10-deazaaminopterin has been researched along with folic acid in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DeGraw, JI; Dorick, DM; Moccio, DM; Sirotnak, FM | 1 |
| Alarcón, GS; Castañeda, O; Ferrándiz, M; Koopman, WJ; Krumdieck, CL | 1 |
| McCord, JM; Nair, MG; Weber, GF | 1 |
| Baugh, CM; Gaumont, Y; Kaufman, BT; Kisliuk, RL; Kumar, P; Nair, MG | 1 |
| Moccio, DM; Samuels, LL; Sirotnak, FM | 1 |
1 trial(s) available for 10-deazaaminopterin and folic acid
| Article | Year |
|---|---|
Efficacy and safety of 10-deazaaminopterin in the treatment of rheumatoid arthritis. A one-year continuation, double-blind study.
Topics: Adult; Alkaline Phosphatase; Aminopterin; Arthritis, Rheumatoid; Aspartate Aminotransferases; Double-Blind Method; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged | 1992 |
4 other study(ies) available for 10-deazaaminopterin and folic acid
| Article | Year |
|---|---|
Antitumor properties of a new folate analog, 10-deaza-aminopterin, in mice.
Topics: Aminopterin; Animals; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinical; Female; Folic Acid; Leukemia L1210; Liver Neoplasms; Male; Methotrexate; Mice; Neoplasms, Experimental; Plasmacytoma; Sarcoma 180 | 1978 |
The antifolate 10-deazaaminopterin inhibits neutrophil chemotaxis and superoxide generation.
Topics: Adult; Aminopterin; Cell Degranulation; Cells, Cultured; Chemotaxis, Leukocyte; Female; Folic Acid; Folic Acid Antagonists; Humans; Male; Methotrexate; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Superoxides | 1991 |
Interaction of polyglutamyl derivatives of methotrexate, 10-deazaaminopterin, and dihydrofolate with dihydrofolate reductase.
Topics: Aminopterin; Animals; Cattle; Chickens; Folic Acid; Folic Acid Antagonists; Methotrexate; Peptides; Polyglutamic Acid; Potassium Chloride; Sheep; Structure-Activity Relationship | 1986 |
Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
Topics: Aminopterin; Animals; Cells, Cultured; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Neoplasms; Pteroylpolyglutamic Acids; Tumor Stem Cell Assay | 1985 |