1-propyl-2-methyl-3-hydroxypyrid-4-one has been researched along with deferoxamine in 3 studies
| Studies (1-propyl-2-methyl-3-hydroxypyrid-4-one) | Trials (1-propyl-2-methyl-3-hydroxypyrid-4-one) | Recent Studies (post-2010) (1-propyl-2-methyl-3-hydroxypyrid-4-one) | Studies (deferoxamine) | Trials (deferoxamine) | Recent Studies (post-2010) (deferoxamine) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 6,703 | 240 | 1,266 |
| Protein | Taxonomy | 1-propyl-2-methyl-3-hydroxypyrid-4-one (IC50) | deferoxamine (IC50) |
|---|---|---|---|
| Lysine-specific demethylase 4A | Homo sapiens (human) | 3.275 | |
| Deoxyhypusine hydroxylase | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dobbin, PS; Hall, AD; Hider, RC; Porter, JB; Sarpong, P; Taylor, PD; van der Helm, D; Xiao, G | 1 |
| Dandona, P; Hoffbrand, AV; Jeremy, JY; Kontoghiorghes, GJ | 1 |
| Kontoghiorghes, GJ | 1 |
3 other study(ies) available for 1-propyl-2-methyl-3-hydroxypyrid-4-one and deferoxamine
| Article | Year |
|---|---|
Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential.
Topics: Administration, Oral; Animals; Crystallography; Deferoxamine; Horses; Humans; Iron; Iron Chelating Agents; Liver; Mice; Pyridones; Rats; Stereoisomerism; Structure-Activity Relationship | 1993 |
The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.
Topics: Aluminum; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Calcimycin; Deferiprone; Deferoxamine; Epinephrine; Epoprostenol; Hydrogen Peroxide; Iron; Iron Chelating Agents; Male; Pyridones; Rats; Rats, Inbred Strains | 1988 |
Dose response studies using desferrioxamine and orally active chelators in a mouse model.
Topics: Administration, Oral; Animals; Deferiprone; Deferoxamine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Iron; Iron Chelating Agents; Male; Mice; Pyridones; Time Factors | 1986 |