Compounds > 10-propargyl-10-deazaaminopterin
Page last updated: 2024-09-04

10-propargyl-10-deazaaminopterin and zd 6474

10-propargyl-10-deazaaminopterin has been researched along with zd 6474 in 1 studies

Compound Research Comparison

Studies
(10-propargyl-10-deazaaminopterin)		Trials
(10-propargyl-10-deazaaminopterin)		Recent Studies (post-2010)
(10-propargyl-10-deazaaminopterin)		Studies
(zd 6474)		Trials
(zd 6474)		Recent Studies (post-2010) (zd 6474)
119218562388413

Protein Interaction Comparison

ProteinTaxonomy10-propargyl-10-deazaaminopterin (IC50)zd 6474 (IC50)
Tyrosine-protein kinase ABL1Homo sapiens (human)0.1185
Epidermal growth factor receptorHomo sapiens (human)0.5373
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)1.6
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.7738
Platelet-derived growth factor receptor betaHomo sapiens (human)0.7885
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.343
Fibroblast growth factor receptor 1Homo sapiens (human)2.7925
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.0769
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.5812
Kinesin-1 heavy chainHomo sapiens (human)0.4
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.1464
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.5425
Angiopoietin-1 receptorHomo sapiens (human)1.5335
Macrophage-stimulating protein receptorHomo sapiens (human)3.37
Coiled-coil domain-containing protein 6Homo sapiens (human)0.02
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.2

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Chen, XB; Wang, S; Wang, SQ; Yu, B; Yuan, XH; Zhao, W1

Reviews

1 review(s) available for 10-propargyl-10-deazaaminopterin and zd 6474

ArticleYear
FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application.
    European journal of medicinal chemistry, 2021, Mar-15, Volume: 214

    Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Humans; Molecular Structure; Neoplasms; Pyrimidines; United States; United States Food and Drug Administration

2021