Page last updated: 2024-09-04

10-propargyl-10-deazaaminopterin and methylergonovine

10-propargyl-10-deazaaminopterin has been researched along with methylergonovine in 2 studies

Compound Research Comparison

Studies
(10-propargyl-10-deazaaminopterin)
Trials
(10-propargyl-10-deazaaminopterin)
Recent Studies (post-2010)
(10-propargyl-10-deazaaminopterin)
Studies
(methylergonovine)
Trials
(methylergonovine)
Recent Studies (post-2010) (methylergonovine)
11921855274470

Protein Interaction Comparison

ProteinTaxonomy10-propargyl-10-deazaaminopterin (IC50)methylergonovine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.013
Alpha-2A adrenergic receptorHomo sapiens (human)1.59
Cytochrome P450 2D6Homo sapiens (human)0.2
D(2) dopamine receptorHomo sapiens (human)0.829
Alpha-2B adrenergic receptorHomo sapiens (human)0.461
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0041
D(1A) dopamine receptorHomo sapiens (human)1.077
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0025
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.013
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0041
D(3) dopamine receptorHomo sapiens (human)0.167
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0015
5-hydroxytryptamine receptor 6Homo sapiens (human)0.0025

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aalikhani, M; Alikhani, M; Bazi, Z; Oladnabi, M; Shamsabadi, F1

Reviews

1 review(s) available for 10-propargyl-10-deazaaminopterin and methylergonovine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for 10-propargyl-10-deazaaminopterin and methylergonovine

ArticleYear
In silico drug repurposing for the treatment of heart diseases using gene expression data and molecular docking techniques.
    Biochemical and biophysical research communications, 2021, 10-01, Volume: 572

    Topics: Aminoisobutyric Acids; Aminopterin; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Daunorubicin; Digoxin; Drug Repositioning; Gene Expression; Heart Diseases; Humans; Lactams, Macrocyclic; Leucine; Ligands; Methylergonovine; Molecular Docking Simulation; Morpholines; Proline; Quinoxalines; Sulfonamides

2021