10-deacetyltaxol has been researched along with paclitaxel in 17 studies
| Studies (10-deacetyltaxol) | Trials (10-deacetyltaxol) | Recent Studies (post-2010) (10-deacetyltaxol) | Studies (paclitaxel) | Trials (paclitaxel) | Recent Studies (post-2010) (paclitaxel) |
|---|---|---|---|---|---|
| 23 | 0 | 11 | 31,874 | 5,729 | 15,395 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Guénard, D; Guéritte-Voegelein, F; Lavelle, F; Le Goff, MT; Mangatal, L; Potier, P | 1 |
| Kobayashi, J; Shigemori, H | 1 |
| Audus, KL; Datta, A; Desino, K; Dutta, D; Georg, GI; Himes, RH; Huff, JK; Rice, A; Seelig, A; Spletstoser, JT; Turunen, BJ | 1 |
| Ballatore, C; Deiches, RF; Huryn, D; Hyde, E; Lee, VM; Smith, AB; Trojanowski, JQ | 1 |
| Awale, S; Dang, PH; Duong, TTT; Nguyen, HX; Nguyen, MTT; Nguyen, NT; Nguyen, PT; Phan, NHT; Tran, TKT; Vu, TKT; Vuong, HC | 1 |
| Horwitz, SB; Ringel, I | 1 |
| Bhakuni, RS; Johnson, J; Oruganti, RS; Rao, KV | 1 |
| Tabancay, AP; Wang, CJ; Woo, DD | 1 |
| Alvinerie, P; Cresteil, T; Dubois, J; Gueritte, F; Monsarrat, B; Sonnier, M | 1 |
| Hanson, RL; Parker, WL; Patel, RN | 1 |
| Du, X; Ge, G; Hou, K; Liu, X; Luan, H; Yang, L | 1 |
| Bai, X; Gou, X; Hou, X; Huang, M; Jin, J; Li, D; Liu, B; Zhong, G | 1 |
| Liu, WC; Zhu, P | 1 |
| Bonfill, M; Cusido, RM; Moyano, E; Osuna, L; Palazon, J; Ramirez-Estrada, K; Tapia, N | 1 |
| Dong, M; Guo, H; Pi, E; Shen, C; Song, Y; Wang, H; Yu, C; Zhang, L; Zhang, Y; Zheng, B | 1 |
| Gao, JM; Li, J; Shi, YQ; Zhang, CY; Zhang, QM | 1 |
| Chen, JJ; Chen, TJ; Gong, W; Li, L; Liu, WC; Si, YK; Wang, F; Yang, L; Yu, WB; Zhu, P | 1 |
1 review(s) available for 10-deacetyltaxol and paclitaxel
| Article | Year |
|---|---|
Biological activity and chemistry of taxoids from the Japanese yew, Taxus cuspidata.
Topics: Antineoplastic Agents, Phytogenic; Molecular Structure; Paclitaxel; Plants, Medicinal; Stereoisomerism; Structure-Activity Relationship; Taxoids; Taxus | 2004 |
16 other study(ies) available for 10-deacetyltaxol and paclitaxel
| Article | Year |
|---|---|
Relationships between the structure of taxol analogues and their antimitotic activity.
Topics: Alkaloids; Animals; Antineoplastic Agents; Brain; Cell Division; Chemical Phenomena; Chemistry; Leukemia P388; Mice; Microtubules; Molecular Conformation; Molecular Structure; Paclitaxel; Stereoisomerism; Structure-Activity Relationship; Swine; Tubulin | 1991 |
Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells.
Topics: Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Cattle; Drug Interactions; Endothelial Cells; Female; Microcirculation; Paclitaxel; Permeability; Rhodamines; Taxoids | 2006 |
Paclitaxel C-10 carbamates: potential candidates for the treatment of neurodegenerative tauopathies.
Topics: Animals; Blood-Brain Barrier; Brain; Carbamates; Chemistry, Pharmaceutical; Drug Design; Humans; Mice; Models, Chemical; Neurodegenerative Diseases; Paclitaxel; Permeability; Tauopathies; Time Factors | 2007 |
α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana.
Topics: alpha-Glucosidases; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Diterpenes; Glycoside Hydrolase Inhibitors; Humans; Molecular Structure; Paclitaxel; Plant Bark; Taxoids; Taxus | 2017 |
Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium.
Topics: Alkaloids; Animals; Cell Division; Cells, Cultured; Chemical Phenomena; Chemistry; Culture Media; Drug Stability; Hydrolysis; Isomerism; Microtubules; Paclitaxel; Taxoids | 1987 |
Synthesis and evaluation of some 10-mono- and 2',10-diesters of 10-deacetylpaclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Esters; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Paclitaxel; Taxoids; Tumor Cells, Cultured | 1995 |
Microtubule active taxanes inhibit polycystic kidney disease progression in cpk mice.
Topics: Alkaloids; Animals; Kidney; Mice; Mice, Inbred C57BL; Microtubules; Paclitaxel; Polycystic Kidney Diseases; Structure-Activity Relationship; Taxoids | 1997 |
Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship.
Topics: Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; COS Cells; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Docetaxel; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Paclitaxel; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Taxoids; Triterpenes | 2002 |
Enzymatic C-4 deacetylation of 10-deacetylbaccatin III.
Topics: Acetylation; Alkaloids; Aminohydrolases; Antineoplastic Agents, Phytogenic; Bacterial Proteins; Paclitaxel; Rhodococcus; Soil Microbiology; Stenotrophomonas maltophilia; Taxoids | 2006 |
[Industrial preparative chromatography purification of 10-deacetylpaclitaxel, the enzymatic product of 7-xylosyl-10-deacetylpaclitaxel].
Topics: Chromatography, High Pressure Liquid; Paclitaxel; Taxoids | 2012 |
Simultaneous determination of seven taxoids in rat plasma by UPLC-MS/MS and pharmacokinetic study after oral administration of Taxus yunnanensis extracts.
Topics: Administration, Oral; Alkaloids; Animals; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Docetaxel; Male; Methyl Ethers; Paclitaxel; Plant Extracts; Plasma; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Taxoids; Taxus | 2015 |
Pilot studies on scale-up biocatalysis of 7-β-xylosyl-10-deacetyltaxol and its analogues by an engineered yeast.
Topics: Biocatalysis; Biotransformation; Fermentation; Glycoside Hydrolases; Paclitaxel; Pichia; Pilot Projects; Shiitake Mushrooms; Taxoids | 2015 |
Changes in gene transcription and taxane production in elicited cell cultures of Taxus × media and Taxus globosa.
Topics: Alkaloids; Amino Acids; Bridged-Ring Compounds; Cell Culture Techniques; Cyclodextrins; Indenes; Paclitaxel; Taxoids; Taxus; Transcription, Genetic | 2015 |
Identification of potential genes that contributed to the variation in the taxoid contents between two Taxus species (Taxus media and Taxus mairei).
Topics: Chromatography, High Pressure Liquid; Gene Expression Profiling; Paclitaxel; Tandem Mass Spectrometry; Taxoids; Taxus; Transcriptome | 2017 |
[The impurity profiling of paclitaxel and its injection by UPLC-MS/MS].
Topics: Alkaloids; China; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Contamination; Injections; Paclitaxel; Tandem Mass Spectrometry; Taxoids | 2016 |
Structures of β-glycosidase LXYL-P1-2 reveals the product binding state of GH3 family and a specific pocket for Taxol recognition.
Topics: Amino Acid Sequence; Catalysis; Catalytic Domain; Glucosidases; Models, Molecular; Molecular Conformation; Mutation; Paclitaxel; Polysaccharides; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Taxoids | 2020 |