Compounds > 10-propargyl-10-deazaaminopterin
Page last updated: 2024-09-04

10-propargyl-10-deazaaminopterin and imatinib

10-propargyl-10-deazaaminopterin has been researched along with imatinib in 1 studies

Compound Research Comparison

Studies
(10-propargyl-10-deazaaminopterin)		Trials
(10-propargyl-10-deazaaminopterin)		Recent Studies (post-2010)
(10-propargyl-10-deazaaminopterin)		Studies
(imatinib)		Trials
(imatinib)		Recent Studies (post-2010) (imatinib)
11921852360157

Protein Interaction Comparison

ProteinTaxonomy10-propargyl-10-deazaaminopterin (IC50)imatinib (IC50)
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABLMus musculus (house mouse)0.1
Aurora kinase AHomo sapiens (human)4.3
Solute carrier family 22 member 2Homo sapiens (human)4.2
Bile salt export pumpHomo sapiens (human)10
Tyrosine-protein kinase ABL1Homo sapiens (human)0.6804
Tyrosine-protein kinase ABL1Mus musculus (house mouse)0.3704
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)2.784
Epidermal growth factor receptorHomo sapiens (human)0.0001
Carbonic anhydrase 2Homo sapiens (human)0.372
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0001
Platelet-derived growth factor receptor betaMus musculus (house mouse)0.3
Tyrosine-protein kinase LckHomo sapiens (human)0.2667
Cyclin-dependent kinase 1Homo sapiens (human)4.3
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.8417
Tyrosine-protein kinase LynHomo sapiens (human)0.22
ATP-dependent translocase ABCB1Homo sapiens (human)5.0229
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.4
Hepatocyte growth factor receptorHomo sapiens (human)0.0216
Platelet-derived growth factor receptor betaHomo sapiens (human)0.285
Dihydrofolate reductaseEscherichia coli K-120.372
Mast/stem cell growth factor receptor KitHomo sapiens (human)1.2682
Breakpoint cluster region proteinHomo sapiens (human)0.5032
Solute carrier family 2, facilitated glucose transporter member 4Mus musculus (house mouse)0.473
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)5
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.175
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.1516
Thromboxane-A synthase Homo sapiens (human)0.198
Cyclin-dependent kinase 2Homo sapiens (human)3.318
Histamine H2 receptorHomo sapiens (human)1.963
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)0.3
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.891
Sodium-dependent serotonin transporterHomo sapiens (human)1.402
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.131
Tyrosine-protein kinase ABL2Homo sapiens (human)0.156
Tyrosine-protein kinase SYKHomo sapiens (human)5
Serine/threonine-protein kinase PLK1Homo sapiens (human)4.3
Platelet-derived growth factor receptor betaRattus norvegicus (Norway rat)0.162
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)0.2964
Discoidin domain-containing receptor 2Homo sapiens (human)0.457
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)8.3
Multidrug and toxin extrusion protein 2Homo sapiens (human)1.625
Multidrug and toxin extrusion protein 1Homo sapiens (human)0.1467
Aurora kinase BHomo sapiens (human)4.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2.9096
Aurora kinase CHomo sapiens (human)4.3

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for 10-propargyl-10-deazaaminopterin and imatinib

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016