Page last updated: 2024-09-04

10-propargyl-10-deazaaminopterin and etoposide

10-propargyl-10-deazaaminopterin has been researched along with etoposide in 3 studies

Compound Research Comparison

Studies
(10-propargyl-10-deazaaminopterin)
Trials
(10-propargyl-10-deazaaminopterin)
Recent Studies (post-2010)
(10-propargyl-10-deazaaminopterin)
Studies
(etoposide)
Trials
(etoposide)
Recent Studies (post-2010) (etoposide)
119218518,3063,6934,900

Protein Interaction Comparison

ProteinTaxonomy10-propargyl-10-deazaaminopterin (IC50)etoposide (IC50)
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]Homo sapiens (human)1.153
nuclear receptor coactivator 3 isoform aHomo sapiens (human)1.4284
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)3.187
Caspase-3Homo sapiens (human)1
DNA topoisomerase 2-betaHomo sapiens (human)0.4299
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)4.18

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Grossman, ME; Husain, S; MacGregor-Cortelli, B; Marneros, AG; Neylon, E; Nuovo, GJ; O'Connor, OA; Patterson, M; Silvers, DN; Zain, JM1

Reviews

1 review(s) available for 10-propargyl-10-deazaaminopterin and etoposide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for 10-propargyl-10-deazaaminopterin and etoposide

ArticleYear
A phase II study of cyclophosphamide, etoposide, vincristine and prednisone (CEOP) alternating with pralatrexate (P) as front line therapy for patients with peripheral T-cell lymphoma (PTCL): preliminary results from the T-Cell Consortium trial.
    Clinical advances in hematology & oncology : H&O, 2014, Volume: 12, Issue:2 Suppl 5

    Topics: Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide; Female; Humans; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Prednisone; Vincristine

2014

Other Studies

1 other study(ies) available for 10-propargyl-10-deazaaminopterin and etoposide

ArticleYear
Pralatrexate-induced tumor cell apoptosis in the epidermis of a patient with HTLV-1 adult T-cell lymphoma/leukemia causing skin erosions.
    Blood, 2009, Jun-18, Volume: 113, Issue:25

    Topics: Adult; Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biopsy; Cyclophosphamide; Diagnosis, Differential; Disease Progression; Doxorubicin; Drug Eruptions; Epidermis; Etoposide; Exanthema; Folic Acid Antagonists; Humans; Interferon alpha-2; Interferon-alpha; Leukemia-Lymphoma, Adult T-Cell; Male; Prednisone; Recombinant Proteins; Vincristine; Zidovudine

2009