11-12-15-trihydroxyeicosatrienoic-acid has been researched along with allyl-alcohol* in 1 studies
1 other study(ies) available for 11-12-15-trihydroxyeicosatrienoic-acid and allyl-alcohol
Article | Year |
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Allylic alcohol transposition by ortho ester-initiated carbonate extension. synthesis of the vasodilator 11(R),12(S),15(S)-trihydroxyeicosa- 5(Z),8(Z),13(E)-trienoic acid.
[reaction: see text] The title compound 1 was obtained via methyl ester 2, which was synthesized in four steps from an isomeric 11,14,15-triol ester 5. In the key step, Boc orthoformate 9 was treated with TMS triflate to initiate intramolecular nucleophilic substitution with allylic transposition, forming cyclic carbonates 10 and 11. Topics: 8,11,14-Eicosatrienoic Acid; Carbonates; Catalysis; Esters; Molecular Structure; Propanols; Vasodilator Agents | 2006 |