Page last updated: 2024-09-04

10-propargyl-10-deazaaminopterin and thioguanine anhydrous

10-propargyl-10-deazaaminopterin has been researched along with thioguanine anhydrous in 4 studies

Compound Research Comparison

Studies
(10-propargyl-10-deazaaminopterin)
Trials
(10-propargyl-10-deazaaminopterin)
Recent Studies (post-2010)
(10-propargyl-10-deazaaminopterin)
Studies
(thioguanine anhydrous)
Trials
(thioguanine anhydrous)
Recent Studies (post-2010) (thioguanine anhydrous)
11921852,706295389

Protein Interaction Comparison

ProteinTaxonomy10-propargyl-10-deazaaminopterin (IC50)thioguanine anhydrous (IC50)
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.5333
Prostaglandin G/H synthase 1Homo sapiens (human)0.601
Mitogen-activated protein kinase 3 Homo sapiens (human)5.516

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, XB; Wang, S; Wang, SQ; Yu, B; Yuan, XH; Zhao, W1
Bertino, JR; Bhagavathi, S; Chan, WC; Goodell, L; Johnson-Farley, N; Lubin, M1
Bertino, JR; Johnson-Farley, N; Kathari, YK; Tedeschi, PM1

Reviews

2 review(s) available for 10-propargyl-10-deazaaminopterin and thioguanine anhydrous

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application.
    European journal of medicinal chemistry, 2021, Mar-15, Volume: 214

    Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Humans; Molecular Structure; Neoplasms; Pyrimidines; United States; United States Food and Drug Administration

2021

Other Studies

2 other study(ies) available for 10-propargyl-10-deazaaminopterin and thioguanine anhydrous

ArticleYear
Lack of expression of MTAP in uncommon T-cell lymphomas.
    Clinical lymphoma, myeloma & leukemia, 2012, Volume: 12, Issue:5

    Topics: Adenine; Aminopterin; Folic Acid Antagonists; Humans; Lymphoma, T-Cell; Purine-Nucleoside Phosphorylase; Purines; Thioguanine; Tissue Array Analysis

2012
Methylthioadenosine phosphorylase (MTAP)-deficient T-cell ALL xenografts are sensitive to pralatrexate and 6-thioguanine alone and in combination.
    Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:6

    Topics: Aminopterin; Animals; Antineoplastic Agents; Cell Line, Tumor; Heterografts; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Purine-Nucleoside Phosphorylase; Thioguanine

2015