Page last updated: 2024-09-02

10-hydroxycarbamazepine and eslicarbazepine

10-hydroxycarbamazepine has been researched along with eslicarbazepine in 5 studies

Compound Research Comparison

Studies
(10-hydroxycarbamazepine)
Trials
(10-hydroxycarbamazepine)
Recent Studies (post-2010)
(10-hydroxycarbamazepine)
Studies
(eslicarbazepine)
Trials
(eslicarbazepine)
Recent Studies (post-2010) (eslicarbazepine)
106203042340

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Alves, PC; Benes, J; Cunha, RA; Figueiredo, AA; Freitas, AP; Garrett, J; Learmonth, DA; Parada, A; Soares-da-Silva, P1
Czendlik, C; Flesch, G; Lloyd, P; Renard, D1
Almeida, A; Alves, G; Falcão, A; Fortuna, A; Lopes, B; Soares-da-Silva, P1
Crommen, J; Fillet, M; Janicot, B; Servais, AC; Takam, A1
Bayraktar, E; Eltokhi, A; Hedrich, UBS; Lauxmann, S; Lerche, H; Liu, Y; Lyu, H; Sara, Y; Sonnenberg, L; Wuttke, TV1

Trials

1 trial(s) available for 10-hydroxycarbamazepine and eslicarbazepine

ArticleYear
Pharmacokinetics of the monohydroxy derivative of oxcarbazepine and its enantiomers after a single intravenous dose given as racemate compared with a single oral dose of oxcarbazepine.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:6

    Topics: Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Molecular Structure; Reproducibility of Results; Stereoisomerism; Tissue Distribution

2011

Other Studies

4 other study(ies) available for 10-hydroxycarbamazepine and eslicarbazepine

ArticleYear
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.
    Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14

    Topics: Amides; Animals; Anticonvulsants; Azepines; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Electroshock; In Vitro Techniques; Ion Channel Gating; Motor Activity; Prodrugs; Rats; Seizures; Sodium; Stereoisomerism; Structure-Activity Relationship; Synaptosomes

1999
A chiral liquid chromatography method for the simultaneous determination of oxcarbazepine, eslicarbazepine, R-licarbazepine and other new chemical derivatives BIA 2-024, BIA 2-059 and BIA 2-265, in mouse plasma and brain.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Calibration; Carbamazepine; Chromatography, Liquid; Dibenzazepines; Mice; Oxcarbazepine; Quality Control; Reference Standards; Spectrophotometry, Ultraviolet; Stereoisomerism

2012
Liquid chromatography separation of the chiral prodrug eslicarbazepine acetate and its main metabolites in polar organic mode. Application to their analysis after in vitro metabolism.
    Journal of chromatography. A, 2016, Oct-07, Volume: 1467

    Topics: Acetic Acid; Acetonitriles; Carbamazepine; Cellulose; Chromatography, Liquid; Dibenzazepines; Diethylamines; Humans; Microsomes, Liver; Oxcarbazepine; Phenylcarbamates; Prodrugs; Solid Phase Extraction; Solvents; Stereoisomerism

2016
In vitro effects of eslicarbazepine (S-licarbazepine) as a potential precision therapy on SCN8A variants causing neuropsychiatric disorders.
    British journal of pharmacology, 2023, Volume: 180, Issue:8

    Topics: Animals; Dibenzazepines; Epilepsy; Mice; Mutation; NAV1.6 Voltage-Gated Sodium Channel

2023