10-propargyl-10-deazaaminopterin has been researched along with gemcitabine in 8 studies
| Studies (10-propargyl-10-deazaaminopterin) | Trials (10-propargyl-10-deazaaminopterin) | Recent Studies (post-2010) (10-propargyl-10-deazaaminopterin) | Studies (gemcitabine) | Trials (gemcitabine) | Recent Studies (post-2010) (gemcitabine) |
|---|---|---|---|---|---|
| 119 | 21 | 85 | 12,523 | 3,208 | 6,923 |
| Protein | Taxonomy | 10-propargyl-10-deazaaminopterin (IC50) | gemcitabine (IC50) |
|---|---|---|---|
| Chain A, DEOXYNUCLEOSIDE KINASE | Drosophila melanogaster (fruit fly) | 0.76 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 0.19 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gardner, J; Gonen, M; Heaney, M; O'Connor, OA; Sirotnak, F; Smith, EA; Teruya-Feldstein, J; Toner, LE; Vrhovac, R | 1 |
| O'Leary, HM; Savage, KJ | 1 |
| Mangone, M; Marchi, E; O'Connor, OA; Zullo, K | 1 |
| Duvic, M | 1 |
| Beltran, BE; Conlon, K; Cook, L; Dwyer, K; Feldman, T; Fields, PA; Gonsky, J; Hermine, O; Horwitz, SM; Humphrey, J; Kurman, M; Leoni, M; Moriya, J; Pereira, J; Phillips, AA; Ramos, JC; Sawas, A; Taylor, GP; Wandroo, F | 1 |
| Desai, N; Goff, HW; Rizvi, S; Stewart, JR; Zhu, H | 1 |
| Kaur, H; Lee, YS; Ong, SY; Phipps, C; Tan, L | 1 |
3 review(s) available for 10-propargyl-10-deazaaminopterin and gemcitabine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Novel therapies in peripheral T-cell lymphomas.
Topics: Alemtuzumab; Aminopterin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxycytidine; Diphtheria Toxin; Enzyme Inhibitors; Gemcitabine; Humans; Immunotherapy; Interleukin-2; Lymphoma, T-Cell, Peripheral; Medical Oncology; Prognosis; Recombinant Fusion Proteins; Treatment Outcome | 2008 |
Alemtuzumab is an effective third-line treatment versus single-agent gemcitabine or pralatrexate for refractory Sézary syndrome: a systematic review.
Topics: Alemtuzumab; Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Agents, Immunological; Deoxycytidine; Folic Acid Antagonists; Gemcitabine; Humans; Mycosis Fungoides; Retreatment; Sezary Syndrome; Skin Neoplasms | 2018 |
2 trial(s) available for 10-propargyl-10-deazaaminopterin and gemcitabine
| Article | Year |
|---|---|
Pralatrexate pharmacology and clinical development.
Topics: Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Deoxycytidine; Depsipeptides; Disease-Free Survival; Drug Approval; Drug Synergism; Gemcitabine; Humans; Lymphoma, T-Cell; Male; Pyrazines; Treatment Outcome; United States; United States Food and Drug Administration | 2013 |
Mogamulizumab
Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Deoxycytidine; Dexamethasone; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gemcitabine; Humans; International Agencies; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Neoplasm Recurrence, Local; Oxaliplatin; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate; Young Adult | 2019 |
3 other study(ies) available for 10-propargyl-10-deazaaminopterin and gemcitabine
| Article | Year |
|---|---|
The schedule-dependent effects of the novel antifolate pralatrexate and gemcitabine are superior to methotrexate and cytarabine in models of human non-Hodgkin's lymphoma.
Topics: Aminopterin; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cytarabine; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Gemcitabine; Humans; In Vitro Techniques; Lymphoma, Non-Hodgkin; Methotrexate; Mice; Mice, SCID; Time Factors; Xenograft Model Antitumor Assays | 2006 |
Choosing a systemic treatment for advanced stage cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome.
Topics: Alemtuzumab; Aminopterin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Clinical Trials as Topic; Deoxycytidine; Depsipeptides; Diphtheria Toxin; Disease Progression; Doxorubicin; Electrons; Gemcitabine; Humans; Hydroxamic Acids; Immunotherapy; Incidence; Interleukin-2; Lenalidomide; Lymphoma, T-Cell; Mycosis Fungoides; Pentostatin; Photopheresis; Polyethylene Glycols; Randomized Controlled Trials as Topic; Recombinant Fusion Proteins; Retinoids; Sezary Syndrome; Stem Cell Transplantation; Thalidomide; United States; Vorinostat | 2015 |
Pralatrexate Induces Long-Term Remission in Relapsed Subcutaneous Panniculitis-Like T-Cell Lymphoma.
Topics: Adult; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cisplatin; Cyclophosphamide; Deoxycytidine; Dexamethasone; Doxorubicin; Folic Acid Antagonists; Gemcitabine; Humans; Lymphohistiocytosis, Hemophagocytic; Lymphoma, T-Cell, Peripheral; Male; Neoplasm Recurrence, Local; Panniculitis; Prednisone; Remission Induction; Subcutaneous Fat, Abdominal; Vincristine | 2019 |