10-formyldihydropteroylglutamate has been researched along with 4-aminobenzoylglutamic-acid* in 1 studies
1 other study(ies) available for 10-formyldihydropteroylglutamate and 4-aminobenzoylglutamic-acid
| Article | Year |
|---|---|
A thin-layer chromatographic method to determine process impurities in leucovorin calcium.
A densitometric thin-layer chromatographic method for the analysis of process impurities in leucovorin calcium was developed and validated. Using this method, folic acid, N10-formyldihydrofolic acid, p-aminobenzoic acid, and N-(4-aminobenzoyl)-L-glutamic acid were monitored with a limit of detection of approximately 0.1% each. Both absorbance and fluorescence densitometric evaluations were utilized; fluorescence evaluation selectively detected impurities that were not chromatographically resolved from leucovorin. Topics: 4-Aminobenzoic Acid; Chemistry, Pharmaceutical; Chromatography, Thin Layer; Densitometry; Folic Acid; Glutamates; Leucovorin; Light; Reproducibility of Results | 1992 |