bioanalytical chemistry, 2015, Volume: 407, Issue:2

    Topics: Artifacts; Calibration; Cannabinoids; Chromatography, High Pressure Liquid; Dronabinol; Forensic Toxicology; Humans; Isomerism; Limit of Detection; Marijuana Smoking; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2015
Extended plasma cannabinoid excretion in chronic frequent cannabis smokers during sustained abstinence and correlation with psychomotor performance.
    Drug testing and analysis, 2016, Volume: 8, Issue:7

    Topics: Adolescent; Adult; Aged; Automobile Driving; Cannabis; Dronabinol; Humans; Male; Marijuana Abuse; Marijuana Smoking; Middle Aged; Psychomotor Performance; Psychotropic Drugs; Substance Abuse Detection; Young Adult

2016
Abstinence phenomena of chronic cannabis-addicts prospectively monitored during controlled inpatient detoxification (Part II): Psychiatric complaints and their relation to delta-9-tetrahydrocannabinol and its metabolites in serum.
    Drug and alcohol dependence, 2015, Oct-01, Volume: 155

    Topics: Cannabis; Comorbidity; Dronabinol; Female; Humans; Inpatients; Male; Marijuana Abuse; Mental Disorders; Prospective Studies; Psychiatric Status Rating Scales; Substance Withdrawal Syndrome

2015
Development and validation of an automated liquid-liquid extraction GC/MS method for the determination of THC, 11-OH-THC, and free THC-carboxylic acid (THC-COOH) from blood serum.
    Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:16

    Topics: Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Liquid-Liquid Extraction; Psychotropic Drugs; Serum

2016
An Efficient, Robust Method for the Determination of Cannabinoids in Whole Blood by LC-MS-MS.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:8

    Topics: Analgesics; Calibration; Cannabinoids; Chromatography, Liquid; Dronabinol; Forensic Toxicology; Humans; Limit of Detection; Liquid-Liquid Extraction; Reproducibility of Results; Specimen Handling; Substance Abuse Detection; Tandem Mass Spectrometry

2016
Development of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Simultaneous Determination of Four Cannabinoids in Umbilical Cord Tissue.
    Journal of analytical toxicology, 2018, Jan-01, Volume: 42, Issue:1

    Topics: Biomarkers; Calibration; Cannabinoids; Cannabinol; Chromatography, Liquid; Dronabinol; Enzyme-Linked Immunosorbent Assay; Female; Humans; Limit of Detection; Marijuana Abuse; Marijuana Smoking; Pregnancy; Reference Standards; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Umbilical Cord

2018
Performance and Health-Related Characteristics of Physically Active Males Using Marijuana.
    Journal of strength and conditioning research, 2019, Volume: 33, Issue:6

    Topics: Adult; C-Reactive Protein; Dronabinol; Exercise Test; Forced Expiratory Volume; Humans; Hydrocortisone; Male; Marijuana Smoking; Muscle Strength; Physical Fitness; Testosterone; Young Adult

2019
Proof of active cannabis use comparing 11-hydroxy-∆9-tetrahydrocannabinol with 11-nor-9-carboxy-tetrahydrocannabinol concentrations.
    Drug testing and analysis, 2018, Volume: 10, Issue:10

    Topics: Chromatography, Liquid; Dronabinol; Hair; Humans; Limit of Detection; Marijuana Smoking; Psychotropic Drugs; Substance Abuse Detection; Tandem Mass Spectrometry

2018
A fast and reliable method for quantitation of THC and its 2 main metabolites in whole blood by GC-MS/MS (TQD).
    Forensic science international, 2018, Volume: 289

    Topics: Dronabinol; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Solid Phase Extraction; Substance Abuse Detection

2018