Page last updated: 2024-09-03

1-propyl-2-methyl-3-hydroxypyrid-4-one and 1-ethyl-2-methyl-3-hydroxypyridin-4-one

1-propyl-2-methyl-3-hydroxypyrid-4-one has been researched along with 1-ethyl-2-methyl-3-hydroxypyridin-4-one in 5 studies

Compound Research Comparison

Studies
(1-propyl-2-methyl-3-hydroxypyrid-4-one)
Trials
(1-propyl-2-methyl-3-hydroxypyrid-4-one)
Recent Studies (post-2010)
(1-propyl-2-methyl-3-hydroxypyrid-4-one)
Studies
(1-ethyl-2-methyl-3-hydroxypyridin-4-one)
Trials
(1-ethyl-2-methyl-3-hydroxypyridin-4-one)
Recent Studies (post-2010) (1-ethyl-2-methyl-3-hydroxypyridin-4-one)
8001301

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dobbin, PS; Hall, AD; Hider, RC; Porter, JB; Sarpong, P; Taylor, PD; van der Helm, D; Xiao, G1
Dekhordi, LS; Hider, RC; Jin, Y; Khodr, H; Liu, Z; Rai, BL1
Caisová, D; Eybl, V; Kontoghiorghes, GJ; Koutenský, J1
Dandona, P; Hoffbrand, AV; Jeremy, JY; Kontoghiorghes, GJ1
Kontoghiorghes, GJ1

Other Studies

5 other study(ies) available for 1-propyl-2-methyl-3-hydroxypyrid-4-one and 1-ethyl-2-methyl-3-hydroxypyridin-4-one

ArticleYear
Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential.
    Journal of medicinal chemistry, 1993, Aug-20, Volume: 36, Issue:17

    Topics: Administration, Oral; Animals; Crystallography; Deferoxamine; Horses; Humans; Iron; Iron Chelating Agents; Liver; Mice; Pyridones; Rats; Stereoisomerism; Structure-Activity Relationship

1993
Synthesis, physicochemical properties, and evaluation of N-substituted-2-alkyl-3-hydroxy-4(1H)-pyridinones.
    Journal of medicinal chemistry, 1998, Aug-27, Volume: 41, Issue:18

    Topics: Animals; Bile; Ferritins; Iron; Iron Chelating Agents; Male; Molecular Conformation; Pyridones; Rats; Rats, Inbred F344; Solutions; Structure-Activity Relationship

1998
Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1991, Volume: 14

    Topics: Animals; Cadmium; Carbon Tetrachloride; Deferiprone; Glutathione; In Vitro Techniques; Indium; Iron; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Pyridones

1991
The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.
    The Biochemical journal, 1988, Aug-15, Volume: 254, Issue:1

    Topics: Aluminum; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Calcimycin; Deferiprone; Deferoxamine; Epinephrine; Epoprostenol; Hydrogen Peroxide; Iron; Iron Chelating Agents; Male; Pyridones; Rats; Rats, Inbred Strains

1988
Dose response studies using desferrioxamine and orally active chelators in a mouse model.
    Scandinavian journal of haematology, 1986, Volume: 37, Issue:1

    Topics: Administration, Oral; Animals; Deferiprone; Deferoxamine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Iron; Iron Chelating Agents; Male; Mice; Pyridones; Time Factors

1986