1-propyl-2-methyl-3-hydroxypyrid-4-one has been researched along with deferiprone in 6 studies
| Studies (1-propyl-2-methyl-3-hydroxypyrid-4-one) | Trials (1-propyl-2-methyl-3-hydroxypyrid-4-one) | Recent Studies (post-2010) (1-propyl-2-methyl-3-hydroxypyrid-4-one) | Studies (deferiprone) | Trials (deferiprone) | Recent Studies (post-2010) (deferiprone) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 1,016 | 142 | 409 |
| Protein | Taxonomy | 1-propyl-2-methyl-3-hydroxypyrid-4-one (IC50) | deferiprone (IC50) |
|---|---|---|---|
| Lysine-specific demethylase 6A | Homo sapiens (human) | 4.2 | |
| Lysine-specific demethylase 4A | Homo sapiens (human) | 3.275 | |
| Lysine-specific demethylase 5C | Homo sapiens (human) | 5.6 | |
| Lysine-specific demethylase 2B | Homo sapiens (human) | 8.1 | |
| Deoxyhypusine hydroxylase | Homo sapiens (human) | 5 | |
| Lysine-specific demethylase 2A | Homo sapiens (human) | 6.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dobbin, PS; Hall, AD; Hider, RC; Porter, JB; Sarpong, P; Taylor, PD; van der Helm, D; Xiao, G | 1 |
| Dekhordi, LS; Hider, RC; Jin, Y; Khodr, H; Liu, Z; Rai, BL | 1 |
| Caisová, D; Eybl, V; Kontoghiorghes, GJ; Koutenský, J | 1 |
| Dandona, P; Hoffbrand, AV; Jeremy, JY; Kontoghiorghes, GJ | 1 |
| Kontoghiorghes, GJ | 1 |
| Ghosh, S; Gleason, WB; Grant, DJ; Ojala, WH | 1 |
6 other study(ies) available for 1-propyl-2-methyl-3-hydroxypyrid-4-one and deferiprone
| Article | Year |
|---|---|
Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential.
Topics: Administration, Oral; Animals; Crystallography; Deferoxamine; Horses; Humans; Iron; Iron Chelating Agents; Liver; Mice; Pyridones; Rats; Stereoisomerism; Structure-Activity Relationship | 1993 |
Synthesis, physicochemical properties, and evaluation of N-substituted-2-alkyl-3-hydroxy-4(1H)-pyridinones.
Topics: Animals; Bile; Ferritins; Iron; Iron Chelating Agents; Male; Molecular Conformation; Pyridones; Rats; Rats, Inbred F344; Solutions; Structure-Activity Relationship | 1998 |
Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice.
Topics: Animals; Cadmium; Carbon Tetrachloride; Deferiprone; Glutathione; In Vitro Techniques; Indium; Iron; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Pyridones | 1991 |
The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.
Topics: Aluminum; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Calcimycin; Deferiprone; Deferoxamine; Epinephrine; Epoprostenol; Hydrogen Peroxide; Iron; Iron Chelating Agents; Male; Pyridones; Rats; Rats, Inbred Strains | 1988 |
Dose response studies using desferrioxamine and orally active chelators in a mouse model.
Topics: Administration, Oral; Animals; Deferiprone; Deferoxamine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Iron; Iron Chelating Agents; Male; Mice; Pyridones; Time Factors | 1986 |
Relationships between crystal structures, thermal properties, and solvate stability of dialkylhydroxypyridones and their formic acid solvates.
Topics: Calorimetry, Differential Scanning; Crystallography, X-Ray; Deferiprone; Formates; Hydrogen Bonding; Iron Chelating Agents; Pyridones; Thermodynamics | 1995 |