Page last updated: 2024-09-04

10,11-methylenedioxy-n-propylnoraporphine and n-n-propylnorapomorphine

10,11-methylenedioxy-n-propylnoraporphine has been researched along with n-n-propylnorapomorphine in 6 studies

Compound Research Comparison

Studies
(10,11-methylenedioxy-n-propylnoraporphine)
Trials
(10,11-methylenedioxy-n-propylnoraporphine)
Recent Studies (post-2010)
(10,11-methylenedioxy-n-propylnoraporphine)
Studies
(n-n-propylnorapomorphine)
Trials
(n-n-propylnorapomorphine)
Recent Studies (post-2010) (n-n-propylnorapomorphine)
901274412
90131010

Protein Interaction Comparison

ProteinTaxonomy10,11-methylenedioxy-n-propylnoraporphine (IC50)n-n-propylnorapomorphine (IC50)
Tyrosine 3-monooxygenaseHomo sapiens (human)0.3
DRattus norvegicus (Norway rat)0.3195
D(3) dopamine receptorRattus norvegicus (Norway rat)0.2394
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.2394
D(4) dopamine receptorRattus norvegicus (Norway rat)0.2394
D(2) dopamine receptorRattus norvegicus (Norway rat)0.1925

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Baldessarini, RJ; Lampen, P; Neumeyer, JL1
Arana, GW; Baldessarini, RJ; Campbell, A; Kula, NS; Neumeyer, JL; Ram, VJ; Sperk, G1
Kuttab, SH; Maksoud, HM; Neumeyer, JL; Vouros, P1
Baldessarini, RJ; Campbell, A; Neumeyer, JL; Ram, VJ1
Baldessarini, RJ; Campbell, A; Neumeyer, JL; Sperk, G; Stoll, A1
Liu, C; Park, H; Urs, AN; Urs, NM; Wang, Q; Zimmerman, J1

Other Studies

6 other study(ies) available for 10,11-methylenedioxy-n-propylnoraporphine and n-n-propylnorapomorphine

ArticleYear
High-performance liquid chromatographic separation and electrochemical or spectrophotometric determination of R(-)N-n-propylnorapomorphine and R(-)10,11-methylenedioxy-N-n-propylnoraporphine in primate plasma.
    Journal of chromatography, 1988, Apr-29, Volume: 426, Issue:2

    Topics: Animals; Apomorphine; Aporphines; Chromatography, High Pressure Liquid; Electrochemistry; Macaca fascicularis; Spectrophotometry, Ultraviolet

1988
An orally effective, long-acting dopaminergic prodrug: (-)-10,11-methylenedioxy-N-propylnoraporphine.
    European journal of pharmacology, 1982, Jan-08, Volume: 77, Issue:1

    Topics: Administration, Oral; Animals; Apomorphine; Brain; Cattle; Cyclic AMP; Humans; Rats; Receptors, Dopamine; Stereotyped Behavior

1982
Analysis of N-n-propylnorapomorphine in plasma and tissue by capillary gas chromatography--electron-capture detection.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Animals; Apomorphine; Brain; Brain Chemistry; Chromatography, Gas; Rats; Receptors, Dopamine; Trifluoroacetic Acid

1983
Behavioral effects of (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines.
    Neuropharmacology, 1982, Volume: 21, Issue:10

    Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Dose-Response Relationship, Drug; Humans; Male; Proadifen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Structure-Activity Relationship

1982
Tissue levels of N-n-propylnorapomorphine after treatment with (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally long-acting prodrug active at central dopamine receptors.
    Neuropharmacology, 1982, Volume: 21, Issue:12

    Topics: Animals; Apomorphine; Aporphines; Chromatography, High Pressure Liquid; Humans; Rats; Receptors, Dopamine; Stereotyped Behavior

1982
Structure-Functional-Selectivity Relationship Studies of Novel Apomorphine Analogs to Develop D1R/D2R Biased Ligands.
    ACS medicinal chemistry letters, 2020, Mar-12, Volume: 11, Issue:3

    Topics:

2020