10-deacetylbaccatine iii has been researched along with paclitaxel in 44 studies
| Studies (10-deacetylbaccatine iii) | Trials (10-deacetylbaccatine iii) | Recent Studies (post-2010) (10-deacetylbaccatine iii) | Studies (paclitaxel) | Trials (paclitaxel) | Recent Studies (post-2010) (paclitaxel) |
|---|---|---|---|---|---|
| 77 | 0 | 26 | 31,874 | 5,729 | 15,395 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.27) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 20 (45.45) | 29.6817 |
| 2010's | 12 (27.27) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, YT; Cheng, KC; Cheng, YB; Chien, CT; Guh, JH; Khalil, AT; Lin, YC; Shen, YC; Teng, CM | 1 |
| Abe, M; Ando, M; Bai, J; Hasegawa, T; Hirose, K; Kawakami, J; Kikuchi, M; Matsubara, J; Sakai, J; Tomida, A; Tsuruo, T; Wang, J; Zhang, S | 1 |
| Bu, XZ; Chen, Y; Guo, YQ; Jin, J; Qiu, J; Sun, ZH; Tang, GH; Yin, S; Zhu, CG | 1 |
| Guénard, D; Lataste, H; Potier, P; Senilh, V; Wright, M | 1 |
| Kirikae, F; Kirikae, T; Morrison, DC; Nakano, M; Qureshi, N; Takayama, K | 1 |
| Bignami, GS; Byrnes, JB; Grothaus, PG; Lazo, CB; Raybould, TJ | 1 |
| Ewald, D; Hacker, C; Hornbogen, T; Kammer, B; Weckwerth, W; Zocher, R | 1 |
| Bombardelli, E; De Vincenzo, R; Distefano, M; Fattorossi, A; Ferlini, C; Gaggini, C; Mancuso, S; Ojima, I; Panici, PB; Riva, A; Scambia, G | 1 |
| Ishiyama, T; Soga, T; Takenoshita, H; Terasawa, H; Uoto, K | 1 |
| Barthol, A; Croteau, R; Gatfield, D; Goleniowski, M; Hezari, M; Ketchum, RE; Walker, K | 1 |
| Glowniak, K; Mroczek, T; Zobel, AM | 1 |
| Abela, BA; Mulchandani, A; Sheikh, SH | 1 |
| Głowniak, K; Hajnos, ML; Zobel, AM | 1 |
| Glowniak, K; Mroczek, T | 1 |
| Alvinerie, P; Cresteil, T; Dubois, J; Gueritte, F; Monsarrat, B; Sonnier, M | 1 |
| Canaguier, A; Chriqui, D; Hocquemiller, R; Landré, P; Meyer, M; Parc, G | 1 |
| Chen, Y; Hu, Q; Wu, Y; Zhu, W | 1 |
| Cazemier, G; de Jong, GJ; Diallo, B; Haasnoot, W; Jaziri, M; Papadoyannis, IN; Schilt, R; Theodoridis, G | 1 |
| Dai, J; Guo, D; Guo, H; Hu, Q; Ye, M; Zhang, D; Zheng, J; Zhu, W | 1 |
| Baldelli, E; Battaglia, A; Bombardelli, E; Carenzi, G; Fontana, G; Gambini, A; Gelmi, ML; Guerrini, A; Pocar, D | 1 |
| Furmanowa, M; Syklowska-Baranek, K | 1 |
| Loncaric, C; Merriweather, E; Walker, KD | 1 |
| Hanson, RL; Parker, WL; Patel, RN | 1 |
| Fu, Y; Li, Q; Li, S; Schwarz, G; Sun, R; Zu, Y | 1 |
| Stella, VJ; Tian, J | 1 |
| Chen, X; Dai, J; Li, J; Zhu, P | 1 |
| Armirotti, A; Balbi, A; Bestoso, F; Damonte, G; Mazzei, M; Miele, M; Ottaggio, L; Sancandi, M | 1 |
| Ahmad, A; Ahmed, N; Dasari, S; Islam Khan, M; Krishnasastry, MV; Sneh, A; Srivastava, SS | 1 |
| Fu, K; Fu, Y; Li, S; Li, Z; Luo, H; Luo, M; Sun, R; Wang, Y; Zu, Y | 1 |
| Ahmad, A; Khan, I; Santhakumari, B; Sarkar, D; Sarkar, S; Sreekanth, D; Syed, A | 1 |
| Bonfill, M; Cusidó, RM; Goossens, A; Moyano, E; Onrubia, M; Palazón, J | 1 |
| Bonfill, M; Farzaneh, M; Ghassempour, A; Mirjalili, MH; Rezadoost, H | 1 |
| Abdolmaleki, P; Ghanati, F; Hajnoruzi, A; Mokhtari-Dizaji, M; Rezaei, A; Safari, M | 1 |
| Fu, C; Li, S; Yu, L; Zhang, M; Zhang, P | 1 |
| Nicolaou, KC; Valiulin, RA | 1 |
| Guo, LQ; Han, F; Kang, LZ; Lin, JF; Ye, ZW; Zeng, XL | 1 |
| Bai, X; Gou, X; Hou, X; Huang, M; Jin, J; Li, D; Liu, B; Zhong, G | 1 |
| Bai, XY; Jiang, RW; Lü, JM; Zhang, W; Zhou, YY; Zhu, ZR | 1 |
| Chen, JJ; Chen, TJ; Gong, T; Li, BJ; Wang, H; Yang, JL; Zhu, P | 1 |
| Guo, LQ; Huang, JJ; Lin, JF; Lin, SL; Ouyang, PL; Wei, JB; Wei, T; Wu, GP | 1 |
| Jayabaskaran, C; Sah, B; Subban, K | 1 |
| Guo, LQ; Han, PY; Han, WF; Huang, JJ; Lin, JF; Wei, T; Ye, AQ | 1 |
| Chakravarthi, BVSK; Gupta, VK; Jayabaskaran, C; Kamalraj, S; Singh, S | 1 |
| Ahmad, S; Amin, S; Mir, SR; Nurullah, M; Panda, BP; Usmani, Z | 1 |
44 other study(ies) available for 10-deacetylbaccatine iii and paclitaxel
| Article | Year |
|---|---|
Three new taxane diterpenoids from Taxus sumatrana.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Taiwan; Taxoids; Taxus; Tumor Cells, Cultured | 2005 |
Structure-activity relationships of some taxoids as multidrug resistance modulator.
Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Structure-Activity Relationship; Taxoids; Taxus | 2007 |
Isolation and cytotoxicity evaluation of taxanes from the barks of Taxus wallichiana var. mairei.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Mice; Molecular Conformation; NIH 3T3 Cells; Paclitaxel; Plant Bark; Structure-Activity Relationship; Taxoids; Taxus | 2015 |
Relationships between the structures of taxol and baccatine III derivatives and their in vitro action on the disassembly of mammalian brain and Physarum amoebal microtubules.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Brain; Macromolecular Substances; Microtubules; Paclitaxel; Physarum; Species Specificity; Structure-Activity Relationship; Swine; Taxoids; Triterpenes; Tubulin | 1984 |
CD14 is not involved in Rhodobacter sphaeroides diphosphoryl lipid A inhibition of tumor necrosis factor alpha and nitric oxide induction by taxol in murine macrophages.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Binding Sites; Colchicine; Female; Lipid A; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Nitric Oxide; Paclitaxel; Polymyxin B; Rhodobacter sphaeroides; Taxoids; Triterpenes; Tumor Necrosis Factor-alpha; Vinblastine; Zymosan | 1995 |
An enzyme immunoassay for the determination of taxol and taxanes in Taxus sp. tissues and human plasma.
Topics: Alkaloids; Animals; Antibody Specificity; Female; Hemocyanins; Humans; Immunoenzyme Techniques; Paclitaxel; Rabbits; Taxoids; Trees; Triterpenes | 1993 |
Biosynthesis of taxol: enzymatic acetylation of 10-deacetylbaccatin-III to baccatin-III in crude extracts from roots of Taxus baccata.
Topics: Acetylation; Alkaloids; Antineoplastic Agents, Phytogenic; Cell-Free System; Chromatography, High Pressure Liquid; Paclitaxel; Plant Roots; Plants, Medicinal; Taxoids; Triterpenes | 1996 |
Anti-proliferative activity of a new class of taxanes (14beta-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Humans; Leukemia; Mitosis; Paclitaxel; Structure-Activity Relationship; Taxoids; Triterpenes; Tumor Cells, Cultured | 1997 |
A new method to modify the C-4 position of 10-deacetylbaccatin III.
Topics: Alkylation; Paclitaxel; Spectrophotometry, Infrared; Taxoids; Triterpenes | 1997 |
Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis.
Topics: Acetyltransferases; Acylation; Alkaloids; Kinetics; Paclitaxel; Plants, Medicinal; Substrate Specificity; Taxoids; Time Factors; Triterpenes | 1999 |
Seasonal changes in the concentrations of four taxoids in Taxus baccata L. during the autumn-spring period.
Topics: Alkaloids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Molecular Structure; Paclitaxel; Seasons; Taxoids; Trees; Triterpenes | 1999 |
Development of a fluorescence immunoassay for measurement of paclitaxel in human plasma.
Topics: Alkaloids; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Immunoassay; Immunoglobulin G; Paclitaxel; Reproducibility of Results; Rhodamines; Spectrometry, Fluorescence; Staphylococcal Protein A; Taxoids; Time Factors; Triterpenes | 2000 |
The influence of ultraviolet radiation on the content of pharmacologically active taxoids in yew tissues.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diterpenes; Paclitaxel; Plant Extracts; Plant Shoots; Plants, Medicinal; Taxoids; Taxus; Triterpenes; Ultraviolet Rays | 2001 |
Solid-phase extraction and simplified high-performance liquid chromatographic determination of 10-deacetylbaccatin III and related taxoids in yew species.
Topics: Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Paclitaxel; Plant Extracts; Plants, Medicinal; Silica Gel; Silicon Dioxide; Taxoids; Taxus; Terpenes; Triterpenes | 2001 |
Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship.
Topics: Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; COS Cells; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Docetaxel; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Paclitaxel; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Taxoids; Triterpenes | 2002 |
Production of taxoids with biological activity by plants and callus culture from selected Taxus genotypes.
Topics: Antineoplastic Agents, Phytogenic; Culture Techniques; Genotype; Humans; KB Cells; Paclitaxel; Plant Leaves; Taxoids; Taxus; Toxicity Tests; Triterpenes | 2002 |
[Effects of phenylalanine, sucrose and mannitol on the growth and production of taxol, baccatin III and 10-deacetylbaccatin III in suspension cells of Taxus media].
Topics: Alkaloids; Cell Division; Cells, Cultured; Mannitol; Paclitaxel; Phenylalanine; Sucrose; Taxoids; Taxus; Triterpenes | 1998 |
Immunoaffinity chromatography for the sample pretreatment of Taxus plant and cell extracts prior to analysis of taxanes by high-performance liquid chromatography.
Topics: Antibodies; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cells, Cultured; Chromatography, Affinity; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Immunochemistry; Immunoconjugates; Immunoglobulin G; Ovalbumin; Paclitaxel; Plant Extracts; Sepharose; Serum Albumin, Bovine; Solvents; Spectrophotometry, Ultraviolet; Taxoids; Taxus; Triterpenes | 2002 |
Substrate specificity for the hydroxylation of polyoxygenated 4(20),11-taxadienes by Ginkgo cell suspension cultures.
Topics: Alkenes; Biotransformation; Bridged-Ring Compounds; Cells, Cultured; Diterpenes; Ginkgo biloba; Hydroxylation; Molecular Structure; Paclitaxel; Plants, Medicinal; Substrate Specificity; Taxoids | 2003 |
Diastereoselective 14beta-hydroxylation of baccatin III derivatives.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Docetaxel; Hydroxylation; Molecular Structure; Oxidation-Reduction; Paclitaxel; Stereoisomerism; Taxoids | 2003 |
Taxane production in suspension culture of Taxus x media var. Hicksii carried out in flasks and bioreactor.
Topics: Bioreactors; Bridged-Ring Compounds; Paclitaxel; Taxoids; Taxus | 2005 |
Profiling a Taxol pathway 10beta-acetyltransferase: assessment of the specificity and the production of baccatin III by in vivo acetylation in E. coli.
Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Catalysis; Chromatography, High Pressure Liquid; Escherichia coli; Models, Chemical; Paclitaxel; Substrate Specificity; Taxoids; Time Factors | 2006 |
Enzymatic C-4 deacetylation of 10-deacetylbaccatin III.
Topics: Acetylation; Alkaloids; Aminohydrolases; Antineoplastic Agents, Phytogenic; Bacterial Proteins; Paclitaxel; Rhodococcus; Soil Microbiology; Stenotrophomonas maltophilia; Taxoids | 2006 |
Rapid separation of four main taxoids in Taxus species by a combined LLP-SPE-HPLC (PAD) procedure.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Paclitaxel; Plants, Medicinal; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Taxoids; Taxus | 2006 |
Degradation of paclitaxel and related compounds in aqueous solutions II: Nonepimerization degradation under neutral to basic pH conditions.
Topics: Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Paclitaxel; Solutions; Stereoisomerism; Taxoids; Temperature; Water | 2008 |
Microbial transformation of cephalomannine by Luteibacter sp.
Topics: Alkaloids; Antineoplastic Agents; Bacteria; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Paclitaxel; Soil Microbiology; Taxoids; Taxus | 2007 |
Taxanes from Shells and Leaves of Corylus avellana.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Italy; Paclitaxel; Plant Leaves; Plants, Medicinal; Taxoids; Taxus | 2008 |
Taxol and 10-deacetylbaccatinIII induce distinct changes in the dynamics of caveolae.
Topics: Antineoplastic Agents; Caveolae; Caveolin 1; Green Fluorescent Proteins; HeLa Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-raf; Taxoids | 2008 |
Preparative separation and enrichment of four taxoids from Taxus chinensis needles extracts by macroporous resin column chromatography.
Topics: Chromatography, Liquid; Ethanol; Molecular Structure; Paclitaxel; Plant Extracts; Plant Leaves; Polystyrenes; Resins, Synthetic; Taxoids; Taxus | 2009 |
Production, purification and characterization of taxol and 10DAB III from a new endophytic fungus Gliocladium sp. isolated from the Indian yew tree, Taxus baccata.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gliocladium; Humans; India; Magnetic Resonance Spectroscopy; Paclitaxel; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry; Taxoids; Taxus; Weights and Measures | 2009 |
The relationship between TXS, DBAT, BAPT and DBTNBT gene expression and taxane production during the development of Taxus baccata plantlets.
Topics: Acetyltransferases; Acyltransferases; Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Gene Expression; Gene Expression Regulation, Plant; Genes, Plant; Isomerases; Paclitaxel; Plant Components, Aerial; Plant Roots; Taxoids; Taxus | 2011 |
Isolation and characterization of Stemphylium sedicola SBU-16 as a new endophytic taxol-producing fungus from Taxus baccata grown in Iran.
Topics: Ascomycota; Chromatography, High Pressure Liquid; Culture Media; DNA, Fungal; DNA, Ribosomal Spacer; Endophytes; Genes, Fungal; Iran; Isomerases; Mass Spectrometry; Mycelium; Paclitaxel; Phylogeny; Polymerase Chain Reaction; Taxoids; Taxus | 2012 |
Maintenance of membrane integrity and increase of taxanes production in hazel (Corylus avellana L.) cells induced by low-intensity ultrasound.
Topics: Alkaloids; Cell Membrane; Cells, Cultured; Corylus; Paclitaxel; Sonication; Taxoids; Time Factors | 2012 |
Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis.
Topics: Acetates; Acetyltransferases; Amino Acid Sequence; Base Sequence; Cells, Cultured; Cyclopentanes; Gene Expression; Gene Expression Regulation, Plant; Gene Library; Molecular Sequence Data; Oxylipins; Paclitaxel; Plant Leaves; Plant Proteins; Promoter Regions, Genetic; RNA Interference; Sequence Analysis, DNA; Sequence Deletion; Taxoids; Taxus; Transcription Factors; Transcriptional Activation; Two-Hybrid System Techniques | 2013 |
Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Screening Assays, Antitumor; Halogenation; Humans; Models, Molecular; Neoplasms; Paclitaxel; Structure-Activity Relationship; Taxoids; Taxus | 2013 |
Bioproduction of baccatin III, an advanced precursor of paclitaxol, with transgenic Flammulina velutipes expressing the 10-deacetylbaccatin III-10-O-acetyl transferase gene.
Topics: Acetyltransferases; Alkaloids; Flammulina; Genes, Plant; Organisms, Genetically Modified; Paclitaxel; Taxoids; Taxus | 2014 |
Simultaneous determination of seven taxoids in rat plasma by UPLC-MS/MS and pharmacokinetic study after oral administration of Taxus yunnanensis extracts.
Topics: Administration, Oral; Alkaloids; Animals; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Docetaxel; Male; Methyl Ethers; Paclitaxel; Plant Extracts; Plasma; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Taxoids; Taxus | 2015 |
[Chemical constituents of Taxus chinensis var. mairei cell cultures].
Topics: Alkenes; Cell Culture Techniques; Cells, Cultured; Diterpenes; Molecular Structure; Paclitaxel; Sitosterols; Taxoids; Taxus | 2015 |
Improving 10-deacetylbaccatin III-10-β-O-acetyltransferase catalytic fitness for Taxol production.
Topics: Acetyltransferases; Alanine; Antineoplastic Agents; Catalysis; Catalytic Domain; Glycosylation; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Mutagenesis; Mutation; Paclitaxel; Plant Extracts; Recombinant Proteins; Taxoids; Taxus; Temperature | 2017 |
Bio-production of Baccatin III, an Important Precursor of Paclitaxel by a Cost-Effective Approach.
Topics: Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Bioengineering; Biosynthetic Pathways; Computational Biology; Cost-Benefit Analysis; Genetic Engineering; Models, Molecular; Mutagenesis; Paclitaxel; Substrate Specificity; Taxoids; Taxus; Vinyl Compounds | 2018 |
Biochemical insights into the recombinant 10-deacetylbaccatin III-10-β-O-acetyltransferase enzyme from the Taxol-producing endophytic fungus Lasiodiplodia theobromae.
Topics: Acetyltransferases; Alkaloids; Ascomycota; Biocatalysis; Cloning, Molecular; Endophytes; Enzyme Stability; Fungal Proteins; Hydrogen-Ion Concentration; Kinetics; Paclitaxel; Recombinant Proteins; Taxoids; Temperature | 2019 |
High-effective biosynthesis of baccatin Ⅲ by using the alternative acetyl substrate, N-acetyl-d-glucosamine.
Topics: Acetyl Coenzyme A; Acetylglucosamine; Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Biocatalysis; Paclitaxel; Substrate Specificity; Taxoids | 2020 |
Evaluation of spore inoculum and confirmation of pathway genetic blueprint of T13αH and DBAT from a Taxol-producing endophytic fungus.
Topics: Acetyltransferases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Culture Media; Cytochrome P-450 Enzyme System; Fusarium; Paclitaxel; Spectrometry, Mass, Electrospray Ionization; Spores, Fungal; Taxoids; Temperature | 2020 |
Purification and characterization of Taxol and 10-Deacetyl baccatin III from the bark, needles, and endophytes of Taxus baccata by preparative high-performance liquid chromatography, ultra-high-performance liquid chromatography-mass spectrometry, and nucl
Topics: Chromatography, High Pressure Liquid; Endophytes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Needles; Paclitaxel; Plant Bark; Taxoids; Taxus | 2023 |