Page last updated: 2024-09-03

10-deacetylbaccatine iii and baccatin iii

10-deacetylbaccatine iii has been researched along with baccatin iii in 25 studies

Compound Research Comparison

Studies
(10-deacetylbaccatine iii)
Trials
(10-deacetylbaccatine iii)
Recent Studies (post-2010)
(10-deacetylbaccatine iii)
Studies
(baccatin iii)
Trials
(baccatin iii)
Recent Studies (post-2010) (baccatin iii)
7702699031

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (24.00)18.2507
2000's10 (40.00)29.6817
2010's7 (28.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Abe, M; Ando, M; Bai, J; Hasegawa, T; Hirose, K; Kawakami, J; Kikuchi, M; Matsubara, J; Sakai, J; Tomida, A; Tsuruo, T; Wang, J; Zhang, S1
Bu, XZ; Chen, Y; Guo, YQ; Jin, J; Qiu, J; Sun, ZH; Tang, GH; Yin, S; Zhu, CG1
Bignami, GS; Byrnes, JB; Grothaus, PG; Lazo, CB; Raybould, TJ1
Appendino, G; Bernacki, RJ; Fenoglio, I; Ojima, I; Park, YH; Pera, P; Sun, CM1
Ewald, D; Hacker, C; Hornbogen, T; Kammer, B; Weckwerth, W; Zocher, R1
Barthol, A; Croteau, R; Gatfield, D; Goleniowski, M; Hezari, M; Ketchum, RE; Walker, K1
Glowniak, K; Mroczek, T; Zobel, AM1
Abela, BA; Mulchandani, A; Sheikh, SH1
Alvinerie, P; Cresteil, T; Dubois, J; Gueritte, F; Monsarrat, B; Sonnier, M1
Chen, Y; Hu, Q; Wu, Y; Zhu, W1
Baldelli, E; Battaglia, A; Bombardelli, E; Carenzi, G; Fontana, G; Gambini, A; Gelmi, ML; Guerrini, A; Pocar, D1
Loncaric, C; Merriweather, E; Walker, KD1
Hanson, RL; Parker, WL; Patel, RN1
Fu, Y; Li, Q; Li, S; Schwarz, G; Sun, R; Zu, Y1
Loncaric, C; Walker, KD; Ward, AF1
Chen, X; Dai, J; Li, J; Zhu, P1
Furmanowa, M; Kokoszka, A; Pietrosiuk, A; Syklowska-Baranek, K1
Bonfill, M; Cusidó, RM; Goossens, A; Moyano, E; Onrubia, M; Palazón, J1
Abdolmaleki, P; Ghanati, F; Hajnoruzi, A; Mokhtari-Dizaji, M; Rezaei, A; Safari, M1
Guo, LQ; Han, F; Kang, LZ; Lin, JF; Ye, ZW; Zeng, XL1
Bai, X; Gou, X; Hou, X; Huang, M; Jin, J; Li, D; Liu, B; Zhong, G1
Guo, LQ; Huang, JJ; Lin, JF; Lin, SL; Ouyang, PL; Wei, JB; Wei, T; Wu, GP1
Jayabaskaran, C; Sah, B; Subban, K1
Guo, LQ; Han, PY; Han, WF; Huang, JJ; Lin, JF; Wei, T; Ye, AQ1
Ahmad, S; Amin, S; Mir, SR; Nurullah, M; Panda, BP; Usmani, Z1

Other Studies

25 other study(ies) available for 10-deacetylbaccatine iii and baccatin iii

ArticleYear
Structure-activity relationships of some taxoids as multidrug resistance modulator.
    Bioorganic & medicinal chemistry letters, 2007, Feb-15, Volume: 17, Issue:4

    Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Structure-Activity Relationship; Taxoids; Taxus

2007
Isolation and cytotoxicity evaluation of taxanes from the barks of Taxus wallichiana var. mairei.
    Bioorganic & medicinal chemistry letters, 2015, Mar-15, Volume: 25, Issue:6

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Mice; Molecular Conformation; NIH 3T3 Cells; Paclitaxel; Plant Bark; Structure-Activity Relationship; Taxoids; Taxus

2015
An enzyme immunoassay for the determination of taxol and taxanes in Taxus sp. tissues and human plasma.
    Journal of immunological methods, 1993, Jan-14, Volume: 158, Issue:1

    Topics: Alkaloids; Animals; Antibody Specificity; Female; Hemocyanins; Humans; Immunoenzyme Techniques; Paclitaxel; Rabbits; Taxoids; Trees; Triterpenes

1993
Structure-activity relationships of new taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.
    Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Models, Molecular; Structure-Activity Relationship; Taxoids; Triterpenes; Tumor Cells, Cultured

1994
Biosynthesis of taxol: enzymatic acetylation of 10-deacetylbaccatin-III to baccatin-III in crude extracts from roots of Taxus baccata.
    Biochemical and biophysical research communications, 1996, Dec-04, Volume: 229, Issue:1

    Topics: Acetylation; Alkaloids; Antineoplastic Agents, Phytogenic; Cell-Free System; Chromatography, High Pressure Liquid; Paclitaxel; Plant Roots; Plants, Medicinal; Taxoids; Triterpenes

1996
Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis.
    Archives of biochemistry and biophysics, 1999, Apr-15, Volume: 364, Issue:2

    Topics: Acetyltransferases; Acylation; Alkaloids; Kinetics; Paclitaxel; Plants, Medicinal; Substrate Specificity; Taxoids; Time Factors; Triterpenes

1999
Seasonal changes in the concentrations of four taxoids in Taxus baccata L. during the autumn-spring period.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 1999, Volume: 6, Issue:2

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Molecular Structure; Paclitaxel; Seasons; Taxoids; Trees; Triterpenes

1999
Development of a fluorescence immunoassay for measurement of paclitaxel in human plasma.
    Analytical biochemistry, 2000, Jul-15, Volume: 283, Issue:1

    Topics: Alkaloids; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Immunoassay; Immunoglobulin G; Paclitaxel; Reproducibility of Results; Rhodamines; Spectrometry, Fluorescence; Staphylococcal Protein A; Taxoids; Time Factors; Triterpenes

2000
Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:4

    Topics: Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; COS Cells; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Docetaxel; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Paclitaxel; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Taxoids; Triterpenes

2002
[Effects of phenylalanine, sucrose and mannitol on the growth and production of taxol, baccatin III and 10-deacetylbaccatin III in suspension cells of Taxus media].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:2

    Topics: Alkaloids; Cell Division; Cells, Cultured; Mannitol; Paclitaxel; Phenylalanine; Sucrose; Taxoids; Taxus; Triterpenes

1998
Diastereoselective 14beta-hydroxylation of baccatin III derivatives.
    The Journal of organic chemistry, 2003, Dec-12, Volume: 68, Issue:25

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Docetaxel; Hydroxylation; Molecular Structure; Oxidation-Reduction; Paclitaxel; Stereoisomerism; Taxoids

2003
Profiling a Taxol pathway 10beta-acetyltransferase: assessment of the specificity and the production of baccatin III by in vivo acetylation in E. coli.
    Chemistry & biology, 2006, Volume: 13, Issue:3

    Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Catalysis; Chromatography, High Pressure Liquid; Escherichia coli; Models, Chemical; Paclitaxel; Substrate Specificity; Taxoids; Time Factors

2006
Enzymatic C-4 deacetylation of 10-deacetylbaccatin III.
    Biotechnology and applied biochemistry, 2006, Volume: 45, Issue:Pt 2

    Topics: Acetylation; Alkaloids; Aminohydrolases; Antineoplastic Agents, Phytogenic; Bacterial Proteins; Paclitaxel; Rhodococcus; Soil Microbiology; Stenotrophomonas maltophilia; Taxoids

2006
Rapid separation of four main taxoids in Taxus species by a combined LLP-SPE-HPLC (PAD) procedure.
    Journal of separation science, 2006, Volume: 29, Issue:9

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Paclitaxel; Plants, Medicinal; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Taxoids; Taxus

2006
Expression of an acetyl-CoA synthase and a CoA-transferase in Escherichia coli to produce modified taxanes in vivo.
    Biotechnology journal, 2007, Volume: 2, Issue:2

    Topics: Alkaloids; Butyrates; Coenzyme A Ligases; Coenzyme A-Transferases; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Enzymologic; Molecular Structure; Substrate Specificity; Taxoids

2007
Microbial transformation of cephalomannine by Luteibacter sp.
    Journal of natural products, 2007, Volume: 70, Issue:12

    Topics: Alkaloids; Antineoplastic Agents; Bacteria; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Paclitaxel; Soil Microbiology; Taxoids; Taxus

2007
Enhancement of taxane production in hairy root culture of Taxus x media var. Hicksii.
    Journal of plant physiology, 2009, Nov-15, Volume: 166, Issue:17

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Benzoates; Biomass; Culture Media; Cyclopentanes; Oxylipins; Phenylalanine; Plant Growth Regulators; Plant Roots; Plants, Genetically Modified; Taxoids; Taxus; Tissue Culture Techniques

2009
The relationship between TXS, DBAT, BAPT and DBTNBT gene expression and taxane production during the development of Taxus baccata plantlets.
    Plant science : an international journal of experimental plant biology, 2011, Volume: 181, Issue:3

    Topics: Acetyltransferases; Acyltransferases; Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Gene Expression; Gene Expression Regulation, Plant; Genes, Plant; Isomerases; Paclitaxel; Plant Components, Aerial; Plant Roots; Taxoids; Taxus

2011
Maintenance of membrane integrity and increase of taxanes production in hazel (Corylus avellana L.) cells induced by low-intensity ultrasound.
    Biotechnology letters, 2012, Volume: 34, Issue:6

    Topics: Alkaloids; Cell Membrane; Cells, Cultured; Corylus; Paclitaxel; Sonication; Taxoids; Time Factors

2012
Bioproduction of baccatin III, an advanced precursor of paclitaxol, with transgenic Flammulina velutipes expressing the 10-deacetylbaccatin III-10-O-acetyl transferase gene.
    Journal of the science of food and agriculture, 2014, Volume: 94, Issue:12

    Topics: Acetyltransferases; Alkaloids; Flammulina; Genes, Plant; Organisms, Genetically Modified; Paclitaxel; Taxoids; Taxus

2014
Simultaneous determination of seven taxoids in rat plasma by UPLC-MS/MS and pharmacokinetic study after oral administration of Taxus yunnanensis extracts.
    Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107

    Topics: Administration, Oral; Alkaloids; Animals; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Docetaxel; Male; Methyl Ethers; Paclitaxel; Plant Extracts; Plasma; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Taxoids; Taxus

2015
Bio-production of Baccatin III, an Important Precursor of Paclitaxel by a Cost-Effective Approach.
    Molecular biotechnology, 2018, Volume: 60, Issue:7

    Topics: Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Bioengineering; Biosynthetic Pathways; Computational Biology; Cost-Benefit Analysis; Genetic Engineering; Models, Molecular; Mutagenesis; Paclitaxel; Substrate Specificity; Taxoids; Taxus; Vinyl Compounds

2018
Biochemical insights into the recombinant 10-deacetylbaccatin III-10-β-O-acetyltransferase enzyme from the Taxol-producing endophytic fungus Lasiodiplodia theobromae.
    FEMS microbiology letters, 2019, 04-01, Volume: 366, Issue:7

    Topics: Acetyltransferases; Alkaloids; Ascomycota; Biocatalysis; Cloning, Molecular; Endophytes; Enzyme Stability; Fungal Proteins; Hydrogen-Ion Concentration; Kinetics; Paclitaxel; Recombinant Proteins; Taxoids; Temperature

2019
High-effective biosynthesis of baccatin Ⅲ by using the alternative acetyl substrate, N-acetyl-d-glucosamine.
    Journal of applied microbiology, 2020, Volume: 129, Issue:2

    Topics: Acetyl Coenzyme A; Acetylglucosamine; Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Biocatalysis; Paclitaxel; Substrate Specificity; Taxoids

2020
Purification and characterization of Taxol and 10-Deacetyl baccatin III from the bark, needles, and endophytes of Taxus baccata by preparative high-performance liquid chromatography, ultra-high-performance liquid chromatography-mass spectrometry, and nucl
    Journal of separation science, 2023, Volume: 46, Issue:6

    Topics: Chromatography, High Pressure Liquid; Endophytes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Needles; Paclitaxel; Plant Bark; Taxoids; Taxus

2023