10-propargyl-10-deazaaminopterin has been researched along with lometrexol in 1 studies
| Studies (10-propargyl-10-deazaaminopterin) | Trials (10-propargyl-10-deazaaminopterin) | Recent Studies (post-2010) (10-propargyl-10-deazaaminopterin) | Studies (lometrexol) | Trials (lometrexol) | Recent Studies (post-2010) (lometrexol) |
|---|---|---|---|---|---|
| 119 | 21 | 85 | 119 | 7 | 13 |
| Protein | Taxonomy | 10-propargyl-10-deazaaminopterin (IC50) | lometrexol (IC50) |
|---|---|---|---|
| Trifunctional purine biosynthetic protein adenosine-3 | Homo sapiens (human) | 0.0634 | |
| Trifunctional purine biosynthetic protein adenosine-3 | Mus musculus (house mouse) | 0.78 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cherian, C; Gangjee, A; Hou, Z; Matherly, LH; Mitchell-Ryan, S; Orr, S; Raghavan, S; Wang, Y | 1 |
1 other study(ies) available for 10-propargyl-10-deazaaminopterin and lometrexol
| Article | Year |
|---|---|
Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesis.
Topics: Animals; Cell Proliferation; Cells, Cultured; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; Humans; KB Cells; Models, Molecular; Molecular Structure; Purine Nucleotides; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2013 |