10-thiirane-4-estrene-3,17-dione and fadrozole

10-thiirane-4-estrene-3,17-dione has been researched along with fadrozole in 2 studies

Compound Research Comparison

Studies (10-thiirane-4-estrene-3,17-dione)	Trials (10-thiirane-4-estrene-3,17-dione)	Recent Studies (post-2010) (10-thiirane-4-estrene-3,17-dione)	Studies (fadrozole)	Trials (fadrozole)	Recent Studies (post-2010) (fadrozole)
7	0	0	443	32	112

Protein Interaction Comparison

Protein	Taxonomy	fadrozole (IC50)
Cytochrome P450 3A4	Homo sapiens (human)	0.0063
Aromatase	Homo sapiens (human)	0.0324
Cytochrome P450 11B1, mitochondrial	Homo sapiens (human)	0.0095
Cytochrome P450 11B2, mitochondrial	Mus musculus (house mouse)	0.19
Cytochrome P450 11B2, mitochondrial	Homo sapiens (human)	0.0045
Cytochrome P450 11B2, mitochondrial	Rattus norvegicus (Norway rat)	0.6

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Batzl, C; Bhatnagar, A; Francotte, E; Furet, P; Lang, M; Rihs, G	1
Hartmann, RW; Le Baut, G; Le Borgne, M; Loge, C; Marchand, P; Palzer, M; Robert, JM	1

Other Studies

2 other study(ies) available for 10-thiirane-4-estrene-3,17-dione and fadrozole

Article	Year
Aromatase inhibitors: synthesis, biological activity, and binding mode of azole-type compounds. Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10 Topics: Aromatase Inhibitors; Azoles; Binding Sites; Chromatography, High Pressure Liquid; Crystallography; Estrenes; Fadrozole; Female; Humans; Models, Molecular; Placenta; Stereoisomerism; Structure-Activity Relationship	1993
Three-dimensional model of cytochrome P450 human aromatase. Journal of enzyme inhibition and medicinal chemistry, 2005, Volume: 20, Issue:6 Topics: Amino Acid Sequence; Animals; Aromatase; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Enzyme Inhibitors; Estrenes; Fadrozole; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Molecular Structure; Rabbits; Sequence Alignment; Structure-Activity Relationship	2005

Article

Year

Aromatase inhibitors: synthesis, biological activity, and binding mode of azole-type compounds.

Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

Topics: Aromatase Inhibitors; Azoles; Binding Sites; Chromatography, High Pressure Liquid; Crystallography; Estrenes; Fadrozole; Female; Humans; Models, Molecular; Placenta; Stereoisomerism; Structure-Activity Relationship

1993

Three-dimensional model of cytochrome P450 human aromatase.

Journal of enzyme inhibition and medicinal chemistry, 2005, Volume: 20, Issue:6

Topics: Amino Acid Sequence; Animals; Aromatase; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Enzyme Inhibitors; Estrenes; Fadrozole; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Molecular Structure; Rabbits; Sequence Alignment; Structure-Activity Relationship

2005