Page last updated: 2024-09-05

11-deoxytetrodotoxin and ouabain

11-deoxytetrodotoxin has been researched along with ouabain in 1 studies

*Ouabain: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE. [MeSH]

*Ouabain: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE. [MeSH]

Compound Research Comparison

Studies
(11-deoxytetrodotoxin)
Trials
(11-deoxytetrodotoxin)
Recent Studies (post-2010)
(11-deoxytetrodotoxin)
Studies
(ouabain)
Trials
(ouabain)
Recent Studies (post-2010) (ouabain)
50116,35772747

Protein Interaction Comparison

ProteinTaxonomy11-deoxytetrodotoxin (IC50)ouabain (IC50)
STAT3, partialHomo sapiens (human)1.154
Kruppel-like factor 5Homo sapiens (human)0.0832
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-1 Rattus norvegicus (Norway rat)4.3
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.17
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.031
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)1.1263
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.1646
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.097
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.8
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Rattus norvegicus (Norway rat)0.0018
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0031

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asai, M; Isobe, M; Nishikawa, T; Urabe, D; Yotsu-Yamashita, M1

Other Studies

1 other study(ies) available for 11-deoxytetrodotoxin and ouabain

ArticleYear
Biological activity of 8,11-dideoxytetrodotoxin: lethality to mice and the inhibitory activity to cytotoxicity of ouabain and veratridine in mouse neuroblastoma cells, Neuro-2a.
    Toxicon : official journal of the International Society on Toxinology, 2003, Volume: 42, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Neuroblastoma; Ouabain; Structure-Activity Relationship; Tetrodotoxin; Veratridine

2003