10-propargyl-10-deazaaminopterin has been researched along with probenecid in 2 studies
| Studies (10-propargyl-10-deazaaminopterin) | Trials (10-propargyl-10-deazaaminopterin) | Recent Studies (post-2010) (10-propargyl-10-deazaaminopterin) | Studies (probenecid) | Trials (probenecid) | Recent Studies (post-2010) (probenecid) |
|---|---|---|---|---|---|
| 119 | 21 | 85 | 3,664 | 292 | 375 |
| Protein | Taxonomy | 10-propargyl-10-deazaaminopterin (IC50) | probenecid (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 8 | Mus musculus (house mouse) | 3.02 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 6.85 | |
| Solute carrier family 22 member 8 | Homo sapiens (human) | 6.965 | |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | 6.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Azzoli, CG; Fury, MG; Kemeny, N; Kris, MG; Krug, LM; Rizvi, NA; Sharma, S; Wu, N | 1 |
1 review(s) available for 10-propargyl-10-deazaaminopterin and probenecid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for 10-propargyl-10-deazaaminopterin and probenecid
| Article | Year |
|---|---|
A phase I clinical pharmacologic study of pralatrexate in combination with probenecid in adults with advanced solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Probenecid; Treatment Outcome | 2006 |