10-propargyl-10-deazaaminopterin and vitamin b 12

10-propargyl-10-deazaaminopterin has been researched along with vitamin b 12 in 4 studies

Compound Research Comparison

Studies (10-propargyl-10-deazaaminopterin)	Trials (10-propargyl-10-deazaaminopterin)	Recent Studies (post-2010) (10-propargyl-10-deazaaminopterin)	Studies (vitamin b 12)	Trials (vitamin b 12)	Recent Studies (post-2010) (vitamin b 12)
119	21	85	22,256	1,042	4,803

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	2 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Berthelot, CN; Duvic, M; Jones, D; Leitenberger, JJ; McLaughlin, P; Polder, KD; Pro, B	1
Duffull, SB; Fleisher, M; Hamlin, P; Horwitz, S; Mould, DR; Neylon, E; O'Connor, OA; Saunders, ME; Sirotnak, F; Sweeney, K	1
Azzoli, CG; Dunne, M; Ginsberg, M; Huntington, M; James, L; Kris, MG; Krug, LM; May, J; Miller, V; Patel, JD; Saunders, M; Sirotnak, FM; Subzwari, S; Tyson, L	1
Apollo, A; Cox, L; Fury, MG; Haque, S; Ho, AL; Lipson, BL; Lyo, JK; Pfister, DG; Sales, R; Seetharamu, N; Sherman, EJ; Sima, CS; Xiao, H	1

Trials

2 trial(s) available for 10-propargyl-10-deazaaminopterin and vitamin b 12

Article	Year
Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:11 Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex	2011
A phase II study of pralatrexate with vitamin B12 and folic acid supplementation for previously treated recurrent and/or metastatic head and neck squamous cell cancer. Investigational new drugs, 2014, Volume: 32, Issue:3 Topics: Adult; Aged; Aminopterin; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Vitamin B 12; Vitamin B Complex; Young Adult	2014

Article

Year

Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:11

Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex

2011

A phase II study of pralatrexate with vitamin B12 and folic acid supplementation for previously treated recurrent and/or metastatic head and neck squamous cell cancer.

Investigational new drugs, 2014, Volume: 32, Issue:3

Topics: Adult; Aged; Aminopterin; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Vitamin B 12; Vitamin B Complex; Young Adult

2014

Other Studies

2 other study(ies) available for 10-propargyl-10-deazaaminopterin and vitamin b 12

Article	Year
CD4+ CD56+ hematodermic/plasmacytoid dendritic cell tumor with response to pralatrexate. Journal of the American Academy of Dermatology, 2008, Volume: 58, Issue:3 Topics: Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; CD4 Antigens; CD56 Antigen; Cyclophosphamide; Dendritic Cells; Doxorubicin; Drug Therapy, Combination; Female; Folic Acid; Humans; Killer Cells, Natural; Lymphoma, T-Cell; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prednisone; Skin Neoplasms; Treatment Outcome; Vincristine; Vitamin B 12	2008
A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma. Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:2 Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Area Under Curve; Biomarkers; Body Size; Drug Administration Schedule; Female; Folic Acid Antagonists; Hodgkin Disease; Humans; Incidence; Lymphoma, Non-Hodgkin; Male; Methylmalonic Acid; Middle Aged; Models, Statistical; Mucositis; Predictive Value of Tests; Recurrence; Severity of Illness Index; Vitamin B 12	2009

Article

Year

CD4+ CD56+ hematodermic/plasmacytoid dendritic cell tumor with response to pralatrexate.

Journal of the American Academy of Dermatology, 2008, Volume: 58, Issue:3

Topics: Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; CD4 Antigens; CD56 Antigen; Cyclophosphamide; Dendritic Cells; Doxorubicin; Drug Therapy, Combination; Female; Folic Acid; Humans; Killer Cells, Natural; Lymphoma, T-Cell; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prednisone; Skin Neoplasms; Treatment Outcome; Vincristine; Vitamin B 12

2008

A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma.

Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:2

Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Area Under Curve; Biomarkers; Body Size; Drug Administration Schedule; Female; Folic Acid Antagonists; Hodgkin Disease; Humans; Incidence; Lymphoma, Non-Hodgkin; Male; Methylmalonic Acid; Middle Aged; Models, Statistical; Mucositis; Predictive Value of Tests; Recurrence; Severity of Illness Index; Vitamin B 12

2009